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Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by atypical functional brain connectivity and subtle structural alterations. rs-fMRI has been widely used to identify disruptions in large-scale brain…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ansar Rahman , Hassan Shojaee-Mend , Sepideh Hatamikia

Depression is a widespread mental health issue affecting diverse age groups, with notable prevalence among college students and the elderly. However, existing datasets and detection methods primarily focus on young adults, neglecting the…

Multimodal intent understanding is a significant research area that requires effective leveraging of multiple modalities to analyze human language. Existing methods face two main challenges in this domain. Firstly, they have limitations in…

Multimedia · Computer Science 2025-05-26 Hanlei Zhang , Qianrui Zhou , Hua Xu , Jianhua Su , Roberto Evans , Kai Gao

Recently, the application of deep learning models to diagnose neuropsychiatric diseases from brain imaging data has received more and more attention. However, in practice, exploring interactions in brain functional connectivity based on…

Machine Learning · Computer Science 2022-06-29 Sartaj Ahmed Salman , Zhichao Lian , Milad Taleby Ahvanooey , Hiroki Takahashi , Yuduo Zhang

Converging evidence indicates that the heterogeneity of cognitive profiles may arise through detectable alternations in brain functions. Particularly, brain functional connectivity, measured under resting and cognitive states, characterizes…

Applications · Statistics 2023-02-22 Tianqi Chen , Chichun Tan , Hongyu Zhao , Todd Constable , Sarah Yip , Yize Zhao

Recent advances in remote health monitoring systems have significantly benefited patients and played a crucial role in improving their quality of life. However, while physiological health-focused solutions have demonstrated increasing…

Machine Learning · Computer Science 2023-03-28 Shayan Fazeli , Lionel Levine , Mehrab Beikzadeh , Baharan Mirzasoleiman , Bita Zadeh , Tara Peris , Majid Sarrafzadeh

Amid growing global mental health concerns, particularly among vulnerable groups, natural language processing offers a tremendous potential for early detection and intervention of people's mental disorders via analyzing their postings and…

Machine Learning · Computer Science 2023-11-10 Haijian Shao , Ming Zhu , Shengjie Zhai

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Psychiatric disorders have historically been classified using symptom information alone. With the advent of new technologies that allowed researchers to investigate brain mechanisms more directly, interest in the mechanistic rationale…

Neurons and Cognition · Quantitative Biology 2020-07-02 Lucas Miranda , Riya Paul , Benno Pütz , Bertram Müller-Myhsok

Time series anomaly detection plays a critical role in many dynamic systems. Despite its importance, previous approaches have primarily relied on unimodal numerical data, overlooking the importance of complementary information from other…

Machine Learning · Computer Science 2026-03-24 Shiyan Hu , Jianxin Jin , Yang Shu , Peng Chen , Bin Yang , Chenjuan Guo

Mental disease detection (MDD) from social media has suffered from poor generalizability and interpretability, due to lack of symptom modeling. This paper introduces PsySym, the first annotated symptom identification corpus of multiple…

Computation and Language · Computer Science 2022-05-24 Zhiling Zhang , Siyuan Chen , Mengyue Wu , Kenny Q. Zhu

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Multi-modality imaging improves disease diagnosis and reveals distinct deviations in tissues with anatomical properties. The existence of completely aligned and paired multi-modality neuroimaging data has proved its effectiveness in brain…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Guoyang Xie , Yawen Huang , Jinbao Wang , Jiayi Lyu , Feng Zheng , Yefeng Zheng , Yaochu Jin

mmid (Multi-Modal Integration and Downstream analyses for healthcare analytics) is a Python package that offers multi-modal fusion and imputation, classification, time-to-event prediction and clustering functionalities under a single…

Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics and information integration during…

Neurons and Cognition · Quantitative Biology 2025-06-24 Shervin Safavi , Danaé Rolland , Philipp Sterzer , Renaud Jardri , Pantelis Leptourgos

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

Machine Learning · Computer Science 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

Early screening for anxiety and appropriate interventions are essential to reduce the incidence of self-harm and suicide in patients. Due to limited medical resources, traditional methods that overly rely on physician expertise and…

Machine Learning · Computer Science 2023-03-17 Haimiao Mo , Shuai Ding , Siu Cheung Hui

Multimodal models often over-rely on dominant modalities, failing to achieve optimal performance. While prior work focuses on modifying training objectives or optimization procedures, data-centric solutions remain underexplored. We propose…

Machine Learning · Computer Science 2025-10-01 Seong-Hyeon Hwang , Soyoung Choi , Steven Euijong Whang

Differential diagnosis of mental disorders remains a fundamental challenge in real-world clinical practice, where multiple conditions often exhibit overlapping symptoms. However, most existing public datasets are developed under…