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Related papers: MUSE: Multi-Scale Dense Self-Distillation for Nucl…

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In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Aman Shrivastava , P. Thomas Fletcher

Deep Learning has emerged as a promising approach for skin lesion analysis. However, existing methods mostly rely on fully supervised learning, requiring extensive labeled data, which is challenging and costly to obtain. To alleviate this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Siyamalan Manivannan

Machine learning (ML) research has yielded powerful tools for training accurate prediction models despite complex multivariate associations (e.g. interactions and heterogeneity). In fields such as medicine, improved interpretability of ML…

Machine Learning · Computer Science 2021-04-28 Robert Zhang , Rachael Stolzenberg-Solomon , Shannon M. Lynch , Ryan J. Urbanowicz

The introduction of lung cancer screening programs will produce an unprecedented amount of chest CT scans in the near future, which radiologists will have to read in order to decide on a patient follow-up strategy. According to the current…

Novel Class Discovery (NCD) aims to discover unknown and novel classes in an unlabeled set by leveraging knowledge already learned about known classes. Existing works focus on instance-level or class-level knowledge representation and build…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Yuzheng Wang , Zhaoyu Chen , Dingkang Yang , Yunquan Sun , Lizhe Qi

The problem of recognizing various types of tissues present in multi-gigapixel histology images is an important fundamental pre-requisite for downstream analysis of the tumor microenvironment in a bottom-up analysis paradigm for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-02 Nima Hatami , Mohsin Bilal , Nasir Rajpoot

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

General Multimodal Large Language Models (MLLMs) often underperform in capturing domain-specific nuances in medical diagnosis, trailing behind fully supervised baselines. Although fine-tuning provides a remedy, the high costs of expert…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Wenkai Zhao , Zipei Wang , Mengjie Fang , Di Dong , Jie Tian , Lingwei Zhang

Recent advances in deep learning have greatly facilitated the automated segmentation of ultrasound images, which is essential for nodule morphological analysis. Nevertheless, most existing methods depend on extensive and precise annotations…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Xingyue Zhao , Zhongyu Li , Xiangde Luo , Peiqi Li , Peng Huang , Jianwei Zhu , Yang Liu , Jihua Zhu , Meng Yang , Shi Chang , Jun Dong

The level of PD-L1 expression in immunohistochemistry (IHC) assays is a key biomarker for the identification of Non-Small-Cell-Lung-Cancer (NSCLC) patients that may respond to anti PD-1/PD-L1 treatments. The quantification of PD-L1…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Ansh Kapil , Armin Meier , Aleksandra Zuraw , Keith Steele , Marlon Rebelatto , Günter Schmidt , Nicolas Brieu

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham

Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Yupei Zhang , Xiaofei Wang , Anran Liu , Lequan Yu , Chao Li

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Semi-supervised segmentation methods have demonstrated promising results in natural scenarios, providing a solution to reduce dependency on manual annotation. However, these methods face significant challenges when directly applied to…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Ye Zhang , Ziyue Wang , Yifeng Wang , Hao Bian , Linghan Cai , Hengrui Li , Lingbo Zhang , Yongbing Zhang

In recent years, self-supervised learning has emerged as a promising approach in addressing the issues of label dependency and poor generalization performance in traditional GNNs. However, existing self-supervised methods have limited…

Machine Learning · Computer Science 2023-08-01 Mengyi Yuan , Minjie Chen , Xiang Li

Advances in self-supervised learning are essential for enhancing feature extraction and understanding in point cloud processing. This paper introduces PMT-MAE (Point MLP-Transformer Masked Autoencoder), a novel self-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Qiang Zheng , Chao Zhang , Jian Sun

Segmentation of pathological images is a crucial step for accurate cancer diagnosis. However, acquiring dense annotations of such images for training is labor-intensive and time-consuming. To address this issue, Semi-Supervised Learning…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Lanfeng Zhong , Xin Liao , Shaoting Zhang , Guotai Wang

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Yinsheng He , Xingyu Li

In this paper, we introduce an unsupervised cancer segmentation framework for histology images. The framework involves an effective contrastive learning scheme for extracting distinctive visual representations for segmentation. The encoder…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Yilong Li , Yaqi Wang , Huiyu Zhou , Huaqiong Wang , Gangyong Jia , Qianni Zhang

Background: Image classification can be considered one of the key pillars of medical image analysis. Deep learning (DL) faces challenges that prevent its practical applications despite the remarkable improvement in medical image…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Shahabedin Nabavi , Kian Anvari Hamedani , Mohsen Ebrahimi Moghaddam , Ahmad Ali Abin , Alejandro F. Frangi