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While the Artificial Pancreas is effective in regulating the blood glucose in the safe range of 70-180 mg/dl in type 1 diabetic patients, the high intra-patient variability, as well as exogenous meal disturbances, poses a serious challenge.…

Systems and Control · Electrical Eng. & Systems 2022-06-30 Bhabani Shankar Dey , Anirudh Nath , Abhilash Patel , Indra Narayan Kar

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

Machine Learning · Computer Science 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…

Machine Learning · Computer Science 2026-01-22 Giorgia Rigamonti , Mirko Paolo Barbato , Davide Marelli , Paolo Napoletano

Missing data is a ubiquitous problem. It is especially challenging in medical settings because many streams of measurements are collected at different - and often irregular - times. Accurate estimation of those missing measurements is…

Machine Learning · Computer Science 2017-11-27 Jinsung Yoon , William R. Zame , Mihaela van der Schaar

Type 2 diabetes mellitus (T2DM) is one of the most common diseases and a leading cause of death. The problem of early diagnosis of T2DM is challenging and necessary to prevent serious complications. This study proposes a novel neural…

Machine Learning · Computer Science 2023-01-20 Tayyab Nasir , Muhammad Kamran Malik

Personal health devices can enable continuous monitoring of health parameters. However, the benefit of these devices is often directly related to the frequency of use. Therefore, adherence to personal health devices is critical. This paper…

Computers and Society · Computer Science 2020-06-11 Sudip Vhaduri , Temiloluwa Prioleau

Managing Type 1 Diabetes (T1D) demands constant vigilance as individuals strive to regulate their blood glucose levels and avoid dysglycemia, including hyperglycemia and hypoglycemia. Despite advances in automated insulin delivery (AID)…

Machine Learning · Computer Science 2026-02-26 Saman Khamesian , Asiful Arefeen , Maria Adela Grando , Bithika M. Thompson , Hassan Ghasemzadeh

Background: Type 1 diabetes (T1D) has seen a rapid evolution in management technology and forms a useful case study for the future management of other chronic conditions. Further development of this management technology requires an…

Human-Computer Interaction · Computer Science 2025-07-25 Sam Gordon James , Miranda Elaine Glynis Armstrong , Aisling Ann O'Kane , Harry Emerson , Zahraa S. Abdallah

Data-driven models for glucose level forecast often do not provide meaningful insights despite accurate predictions. Yet, context understanding in medicine is crucial, in particular for diabetes management. In this paper, we introduce…

Machine Learning · Computer Science 2021-11-16 Quentin Blampey , Mehdi Rahim

A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…

Machine Learning · Computer Science 2023-03-09 Jakub J. Dylag

Type 1 Diabetes is a chronic autoimmune condition in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, resulting in little to no insulin production. Insulin helps glucose in your blood enter your…

Quantitative Methods · Quantitative Biology 2025-02-04 Soon Jynn Chu , Nalaka Amarasiri , Sandesh Giri , Priyata Kafle

This article compares ten recently proposed neural networks and proposes two ensemble neural network-based models for blood glucose prediction. All of them are tested under the same dataset, preprocessing workflow, and tools using the…

Quantitative Methods · Quantitative Biology 2021-09-07 Felix Tena , Oscar Garnica , Juan Lanchares , J. Ignacio Hidalgo

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

This study introduces a novel approach for early Type 2 Diabetes Mellitus (T2DM) risk prediction using a tabular transformer (TabTrans) architecture to analyze longitudinal patient data. By processing patients` longitudinal health records…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Sulaiman Khan , Md. Rafiul Biswas , Zubair Shah

Automatic classification of Diabetic Retinopathy (DR) can assist ophthalmologists in devising personalized treatment plans, making it a critical component of clinical practice. However, imbalanced data distribution in the dataset becomes a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Abdul Hannan , Zahid Mahmood , Rizwan Qureshi , Hazrat Ali

A deep learning network was used to predict future blood glucose levels, as this can permit diabetes patients to take action before imminent hyperglycaemia and hypoglycaemia. A sequential model with one long-short-term memory (LSTM) layer,…

Machine Learning · Computer Science 2018-09-12 Qingnan Sun , Marko V. Jankovic , Lia Bally , Stavroula G. Mougiakakou

Blood glucose simulation allows the effectiveness of type 1 diabetes (T1D) management strategies to be evaluated without patient harm. Deep learning algorithms provide a promising avenue for extending simulator capabilities; however, these…

Machine Learning · Computer Science 2023-10-24 Harry Emerson , Ryan McConville , Matthew Guy

Precise and timely forecasting of blood glucose levels is essential for effective diabetes management. While extensive research has been conducted on Type 1 diabetes mellitus, Type 2 diabetes mellitus (T2DM) presents unique challenges due…

Computational Engineering, Finance, and Science · Computer Science 2024-09-12 Yuyang Sun , Panagiotis Kosmas

Biosensor data has the potential ability to improve disease control and detection. However, the analysis of these data under free-living conditions is not feasible with current statistical techniques. To address this challenge, we introduce…

Applications · Statistics 2021-03-30 Marcos Matabuena , Alexander Petersen , Juan C. Vidal , Francisco Gude

People with Type 1 diabetes (T1D) require regular exogenous infusion of insulin to maintain their blood glucose concentration in a therapeutically adequate target range. Although the artificial pancreas and continuous glucose monitoring…

Signal Processing · Electrical Eng. & Systems 2020-09-08 Taiyu Zhu , Kezhi Li , Pau Herrero , Pantelis Georgiou