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In this study, we proposed and validated a multi-atlas guided 3D fully convolutional network (FCN) ensemble model (M-FCN) for segmenting brain regions of interest (ROIs) from structural magnetic resonance images (MRIs). One major limitation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Jiong Wu , Xiaoying Tang

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by atypical brain connectivity. One of the crucial steps in addressing ASD is its early detection. This study introduces a novel computational framework that…

Applications · Statistics 2026-03-31 Abigail Kelly , Ramchandra Rimal , Arpan Sainju

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Multimodal medical image fusion helps in combining contrasting features from two or more input imaging modalities to represent fused information in a single image. One of the pivotal clinical applications of medical image fusion is the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Nishant Kumar , Nico Hoffmann , Martin Oelschlägel , Edmund Koch , Matthias Kirsch , Stefan Gumhold

The estimation of time-varying networks for functional Magnetic Resonance Imaging (fMRI) data sets is of increasing importance and interest. In this work, we formulate the problem in a high-dimensional time series framework and introduce a…

Applications · Statistics 2016-06-24 Ivor Cribben , Yi Yu

Neuropsychiatric disorders, such as Alzheimer's disease (AD), depression, and autism spectrum disorder (ASD), are characterized by linguistic and acoustic abnormalities, offering potential biomarkers for early detection. Despite the promise…

Computation and Language · Computer Science 2025-12-25 Zhongren Dong , Haotian Guo , Weixiang Xu , Huan Zhao , Zixing Zhang

Using multimodal neuroimaging data to characterize brain network is currently an advanced technique for Alzheimer's disease(AD) Analysis. Over recent years the neuroimaging community has made tremendous progress in the study of…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Junren Pan , Baiying Lei , Yanyan Shen , Yong Liu , Zhiguang Feng , Shuqiang Wang

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

Neurons and Cognition · Quantitative Biology 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Since Huang proposed the Empirical Mode Decomposition (EMD) in 1998, mode decomposition has been widely studied, but EMD and relative developed algorithms are still generally lack of adaptability and mathematical theory. This paper propose…

Signal Processing · Electrical Eng. & Systems 2021-08-27 Hu Yiting , Wu Zhuangzhi

Functional near-infrared spectroscopy (fNIRS) is a non-intrusive way to measure cortical hemodynamic activity. Predicting cognitive workload from fNIRS data has taken on a diffuse set of methods. To be applicable in real-world settings,…

Machine Learning · Computer Science 2024-05-02 Jiyang Wang , Ayse Altay , Senem Velipasalar

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

Optimization and Control · Mathematics 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Building comprehensive brain connectomes has proved of fundamental importance in resting-state fMRI (rs-fMRI) analysis. Based on the foundation of brain network, spatial-temporal-based graph convolutional networks have dramatically improved…

Machine Learning · Computer Science 2023-12-19 Rui Yang , Wenrui Dai , Huajun She , Yiping P. Du , Dapeng Wu , Hongkai Xiong

The automatic detection of atrial fibrillation based on electrocardiograph (ECG) signals has received wide attention both clinically and practically. It is challenging to process ECG signals with cyclical pattern, varying length and…

Machine Learning · Computer Science 2023-02-10 Yifan Sun , Jingyan Shen , Yunfan Jiang , Zhaohui Huang , Minsheng Hao , Xuegong Zhang

Alzheimer's disease (AD) is a neurodegenerative disorder that affects more than seven million people in the United States alone. AD currently has no cure, but there are ways to potentially slow its progression if caught early enough. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Mahdi Moghaddami , Mohammad-Reza Siadat , Austin Toma , Connor Laming , Huirong Fu

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

Visual image reconstruction from functional Magnetic Resonance Imaging (fMRI) is a fundamental task in brain decoding, providing a crucial pathway for understanding human perceptual mechanisms and developing advanced brain-computer…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Yudan Ren , Pengcheng Shi , Zihan Ma , Xiaowei He , Xiao Li

Resting-state fMRI (rs-fMRI) functional connectivity (FC) analysis provides valuable insights into the relationships between different brain regions and their potential implications for neurological or psychiatric disorders. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Xiatian Zhang , Sisi Zheng , Hubert P. H. Shum , Haozheng Zhang , Nan Song , Mingkang Song , Hongxiao Jia
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