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The primary method for identifying mental disorders automatically has traditionally involved using binary classifiers. These classifiers are trained using behavioral data obtained from an interview setup. In this training process, data from…

Neurons and Cognition · Quantitative Biology 2023-08-11 Rohan Kumar Gupta , Rohit Sinha

Finding the underlying relationships among multiple imaging modalities in a coherent fashion is one of challenging problems in the multimodal analysis. In this study, we propose a novel multimodal network approach based on multidi-…

Quantitative Methods · Quantitative Biology 2016-02-26 Hyekyoung Lee , Hyejin Kang , Moo K. Chung , Seonhee Lim , Bung-Nyun Kim , Dong Soo Lee

In recent years, there has been a surge of interest in research on automatic mental health detection (MHD) from social media data leveraging advances in natural language processing and machine learning techniques. While significant progress…

Computation and Language · Computer Science 2022-12-21 Sourabh Zanwar , Daniel Wiechmann , Yu Qiao , Elma Kerz

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

The imaging community has increasingly adopted machine learning (ML) methods to provide individualized imaging signatures related to disease diagnosis, prognosis, and response to treatment. Clinical neuroscience and cancer imaging have been…

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

Quantitative Methods · Quantitative Biology 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

In the last two decades, unsupervised latent variable models---blind source separation (BSS) especially---have enjoyed a strong reputation for the interpretable features they produce. Seldom do these models combine the rich diversity of…

Machine Learning · Statistics 2019-11-12 Rogers F. Silva , Sergey M. Plis , Tulay Adali , Marios S. Pattichis , Vince D. Calhoun

This review provides a dynamical systems perspective on psychiatric symptoms and disease, and discusses its potential implications for diagnosis, prognosis, and treatment. After a brief introduction into the theory of dynamical systems, we…

Neurons and Cognition · Quantitative Biology 2018-09-18 Daniel Durstewitz , Quentin J. M. Huys , Georgia Koppe

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of…

Applications · Statistics 2025-07-22 Eleonora Vitanza , Pietro DeLellis , Chiara Mocenni , Manuel Ruiz Marin

This study evaluates the performance of various supervised machine learning models in analyzing highly correlated neural signaling data from the Adolescent Brain Cognitive Development (ABCD) Study, with a focus on predicting…

Neurons and Cognition · Quantitative Biology 2024-07-02 Xinyu Shen , Qimin Zhang , Huili Zheng , Weiwei Qi

Autism spectrum disorder (ASD) is a developmental disorder characterized by significant social communication impairments and difficulties perceiving and presenting communication cues. Machine learning techniques have been broadly adopted to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jicheng Li , Vuthea Chheang , Pinar Kullu , Eli Brignac , Zhang Guo , Kenneth E. Barner , Anjana Bhat , Roghayeh Leila Barmaki

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD) and thus enrolling MCI subjects to undergo clinical trials is worthwhile. However, MCI groups usually show significant diversity and heterogeneity in the…

Quantitative Methods · Quantitative Biology 2025-08-26 Muheng Shang , Jin Zhang , Junwei Han , Lei Du

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from conventional approaches may not be…

Applications · Statistics 2023-09-28 Lingsong Meng , Zhiguang Huo

Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

Artificial Intelligence · Computer Science 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Attention-deficit/hyperactivity disorder (ADHD) is a prevalent mental health condition affecting both children and adults, yet it remains severely underdiagnosed. Recent advances in artificial intelligence, particularly in Natural Language…

Computation and Language · Computer Science 2024-11-26 D. Wiechmann , E. Kempa , E. Kerz , Y. Qiao

Prompt and accurate detection of system anomalies is essential to ensure the reliability of software systems. Unlike manual efforts that exploit all available run-time information, existing approaches usually leverage only a single type of…

Software Engineering · Computer Science 2023-02-16 Baitong Li , Tianyi Yang , Zhuangbin Chen , Yuxin Su , Yongqiang Yang , Michael R. Lyu

Detecting collaborative and problem-solving behaviours from digital traces to interpret students' collaborative problem solving (CPS) competency is a long-term goal in the Artificial Intelligence in Education (AIEd) field. Although…

Computation and Language · Computer Science 2025-04-22 K. Wong , B. Wu , S. Bulathwela , M. Cukurova

The LIPGENE-SU.VI.MAX study, like many others, recorded high dimensional continuous phenotypic data and categorical genotypic data. LIPGENE-SU.VI.MAX focuses on the need to account for both phenotypic and genetic factors when studying the…