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Generating large-scale, physically consistent AC Optimal Power Flow (ACOPF) datasets is essential for modern data-driven power system applications. The central challenge lies in balancing solution accuracy with computational efficiency.…

Systems and Control · Electrical Eng. & Systems 2026-02-04 Shashank Shekhar , Abhinav Karn , Kris Keshav , Shivam Bansal , Parikshit Pareek

We study an inverse design problem for the linear multiple fragmentation equation arising in particle dynamics. Our objective is to reconstruct an unknown initial size distribution that evolves, under a prescribed fragmentation law, into a…

Optimization and Control · Mathematics 2026-02-20 Arijit Das

Shape optimization approaches to inverse design offer low-dimensional, physically-guided parameterizations of structures by representing them as combinations of shape primitives. However, on discretized rectilinear simulation grids,…

Computational Engineering, Finance, and Science · Computer Science 2023-11-13 Sean Hooten , Peng Sun , Liron Gantz , Marco Fiorentino , Raymond G. Beausoleil , Thomas Van Vaerenbergh

In clinical diagnostics and research involving histopathology, formalin fixed paraffin embedded (FFPE) tissue is almost universally favored for its superb image quality. However, tissue processing time (more than 24 hours) can slow…

Image and Video Processing · Electrical Eng. & Systems 2021-08-25 Kianoush Falahkheirkhah , Tao Guo , Michael Hwang , Pheroze Tamboli , Christopher G Wood , Jose A Karam , Kanishka Sircar , Rohit Bhargava

The aggregated unfitted finite element method (AgFEM) is a methodology recently introduced in order to address conditioning and stability problems associated with embedded, unfitted, or extended finite element methods. The method is based…

Numerical Analysis · Computer Science 2019-08-20 Francesc Verdugo , Alberto F. Martín , Santiago Badia

For nonlinear multispectral computed tomography (CT), accurate and fast image reconstruction is challenging when the scanning geometries under different X-ray energy spectra are inconsistent or mismatched. Motivated by this, we propose an…

Numerical Analysis · Mathematics 2025-07-28 Yu Gao , Chong Chen

Few-shot industrial anomaly detection (FS-IAD) presents a critical challenge for practical automated inspection systems operating in data-scarce environments. While existing approaches predominantly focus on deriving prototypes from limited…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Long Tian , Yufei Li , Yuyang Dai , Wenchao Chen , Xiyang Liu , Bo Chen

Predicting a structure of an antibody from its sequence is important since it allows for a better design process of synthetic antibodies that play a vital role in the health industry. Most of the structure of an antibody is conservative.…

Biomolecules · Quantitative Biology 2021-12-23 Natalia Zenkova , Ekaterina Sedykh , Tatiana Shugaeva , Vladislav Strashko , Timofei Ermak , Aleksei Shpilman

Motion artifact is a major challenge in magnetic resonance imaging (MRI) that severely degrades image quality, reduces examination efficiency, and makes accurate diagnosis difficult. However, previous methods often relied on implicit models…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Jiandong Su , Kun Shang , Dong Liang

For stochastic systems with discrete time delay, the Fokker-Planck equation (FPE) of the one-time probability density function (PDF) does not provide a complete, self-contained probabilistic description. It explicitly involves the two-time…

Statistical Mechanics · Physics 2019-10-02 Sarah A. M. Loos , Sabine H. L. Klapp

Generating high-fidelity and biologically plausible synthetic single-cell RNA sequencing (scRNA-seq) data, especially with conditional control, is challenging due to its high dimensionality, sparsity, and complex biological variations.…

Machine Learning · Computer Science 2025-06-17 Lorenzo Bini , Stephane Marchand-Maillet

In this work, we address the challenging task of 3D object recognition without the reliance on real-world 3D labeled data. Our goal is to predict the 3D shape, size, and 6D pose of objects within a single RGB-D image, operating at the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Mayank Lunayach , Sergey Zakharov , Dian Chen , Rares Ambrus , Zsolt Kira , Muhammad Zubair Irshad

To generate drug molecules of desired properties with computational methods is the holy grail in pharmaceutical research. Here we describe an AI strategy, retro drug design, or RDD, to generate novel small molecule drugs from scratch to…

Biomolecules · Quantitative Biology 2021-05-12 Yuhong Wang , Sam Michael , Ruili Huang , Jinghua Zhao , Katlin Recabo , Danielle Bougie , Qiang Shu , Paul Shinn , Hongmao Sun

Rare-disease diagnosis remains one of the most pressing challenges in digital health, hindered by extreme data scarcity, privacy concerns, and the limited resources of edge devices. This paper proposes the Adaptive Federated Few-Shot…

Artificial Intelligence · Computer Science 2025-10-02 Aueaphum Aueawatthanaphisut

Limited-angle computerized tomography stands for one of the most difficult challenges in imaging. Although it opens the way to faster data acquisition in industry and less dangerous scans in medicine, standard approaches, such as the…

Image and Video Processing · Electrical Eng. & Systems 2025-10-07 Bernadette Hahn , Gael Rigaud , Richard Schmähl

For explainable fault detection and classification (FDC), this paper proposes a unified framework, ABIGX (Adversarial fault reconstruction-Based Integrated Gradient eXplanation). ABIGX is derived from the essentials of previous successful…

Machine Learning · Computer Science 2023-11-10 Yue Zhuo , Jinchuan Qian , Zhihuan Song , Zhiqiang Ge

The PC algorithm allows investigators to estimate a complete partially directed acyclic graph (CPDAG) from a finite dataset, but few groups have investigated strategies for estimating and controlling the false discovery rate (FDR) of the…

Machine Learning · Statistics 2017-05-11 Eric V. Strobl , Peter L. Spirtes , Shyam Visweswaran

This work is concerned with solving high-dimensional Fokker-Planck equations with the novel perspective that solving the PDE can be reduced to independent instances of density estimation tasks based on the trajectories sampled from its…

Numerical Analysis · Mathematics 2023-12-13 Xun Tang , Lexing Ying

Antibody design is valuable for therapeutic usage and biological research. Existing deep-learning-based methods encounter several key issues: 1) incomplete context for Complementarity-Determining Regions (CDRs) generation; 2) incapability…

Biomolecules · Quantitative Biology 2023-03-31 Xiangzhe Kong , Wenbing Huang , Yang Liu

Earth observation foundation models encode land surface information into dense embedding vectors, yet the geometric structure of these representations and its implications for downstream reasoning remain underexplored. We characterize the…

Computation and Language · Computer Science 2026-04-22 Mashrekur Rahman , Samuel J. Barrett , Christina Last