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Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Medical question answering (QA) is a reasoning-intensive task that remains challenging for large language models (LLMs) due to hallucinations and outdated domain knowledge. Retrieval-Augmented Generation (RAG) provides a promising…

Computation and Language · Computer Science 2025-05-01 Xuanzhao Dong , Wenhui Zhu , Hao Wang , Xiwen Chen , Peijie Qiu , Rui Yin , Yi Su , Yalin Wang

To efficiently combat the spread of LLM-generated misinformation, we present RADAR, a Retrieval-Augmented Detector with Adversarial Refinement for robust fake news detection. Our approach employs a generator that rewrites real articles with…

Computation and Language · Computer Science 2026-03-19 Song-Duo Ma , Yi-Hung Liu , Hsin-Yu Lin , Pin-Yu Chen , Hong-Yan Huang , Shau-Yung Hsu , Yun-Nung Chen

The growing integration of vision-language models (VLMs) in medical applications offers promising support for diagnostic reasoning. However, current medical VLMs often face limitations in generalization, transparency, and computational…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Tan-Hanh Pham , Chris Ngo

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Data visualizations like charts are fundamental tools for quantitative analysis and decision-making across fields, requiring accurate interpretation and mathematical reasoning. The emergence of Multimodal Large Language Models (MLLMs)…

Artificial Intelligence · Computer Science 2025-08-26 Anku Rani , Aparna Garimella , Apoorv Saxena , Balaji Vasan Srinivasan , Paul Pu Liang

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Deep Research agents are rapidly emerging as primary consumers of modern retrieval systems. Unlike human users who issue and refine queries without documenting their intermediate thought processes, Deep Research agents generate explicit…

Computation and Language · Computer Science 2026-03-10 Zijian Chen , Xueguang Ma , Shengyao Zhuang , Jimmy Lin , Akari Asai , Victor Zhong

Clinical decision support requires not only correct answers but also clinically valid reasoning. We propose Differential Reasoning Learning (DRL), a framework that improves clinical agents by learning from reasoning discrepancies. From…

Artificial Intelligence · Computer Science 2026-02-11 Jinsong Liu , Yuhang Jiang , Ramayya Krishnan , Rema Padman , Yiye Zhang , Jiang Bian

Alzheimer's disease (AD) diagnosis requires integrating neuroimaging with heterogeneous clinical evidence and reasoning under established criteria, yet most multimodal models remain opaque and weakly guideline-aligned. We present…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Qiuhui Chen , Yushan Deng , Xuancheng Yao , Yi Hong

Large language models (LLMs) have demonstrated remarkable capabilities in various domains, including radiology report generation. Previous approaches have attempted to utilize multimodal LLMs for this task, enhancing their performance…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Wenjun Hou , Yi Cheng , Kaishuai Xu , Heng Li , Yan Hu , Wenjie Li , Jiang Liu

Rare diseases affect hundreds of millions of people worldwide but are hard to detect since they have extremely low prevalence rates (varying from 1/1,000 to 1/200,000 patients) and are massively underdiagnosed. How do we reliably detect…

Machine Learning · Computer Science 2019-12-02 Limeng Cui , Siddharth Biswal , Lucas M. Glass , Greg Lever , Jimeng Sun , Cao Xiao

Retrieval-Augmented Generation (RAG) is widely employed to mitigate risks such as hallucinations and knowledge obsolescence in medical question answering, yet its predominantly single-round, static retrieval paradigm misaligns with the…

Computation and Language · Computer Science 2026-05-19 Yongfeng Huang , Ruiying Chen , James Cheng

Identifying the appropriate regulatory standard applicability remains a critical yet understudied challenge in medical device compliance, frequently necessitating expert interpretation of fragmented and heterogeneous documentation across…

Artificial Intelligence · Computer Science 2025-06-24 Yu Han , Aaron Ceross , Jeroen H. M. Bergmann

Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…

Computation and Language · Computer Science 2026-03-25 Wenhao Wu , Zhentao Tang , Yafu Li , Shixiong Kai , Mingxuan Yuan , Chunlin Chen , Zhi Wang

Modern large-scale recommender systems employ multi-stage ranking funnel (Retrieval, Pre-ranking, Ranking) to balance engagement and computational constraints (latency, CPU). However, the initial retrieval stage, often relying on efficient…

Information Retrieval · Computer Science 2025-06-10 Amit Jaspal , Qian Dang , Ajantha Ramineni

Large language models equipped with retrieval-augmented generation (RAG) represent a burgeoning field aimed at enhancing answering capabilities by leveraging external knowledge bases. Although the application of RAG with language-only…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Cheng Tan , Jingxuan Wei , Linzhuang Sun , Zhangyang Gao , Siyuan Li , Bihui Yu , Ruifeng Guo , Stan Z. Li

Missed and delayed diagnosis remains a major challenge in rare disease care. At the initial clinical encounters, physicians assess rare disease risk using only limited information under high uncertainty. When high-risk patients are not…

Artificial Intelligence · Computer Science 2026-01-27 Xi Chen , Hongru Zhou , Huahui Yi , Shiyu Feng , Hanyu Zhou , Tiancheng He , Mingke You , Li Wang , Qiankun Li , Kun Wang , Weili Fu , Kang Li , Jian Li

Retrieving visual and textual information from medical literature and hospital records can enhance diagnostic accuracy for clinical image interpretation. However, multimodal retrieval-augmented diagnosis is highly challenging. We explore a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nir Mazor , Tom Hope