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Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

Methodology · Statistics 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

Functional connectivity (FC) has been widely used to study brain network interactions underlying the emerging cognition and behavior of an individual. FC is usually defined as the correlation or partial correlation between brain regions.…

Applications · Statistics 2020-10-27 Gemeng Zhang , Aiying Zhang , Biao Cai , Zhuozhuo Tu , Vince D. Calhoun , Yu-Ping Wang

Fundus image segmentation on unseen domains is challenging, especially for the over-parameterized deep models trained on the small medical datasets. To address this challenge, we propose a method named Adaptive Feature-fusion Neural Network…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Jiyuan Zhong , Hu Ke , Ming Yan

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

Machine Learning · Computer Science 2016-11-15 Ehsan Hosseini-Asl , Robert Keynto , Ayman El-Baz

Traditional causal connectivity methods in task-based and resting-state functional magnetic resonance imaging (fMRI) face challenges in accurately capturing directed information flow due to their sensitivity to noise and inability to model…

Neurons and Cognition · Quantitative Biology 2025-04-03 Boseong Kim , Debashis Das Chakladar , Haejun Chung , Ikbeom Jang

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Deep learning methods are increasingly being used with neuroimaging data like structural and function magnetic resonance imaging (MRI) to predict the diagnosis of neuropsychiatric and neurological disorders. For psychiatric disorders in…

Neurons and Cognition · Quantitative Biology 2019-07-03 Ahmed El Gazzar , Leonardo Cerliani , Guido van Wingen , Rajat Mani Thomas

Resting-state functional magnetic resonance imaging (rs-fMRI) offers a non-invasive approach to examining abnormal brain connectivity associated with brain disorders. Graph neural network (GNN) gains popularity in fMRI representation…

Quantitative Methods · Quantitative Biology 2023-08-22 Junhao Zhang , Qianqian Wang , Xiaochuan Wang , Lishan Qiao , Mingxia Liu

Deep learning models based on resting-state functional magnetic resonance imaging (rs-fMRI) have been widely used to diagnose brain diseases, particularly autism spectrum disorder (ASD). Existing studies have leveraged the functional…

Machine Learning · Computer Science 2023-10-06 Wonsik Jung , Eunjin Jeon , Eunsong Kang , Heung-Il Suk

Functional connectivity (FC) derived from resting-state fMRI is widely used to characterize large-scale brain network alterations in neurological and psychiatric disorders. However, FC construction critically depends on the choice of brain…

Neurons and Cognition · Quantitative Biology 2026-05-11 Minheng Chen , Chao Cao , Jing Zhang , Tianming Liu , Dajiang Zhu

Alzheimer's disease (AD) is a common neurodegenerative disease among the elderly. Early prediction and timely intervention of its prodromal stage, mild cognitive impairment (MCI), can decrease the risk of advancing to AD. Combining…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Xiangyang Hu , Xiangyu Shen , Yifei Sun , Xuhao Shan , Wenwen Min , Liyilei Su , Xiaomao Fan , Ahmed Elazab , Ruiquan Ge , Changmiao Wang , Xiaopeng Fan

Large, open-source consortium datasets have spurred the development of new and increasingly powerful machine learning approaches in brain connectomics. However, one key question remains: are we capturing biologically relevant and…

Depression and Attention Deficit Hyperactivity Disorder (ADHD) stand out as the common mental health challenges today. In affective computing, speech signals serve as effective biomarkers for mental disorder assessment. Current research,…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-05 Shuanglin Li , Siyang Song , Rajesh Nair , Syed Mohsen Naqvi

Tremendous recent literature show that associations between different brain regions, i.e., brain connectivity, provide early symptoms of neurological disorders. Despite significant efforts made for graph neural network (GNN) techniques,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Xin Ma , Guorong Wu , Seong Jae Hwang , Won Hwa Kim

Graph Neural Networks have recently become a prevailing paradigm for various high-impact graph analytical problems. Existing efforts can be mainly categorized as spectral-based and spatial-based methods. The major challenge for the former…

Machine Learning · Computer Science 2022-02-22 Yushun Dong , Kaize Ding , Brian Jalaian , Shuiwang Ji , Jundong Li

A great improvement to the insight on brain function that we can get from fMRI data can come from effective connectivity analysis, in which the flow of information between even remote brain regions is inferred by the parameters of a…

Neurons and Cognition · Quantitative Biology 2012-08-21 G. Wu , W. Liao , S. Stramaglia , J. Ding , H. Chen , D. Marinazzo

Recently, the potential of dynamic brain networks as a neuroimaging biomarkers for mental illnesses is being increasingly recognized. However, there are several unmet challenges in developing such biomarkers, including the need for methods…

Neurons and Cognition · Quantitative Biology 2019-10-10 Suprateek Kundu , Jin Ming , Jennifer Stevens

Focal cortical dysplasia (FCD) is a leading cause of drug-resistant focal epilepsy, which can be cured by surgery. These lesions are extremely subtle and often missed even by expert neuroradiologists. "Ground truth" manual lesion masks are…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Hannah Spitzer , Mathilde Ripart , Abdulah Fawaz , Logan Z. J. Williams , MELD project , Emma Robinson , Juan Eugenio Iglesias , Sophie Adler , Konrad Wagstyl

Brain functional connectivity (FC) reveals biomarkers for identification of various neuropsychiatric disorders. Recent application of deep neural networks (DNNs) to connectome-based classification mostly relies on traditional convolutional…

Neurons and Cognition · Quantitative Biology 2024-01-31 Fuad Noman , Chee-Ming Ting , Hakmook Kang , Raphael C. -W. Phan , Brian D. Boyd , Warren D. Taylor , Hernando Ombao

Significant progress has been made using fMRI to characterize the brain changes that occur in ASD, a complex neuro-developmental disorder. However, due to the high dimensionality and low signal-to-noise ratio of fMRI, embedding informative…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Xiaoxiao Li , Nicha C. Dvornek , Juntang Zhuang , Pamela Ventola , James Duncan
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