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This paper proposes a numerical method, termed PosDiv-CDG, that provably preserves both positivity and the globally divergence-free (DF) condition at arbitrarily high order in multiple dimensions. It resolves the fundamental structural…

Numerical Analysis · Mathematics 2025-08-13 Ruifang Yan , Huihui Cao , Kailiang Wu

Solving medical imaging data scarcity through semantic image generation has attracted growing attention in recent years. However, existing generative models mainly focus on synthesizing whole-organ or large-tissue structures, showing…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Jiahao Xia , Yutao Hu , Yaolei Qi , Zhenliang Li , Wenqi Shao , Junjun He , Ying Fu , Longjiang Zhang , Guanyu Yang

Fractional differential equations (FDEs) describe subdiffusion behavior of dynamical systems. Its non-local structure requires taking into account the whole evolution history during the time integration, which then possibly causes…

Numerical Analysis · Mathematics 2022-02-17 Ustim Khristenko , Barbara Wohlmuth

Boundary Representation (B-Rep) is the widely adopted standard in Computer-Aided Design (CAD) and manufacturing. However, generative modeling of B-Reps remains a formidable challenge due to their inherent heterogeneity as geometric cell…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Junran Lu , Yuanqi Li , Hengji Li , Jie Guo , Yanwen Guo

Applications that involve supervised training require paired images. Researchers of single image super-resolution (SISR) create such images by artificially generating blurry input images from the corresponding ground truth. Similarly we can…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Nao Takano , Gita Alaghband

In this paper, we introduce second order and fourth order space discretization via finite difference implementation of the finite element method for solving Fokker-Planck equations associated with irreversible processes. The proposed…

Numerical Analysis · Mathematics 2023-10-12 Chen Liu , Yuan Gao , Xiangxiong Zhang

Breakthroughs in high-accuracy protein structure prediction, such as AlphaFold, have established receptor-based molecule design as a critical driver for rapid early-phase drug discovery. However, most approaches still struggle to balance…

Biomolecules · Quantitative Biology 2025-06-18 Dong Xu , Zhangfan Yang , Ka-chun Wong , Zexuan Zhu , Jiangqiang Li , Junkai Ji

The steep rise in availability and usage of high-throughput technologies in biology brought with it a clear need for methods to control the False Discovery Rate (FDR) in multiple tests. Benjamini and Hochberg (BH) introduced in 1995 a…

Methodology · Statistics 2011-08-11 Amit Zeisel , Or Zuk , Eytan Domany

The design of \emph{de novo} functional proteins that bind specific ligand molecules is paramount in therapeutics and bio-engineering. A critical yet formidable task in this endeavor is the design of the protein pocket, which is the cavity…

Biomolecules · Quantitative Biology 2023-10-23 Zaixi Zhang , Zepu Lu , Zhongkai Hao , Marinka Zitnik , Qi Liu

Developing bioactive molecules remains a central, time- and cost-heavy challenge in drug discovery, particularly for novel targets lacking structural or functional data. Pharmacophore modeling presents an alternative for capturing the key…

Machine Learning · Computer Science 2025-05-16 Amira Alakhdar , Barnabas Poczos , Newell Washburn

In this paper we study the dynamics of a fast-slow Fokker-Planck partial differential equation (PDE) viewed as the evolution equation for the density of a multiscale planar stochastic differential equation (SDE). Our key focus is on the…

Analysis of PDEs · Mathematics 2025-02-03 Christian Kuehn , Jan-Eric Sulzbach

Fair principal component analysis (FPCA), a ubiquitous dimensionality reduction technique in signal processing and machine learning, aims to find a low-dimensional representation for a high-dimensional dataset in view of fairness. The FPCA…

Optimization and Control · Mathematics 2023-12-27 Meng Xu , Bo Jiang , Wenqiang Pu , Ya-Feng Liu , Anthony Man-Cho So

Camera-based multi-view 3D detection is crucial for autonomous driving. PETR and its variants (PETRs) excel in benchmarks but face deployment challenges due to high computational cost and memory footprint. Quantization is an effective…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Jiangyong Yu , Changyong Shu , Sifan Zhou , Zichen Yu , Xing Hu , Yan Chen , Dawei Yang

Camera-based multi-view 3D detection is crucial for autonomous driving. PETR and its variants (PETRs) excel in benchmarks but face deployment challenges due to high computational cost and memory footprint. Quantization is an effective…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Jiangyong Yu , Changyong Shu , Sifan Zhou , Zichen Yu , Xing Hu , Yan Chen , Dawei Yang

Existing fine-grained image retrieval (FGIR) methods predominantly rely on supervision from predefined categories to learn discriminative representations for retrieving fine-grained objects. However, they inadvertently introduce…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Shijie Wang , Jian Shi , Haojie Li

Principal Component Analysis (PCA) is a foundational technique in machine learning for dimensionality reduction of high-dimensional datasets. However, PCA could lead to biased outcomes that disadvantage certain subgroups of the underlying…

Machine Learning · Computer Science 2025-03-04 Junhui Shen , Aaron J. Davis , Ding Lu , Zhaojun Bai

Structural topology optimization, which aims to find the optimal physical structure that maximizes mechanical performance, is vital in engineering design applications in aerospace, mechanical, and civil engineering. Generative adversarial…

Machine Learning · Computer Science 2022-12-07 François Mazé , Faez Ahmed

We study the gradient flow structure and long-time behavior of Fokker-Planck equations (FPE) on infinite graphs, along with a Talagrand-type inequality in this setting. We begin by constructing an infinite-dimensional Hilbert manifold…

Analysis of PDEs · Mathematics 2025-11-18 Jose A. Carrillo , Xinyu Wang

Along with current multi-scale based detectors, Feature Aggregation and Enhancement (FAE) modules have shown superior performance gains for cutting-edge object detection. However, these hand-crafted FAE modules show inconsistent…

Computer Vision and Pattern Recognition · Computer Science 2022-01-27 Jian Li , Bin Zhang , Yabiao Wang , Ying Tai , ZhenYu Zhang , Chengjie Wang , Jilin Li , Xiaoming Huang , Yili Xia

The Rosenbluth-Fokker-Planck (RFP) equation describes Coulomb collisional dynamics within and across species in plasmas. It belongs to the broader class of anisotropic-diffusion-advection equations, whose numerical approximation is…

Numerical Analysis · Mathematics 2026-01-15 Hamad El Kahza , Luis Chacón , William Taitano , Jingmei Qiu , Jingwei Hu
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