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Upright position CT scans make it possible for full-length-body imaging at conditions more relevant to daily situations, but the substantial weight of the upright CT scanners increases the risks to floor's stability and patients'safety.…

Medical Physics · Physics 2023-11-13 Tong Lin , Tianling Lyu , Zhan Wu , Yan Xi , Wentao Zhu , Yang Chen

Purpose: The importance of robust proton treatment planning to mitigate the impact of uncertainty is well understood. However, its computational cost grows with the number of uncertainty scenarios, prolonging the treatment planning process.…

Medical Physics · Physics 2023-05-01 Anqi Fu , Vicki T. Taasti , Masoud Zarepisheh

Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…

Medical Physics · Physics 2019-03-20 Monika Varga-Kofarago

Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient. The conversion from x-ray attenuation to proton stopping power in tissue…

While drastic improvements in CT technology have occurred in the past 25 years, spatial resolution is one area where progress has been limited until recently. New photon counting CT systems, are capable of much better spatial resolution…

Purpose: Recent work highlights the breadth of reported spin-lattice relaxation rates ($R_1$) for individual tissues. One potential source of variation is the protocol used to determine $R_1$. The methodological dependence of R1 and…

Medical Physics · Physics 2019-10-01 Christopher Jenkins , Ioannis Papadopoulos , S. M. Shermer

In this study, two proton beam delivery designs, passive scattering proton therapy (PSPT) and pencil beam scanning (PBS), were quantitatively compared in terms of dosimetric indices. The GATE Monte Carlo code was used to simulate the proton…

Medical Physics · Physics 2022-09-21 A. Asadi , A. Akhavanallaf , S. A. Hosseini , H. Zaidi

Electromagnetic tracking (EMT) shows great potential for automating implant reconstruction in brachytherapy. One of the challenges of this technology is that it does not intrinsically share the same reference frame as the patient's medical…

Objective: To propose a CBCT dose optimization method using readily available measurement equipment in radiation oncology departments. Approach: A 0.6cc air kerma (Kair) calibrated Farmer chamber measured Kair at isocenter for five default…

Medical Physics · Physics 2025-02-04 S. Gros , J. Bian , J. Jackson , M. Delafuente , H. Kang , W. Small , M. Mahesh

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

Pencil beam scanning (PBS) proton therapy provides highly conformal dose distributions that are increasingly leveraged for postmastectomy radiation therapy (PMRT) to reduce cardiopulmonary exposure. However, implant-based reconstruction in…

Cone-beam computed tomography (CBCT) offers advantages over conventional fan-beam CT in that it requires a shorter time and less exposure to obtain images. CBCT has found a wide variety of applications in patient positioning for…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 S. Kida , S. Kaji , K. Nawa , T. Imae , T. Nakamoto , S. Ozaki , T. Ohta , Y. Nozawa , K. Nakagawa

Many lung diseases require detailed visualisation for accurate diagnosis and treatment. High-resolution computed tomography (CT) is the gold-standard technique for non-invasive lung disease detection, but it presents a risk to the patient…

Objective: Accurate estimation of SAR is critical to safeguarding vulnerable patients who require an MRI procedure. The increased static field strength and RF duty cycle capabilities in modern MRI scanners mean that systems can easily…

Medical Physics · Physics 2020-09-11 J. Blackwell , G. Oluniran , B. Tuohy , M. Destrade , M. J. Kraśny , N. Colgan

Purpose: Cone-beam CT (CBCT) projection images provide anatomical data in real-time over several respiratory cycles, forming a comprehensive picture of tumor movement. We developed and validated a method which uses these projections to…

Medical Physics · Physics 2015-01-15 Bernard L. Jones , David Westerly , Moyed Miften

We test the feasibility of calculating proton stopping power (SP) from a set of virtual monochromatic (VM) CT images, created with Monte Carlo-generated CT scans, using a dual-energy CT-to-SP procedure. The Monte Carlo CT simulations, with…

Medical Physics · Physics 2022-06-23 Adam Zieser , Ugur Akgun , Yasar Onel

Proton computed tomography (pCT) is a novel imaging modality developed for patients receiving proton radiation therapy. The purpose of this work was to investigate hull-detection algorithms used for preconditioning of the large and sparse…

Computer Vision and Pattern Recognition · Computer Science 2014-02-10 Blake Schultze , Micah Witt , Yair Censor , Reinhard Schulte , Keith Evan Schubert

Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The visibility of the tumor in kV images is limited since the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yuzhen Ding , Hongying Feng , Yunze Yang , Jason Holmes , Zhengliang Liu , David Liu , William W. Wong , Nathan Y. Yu , Terence T. Sio , Steven E. Schild , Baoxin Li , Wei Liu

While compressed sensing (CS) based reconstructions have been developed for low-dose CBCT, a clear understanding on the relationship between the image quality and imaging dose at low dose levels is needed. In this paper, we qualitatively…

Medical Physics · Physics 2015-06-03 Hao Yan , Laura Cervino , Xun Jia , Steve B. Jiang

Objective: Machine learning (ML) based radiation treatment (RT) planning addresses the iterative and time-consuming nature of conventional inverse planning. Given the rising importance of Magnetic resonance (MR) only treatment planning…

Medical Physics · Physics 2022-06-13 Aly Khalifa , Jeff Winter , Inmaculada Navarro , Chris McIntosh , Thomas G. Purdie
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