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An important objective in computational biology is the efficient integration of multi-omics data. The task of integration comes with challenges: multi-omics data are most often unpaired (requiring diagonal integration), partially labeled…

Machine Learning · Computer Science 2025-09-16 Daniel Lepe-Soltero , Thierry Artières , Anaïs Baudot , Paul Villoutreix

Objective: Multimodal measurements of the same phenomena provide complementary information and highlight different perspectives, albeit each with their own limitations. A focus on a single modality may lead to incorrect inferences, which is…

Learning similarity is a key aspect in medical image analysis, particularly in recommendation systems or in uncovering the interpretation of anatomical data in images. Most existing methods learn such similarities in the embedding space…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Sukesh Adiga , Jose Dolz , Herve Lombaert

According to the World Health Organization, the number of mental disorder patients, especially depression patients, has grown rapidly and become a leading contributor to the global burden of disease. However, the present common practice of…

In network meta-analysis (NMA), we synthesize all relevant evidence about health outcomes with competing treatments. The evidence may come from randomized controlled trials (RCT) or non-randomized studies (NRS) as individual participant…

Missing data is a significant problem impacting all domains. State-of-the-art framework for minimizing missing data bias is multiple imputation, for which the choice of an imputation model remains nontrivial. We propose a multiple…

Machine Learning · Computer Science 2018-02-20 Lovedeep Gondara , Ke Wang

Learning medical visual representations directly from paired images and reports through multimodal self-supervised learning has emerged as a novel and efficient approach to digital diagnosis in recent years. However, existing models suffer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Libin Lan , Hongxing Li , Zunhui Xia , Juan Zhou , Xiaofei Zhu , Yongmei Li , Yudong Zhang , Xin Luo

For the early identification, diagnosis, and treatment of mental health illnesses, the integration of deep learning (DL) and machine learning (ML) has started playing a significant role. By evaluating complex data from imaging, genetics,…

We propose a novel framework for integrating fragmented multi-modal data in Alzheimer's disease (AD) research using large language models (LLMs) and knowledge graphs. While traditional multimodal analysis requires matched patient IDs across…

Machine Learning · Computer Science 2025-08-19 Kanan Kiguchi , Yunhao Tu , Katsuhiro Ajito , Fady Alnajjar , Kazuyuki Murase

Autism Spectrum Disorder (ASD) is a severe neuropsychiatric disorder that affects intellectual development, social behavior, and facial features, and the number of cases is still significantly increasing. Due to the variety of symptoms ASD…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Ryan Liu , Spencer He

The widespread adoption of social media has heightened interest in its psychological effects, particularly on mental health indicators such as anxiety, depression, loneliness, and sleep quality, as these platforms increasingly influence…

Machine Learning · Computer Science 2026-04-28 Md All Shahria , Sanjeda Dewan Mithila , Touhid Alam , Mohammad Sakib Mahmood , Mahfuza Khatun

Real-world clinical problems are often characterized by multimodal data, usually associated with incomplete views and limited sample sizes in their cohorts, posing significant limitations for machine learning algorithms. In this work, we…

The expression of mental health symptoms through non-traditional means, such as memes, has gained remarkable attention over the past few years, with users often highlighting their mental health struggles through figurative intricacies…

Accurate diagnosis of autism spectrum disorder (ASD) based on neuroimaging data has significant implications, as extracting useful information from neuroimaging data for ASD detection is challenging. Even though machine learning techniques…

Machine Learning · Computer Science 2022-06-13 Ruimin Ma , Yanlin Wang , Yanjie Wei , Yi Pan

Multi-level modeling is an important approach for analyzing complex survey data using multi-stage sampling. However, estimation of multi-level models can be challenging when we combine several datasets with distinct hierarchies with…

Methodology · Statistics 2023-09-26 Seho Park , A James OMalley

Large-scale multimodal pre-trained models like CLIP rely heavily on high-quality training data, yet raw web-crawled datasets are often noisy, misaligned, and redundant, leading to inefficient training and suboptimal generalization. Existing…

Machine Learning · Computer Science 2026-02-06 Guanjie Cheng , Boyi Li , Lingyu Sun , Mengying Zhu , Yangyang Wu , Xinkui Zhao , Shuiguang Deng

We developed a novel, interpretable multimodal classification method to identify symptoms of mood disorders viz. depression, anxiety and anhedonia using audio, video and text collected from a smartphone application. We used CNN-based…

Machine Learning · Computer Science 2021-09-08 Tathagata Banerjee , Matthew Kollada , Pablo Gersberg , Oscar Rodriguez , Jane Tiller , Andrew E Jaffe , John Reynders

Modern data collection in many data paradigms, including bioinformatics, often incorporates multiple traits derived from different data types (i.e. platforms). We call this data multi-block, multi-view, or multi-omics data. The emergent…

Methodology · Statistics 2024-01-18 Jack B. Prothero , Meilei Jiang , Jan Hannig , Quoc Tran-Dinh , Andrew Ackerman , J. S. Marron

The current methods for diagnosing Alzheimer Disease using Magnetic Resonance Imaging (MRI) have significant limitations. Many previous studies used 2D Transformers to analyze individual brain slices independently, potentially losing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Juan A. Castro-Silva , Maria N. Moreno Garcia , Diego H. Peluffo-Ordoñez

Automated identification of DICOM image series is essential for large-scale medical image analysis, quality control, protocol harmonization, and reliable downstream processing. However, DICOM series classification remains challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Tuan Truong , Melanie Dohmen , Sara Lorio , Matthias Lenga