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Related papers: Quantum-elevated Chiral Discrimination for Bio-mol…

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We investigate enantiodetection for both a single cyclic three-level chiral molecule and finite ensembles of such molecules by monitoring the steady-state intracavity photon number in a cavity-QED platform. Our scheme exploits the intrinsic…

Quantum Physics · Physics 2025-11-14 Xiang Guo , Xiaojun Zhang , Yong Li , Zhihai Wang

Nonlinear optical processes are used in biological microscopy to surpass the diffraction limit on resolution, image deeper into brain tissues, and identify biomolecules without exogenous labels. These techniques typically require high…

Chiral molecule sensing is currently performed using chromatography, electrophoresis, enzymatic-assays, mass spectrometry, and chiroptical sensing techniques. Currently polarimetry is the only method having in-vivo sensing capabilities,…

Medical Physics · Physics 2024-01-22 Swathi Padmanabhan , Jaya Prakash

Resonance energy transfer between chiral molecules can be used to discriminate between different enantiomers. The transfer rate between chiral molecules consists of a non-discriminatory and discriminatory parts. We derive these two rate…

Quantum Physics · Physics 2023-03-29 Janine Christine Franz , Stefan Yoshi Buhmann , A. Salam

Chirality discrimination is of a fundamental interest in biology, chemistry, and metamaterial studies. In optics, near-field plasmon-resonance spectroscopy with superchiral probing fields is effectively applicable for analyses of large…

Materials Science · Physics 2016-05-03 E. Hollander , E. O. Kamenetskii , R. Shavit

Enantiodetection is an important and challenging task across natural science. Nowadays, some chiroptical methods of enantiodetection based on decoherence-free cyclic three-level models of chiral molecules can reach the ultimate limit of the…

Quantum Physics · Physics 2022-11-29 Chong Ye , Xiaowei Mu , Yifan Sun , Libin Fu , Xiangdong Zhang

Sensing and discriminating between enantiomers of chiral molecules remains a significant challenge in the design of sensor platforms. In the case of chemoresistive sensors, where detection relies on changes in electrical response upon…

The differential response of chiral molecules to incident left- and right- handed circularly polarized light is used for sensing the handedness of molecules. Currently, significant effort is directed towards enhancing weak differential…

We derive here a new highly selective photoelectron-based chirality-sensing technique that utilizes 'locally-chiral' laser pulses. We show that this approach results in strong chiral discrimination, where the standard forwards/backwards…

Chemical Physics · Physics 2021-07-14 Ofer Neufeld , Hannes Hübener , Angel Rubio , Umberto De Giovannini

We discuss how tensorial observables, available in photoelectron angular distributions resulting from interaction between isotropic chiral samples and cross polarized $\omega$-$2\omega$ bichromatic fields, allow for chiral discrimination…

Atomic Physics · Physics 2022-06-28 Andres F. Ordonez , Olga Smirnova

The practical applications of chiral discrimination are usually limited by the weak chiral response of enantiomers and the high complexity of detection methods. Here, we propose to use the C lines (i.e., lines of polarization singularities)…

Optics · Physics 2022-03-22 Shiqi Jia , Jie Peng , Yuqiong Cheng , Shubo Wang

We propose to discriminate chiral molecules by combining one- and two-photon processes in a closed-loop configuration. The one-photon-coupling intrinsic {\pi}-phase difference between two enantiomers leads to their different superposition…

Quantum Physics · Physics 2020-02-20 Jin-Lei Wu , Yan Wang , Jie Song , Yan Xia , Shi-Lei Su , Yong-Yuan Jiang

We propose an approach to sensitively probe the chirality of molecules by measuring their coherent optical absorption spectra. It is shown that quantum dynamics of the cyclic three-level chiral molecules driven by appropriately-designed…

Quantum Physics · Physics 2015-05-28 W. Z. Jia , L. F. Wei

The chiral state of a molecule plays a crucial role in molecular recognition and biochemical reactions. Because of this and owing to the fact that most modern drugs are chiral, the sensitive and reliable detection of the chirality of…

Mesoscale and Nanoscale Physics · Physics 2019-04-30 Luisa M. Kneer , Eva-Maria Roller , Lucas V. Besteiro , Robert Schreiber , Alexander O. Govorov , Tim Liedl

Light is one of the most powerful and precise tools allowing us to control, shape and create new phases of matter. In this task, the magnetic component of a light wave has so far played a unique role in defining the wave's helicity, but its…

A recently proposed theory of chiral discrimination in NMR spectroscopy based on the detection of a molecular electric polarization $\mathbf{P}$ rotating in a plane perpendicular to the NMR magnetic field [A. D. Buckingham, J. Chem. Phys.…

Chemical Physics · Physics 2016-04-26 Alessandro Soncini , Simone Calvello

Identifying the handedness of chiral molecules is of fundamental importance in chemistry, biology, pharmacy, and medicine. Nanophotonic structures allow us to control light at the nanoscale and offer powerful tools for chiral sensing,…

Circular dichroism spectroscopy is an essential technique for understanding molecular structure and magnetic materials, but spatial resolution is limited by the wavelength of light, and sensitivity sufficient for single-molecule…

Molecular matter-wave interferometry enables novel strategies for manipulating the internal mechanical motion of complex molecules. Here, we show how chiral molecules can be prepared in a quantum superposition of two enantiomers by…

Quantum Physics · Physics 2021-09-22 Benjamin A. Stickler , Mira Diekmann , Robert Berger , Daqing Wang

We propose a theoretical method for enantio-discrimination based on the light deflection effect in four-level models of chiral molecules. This four-level model consists of a cyclic three-level subsystem coupled by three strong driving…

Optics · Physics 2020-08-12 Yu-Yuan Chen , Chong Ye , Quansheng Zhang , Yong Li