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Related papers: Quantum-elevated Chiral Discrimination for Bio-mol…

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We propose a method to realize enantiodiscrimination of chiral molecules based on quantum correlation function in a driven cavity-molecule system, where the chiral molecule is coupled with a quantized cavity field and two classical light…

Quantum Physics · Physics 2022-08-12 Fen Zou , Yu-Yuan Chen , Bo Liu , Yong Li

Chiral discrimination that is efficient to tiny amounts of chiral substances, especially at the single-molecule level, is highly demanded. Here, we propose a single-shot nondestructive quantum sensing method addressing such an issue. Our…

Quantum Physics · Physics 2023-10-05 Chong Ye , Yifan Sun , Yong Li , Xiangdong Zhang

A novel optical method for distinguishing chiral molecules is proposed and validated within a quantum simulator employing a trapped-ion qudit. This approach correlates the sign disparity of the dipole moment of chiral molecules with…

Quantum Physics · Physics 2024-03-11 Teng Liu , Fa Zhao , Pengfei Lu , Qifeng Lao , Min Ding , Ji Bian , Feng Zhu , Le Luo

This work presents a quantum-limited optomechanical sensing platform for real-time detection and discrimination of chiral molecules, based on a multilayer hybrid plasmonic-mechanical resonator. Leveraging quantum zero-point motion and…

Optics · Physics 2025-07-29 Giuseppina Simone

Strong light-matter coupling in chiral cavities has been proposed as an effective way to selectively interact with an enantiomer that shares the same handedness as the cavity's chiral mode. We show that surface plasmons supported by a…

Enantiodetection of chiral molecules is important to pharmaceutical drug production, chemical reaction control, and biological function designs. Traditional optical methods of enantiodetection rely on the weak magnetic-dipole or…

Chemical Physics · Physics 2022-09-14 Mao-Rui Cai , Chong Ye , Hui Dong , Yong Li

A new scheme for enantiomer differentiation of chiral molecules using a pair of linearly polarized intense ultrashort laser pulses with skewed mutual polarization is presented. The technique relies on the fact that the off-diagonal…

Chemical Physics · Physics 2017-05-04 Andrey Yachmenev , Sergei N. Yurchenko

The most important problem of spectroscopic chiral analysis is the inherently weak chiral signals are easily overwhelmed by the environment noises. Enormous efforts had been spent to overcome this problem by enhancing the symmetry break in…

Quantum Physics · Physics 2023-10-05 Chong Ye , Yifan Sun , Xiangdong Zhang

Developing effective methods to measure the enantiomeric excess of the chiral mixture is one of the major topics in chiral molecular researches, yet remains challenging. Enantiodetection method via two-dimensional (2D) spectroscopy based on…

Chemical Physics · Physics 2023-05-05 Mao-Rui Cai , Chong Ye , Yong Li , Hui Dong

Nanophotonic platforms in theory uniquely enable < femtomoles of chiral biological and pharmaceutical molecules to be detected, through the highly localised changes in the chiral asymmetries of the near-fields that they induce. However,…

Enantioselective photochemistry provides access to unique molecular structures and functions, with deep implications for fundamental science and industrial applications. Current methods for highly enantioselective photochemistry critically…

Chemical Physics · Physics 2025-03-07 Andrés Ordóñez , Patricia Vindel-Zandbergen , David Ayuso

Particular advantages of chiral molecules for direct detection of the time-dependence of pseudoscalar and the timelike-component of pseudovector cosmic fields are highlighted. Such fields are invoked in different models for cold dark matter…

High Energy Physics - Phenomenology · Physics 2020-09-23 Konstantin Gaul , Mikhail G. Kozlov , Timur A. Isaev , Robert Berger

The measurement of circular dichroism (CD) has widely been exploited to distinguish the different enantiomers of chiral structures. It has been applied to natural materials (e.g. molecules) as well as to artificial materials (e.g.…

Chiral near fields possessing enhanced asymmetry (superchirality), created by the interaction of light with (chiral) nanostructures, potentially provide a route to novel sensing and metrology technologies for biophysical applications.…

The development of efficient techniques to distinguish mirror images of chiral molecules (enantiomers) is very important in both chemistry and physics. Enantiomers share most molecular properties except, for instance, the absorption of…

Chemical Physics · Physics 2023-07-11 Rosario R. Riso , Laura Grazioli , Enrico Ronca , Tommaso Giovannini , Henrik Koch

Chirality is ubiquitous in nature and fundamental in science, from particle physics to metamaterials.The most established technique of chiral discrimination - photoabsorption circular dichroism - relies on the magnetic properties of a…

The detection and discrimination of molecular chirality are essential for advancing pharmaceutical and biological applications. While nanophotonic platforms offer a route to enhance chiral light-matter interactions, existing device concepts…

Optics · Physics 2025-11-21 Zhongjun Jiang , Soyaib Sohag , You Zhou

Biologically important molecules span a size range from very large biomacromolecules, such as proteins to small metabolite molecules. Consequently, spectroscopic techniques which can detect and characterize the structure of inherently…

Distinguishing between enantiomers is crucial in the study of chiral molecules in chemistry and pharmacology. Many optical approaches rely on enantiospecific cyclic electric-dipole transitions induced by three microwave or laser beams.…

Quantum Physics · Physics 2025-12-11 Fen Zou , Yong Li , Peng Zhang

Chiral nanophotonic platforms provide a means of creating near fields with both enhanced asymmetric properties and intensities. They can be exploited for optical measurements that allow enantiomeric discrimination at detection levels…

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