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The analysis of dynamic organelles remains a formidable challenge, though key to understanding biological processes. We introduce Nellie, an automated and unbiased user-friendly pipeline for segmentation, tracking, and feature extraction of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Austin E. Y. T. Lefebvre , Gabriel Sturm , Ting-Yu Lin , Emily Stoops , Magdalena Preciado Lopez , Benjamin Kaufmann-Malaga , Kayley Hake

High-throughput image analysis in the biomedical domain has gained significant attention in recent years, driving advancements in drug discovery, disease prediction, and personalized medicine. Organoids, specifically, are an active area of…

Organoids are self-organized 3D cell clusters that closely mimic the architecture and function of in vivo tissues and organs. Quantification of organoid morphology helps in studying organ development, drug discovery, and toxicity…

Image and Video Processing · Electrical Eng. & Systems 2024-04-09 Xiaodan Xing , Chunling Tang , Yunzhe Guo , Nicholas Kurniawan , Guang Yang

This paper describes MAIA, a Multimodal Automated Interpretability Agent. MAIA is a system that uses neural models to automate neural model understanding tasks like feature interpretation and failure mode discovery. It equips a pre-trained…

Artificial Intelligence · Computer Science 2025-02-13 Tamar Rott Shaham , Sarah Schwettmann , Franklin Wang , Achyuta Rajaram , Evan Hernandez , Jacob Andreas , Antonio Torralba

Scientific discovery increasingly depends on high-throughput characterization, yet automation is hindered by proprietary GUIs and the limited generalizability of existing API-based systems. We present Owl-AuraID, a software-hardware…

AtomAI is an open-source software package bridging instrument-specific Python libraries, deep learning, and simulation tools into a single ecosystem. AtomAI allows direct applications of the deep convolutional neural networks for atomic and…

Data Analysis, Statistics and Probability · Physics 2022-12-29 Maxim Ziatdinov , Ayana Ghosh , Tommy Wong , Sergei V. Kalinin

The lack of annotated datasets is a major bottleneck for training new task-specific supervised machine learning models, considering that manual annotation is extremely expensive and time-consuming. To address this problem, we present MONAI…

Artificial Intelligence (AI) has become commonplace to solve routine everyday tasks. Because of the exponential growth in medical imaging data volume and complexity, the workload on radiologists is steadily increasing. We project that the…

Knee osteoarthritis (KOA) diagnosis from radiographs remains challenging due to the subtle morphological details that standard deep learning models struggle to capture effectively. We propose a novel multimodal framework that combines…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Marouane Tliba , Mohamed Amine Kerkouri , Yassine Nasser , Nour Aburaed , Aladine Chetouani , Ulas Bagci , Rachid Jennane

The advancement of artificial intelligence (AI) for organ segmentation and tumor detection is propelled by the growing availability of computed tomography (CT) datasets with detailed, per-voxel annotations. However, these AI models often…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Jie Liu , Yixiao Zhang , Kang Wang , Mehmet Can Yavuz , Xiaoxi Chen , Yixuan Yuan , Haoliang Li , Yang Yang , Alan Yuille , Yucheng Tang , Zongwei Zhou

Optoacoustic (OA) imaging is based on excitation of biological tissues with nanosecond-duration laser pulses followed by subsequent detection of ultrasound waves generated via light-absorption-mediated thermoelastic expansion. OA imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Firat Ozdemir , Berkan Lafci , Xosé Luís Deán-Ben , Daniel Razansky , Fernando Perez-Cruz

Interpretability studies often involve tracing the flow of information through machine learning models to identify specific model components that perform relevant computations for tasks of interest. Prior work quantifies the importance of a…

Machine Learning · Computer Science 2024-09-17 Maximilian Li , Lucas Janson

The integration of Artificial Intelligence (AI) into clinical workflows requires robust collaborative platforms that are able to bridge the gap between technical innovation and practical healthcare applications. This paper introduces MAIA…

Artificial Intelligence · Computer Science 2025-07-29 Simone Bendazzoli , Sanna Persson , Mehdi Astaraki , Sebastian Pettersson , Vitali Grozman , Rodrigo Moreno

Organoids are complex, three dimensional, self-organizing cell cultures which manifest organ-like features and represent a powerful platform for studying human disease and developing treatment options. Organoid development is characterized…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Chase Cartwright , Gongbo Guo , Sai Teja Pusuluri , Christopher N. Mayhew , Mark Hester , Horacio E. Castillo

The rapid expansion of scientific data has widened the gap between analytical capability and research intent. Existing AI-based analysis tools, ranging from AutoML frameworks to agentic research assistants, either favor automation over…

Artificial Intelligence · Computer Science 2025-10-14 Chuke Chen , Biao Luo , Nan Li , Boxiang Wang , Hang Yang , Jing Guo , Ming Xu

Recent advances in brain organoid technology are exciting new ways, which have the potential to change the way how doctors and researchers understand and treat cerebral diseases. Despite the remarkable use of brain organoids derived from…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Jingli Shi

Osteoporosis silently erodes skeletal integrity worldwide; however, early detection through imaging can prevent most fragility fractures. Artificial intelligence (AI) methods now mine routine Dual-energy X-ray Absorptiometry (DXA), X-ray,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-02 Abdul Rahman , Bumshik Lee

How can we develop visual analytics (VA) tools that can be easily adopted? Visualization researchers have developed a large number of web-based VA tools to help data scientists in a wide range of tasks. However, adopting these standalone…

Human-Computer Interaction · Computer Science 2023-05-16 Zijie J. Wang , David Munechika , Seongmin Lee , Duen Horng Chau

Background: There are many challenges and opportunities in the clinical deployment of AI tools in radiology. The current study describes a radiology software platform called NeoMedSys that can enable efficient deployment and refinements of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Qinghui Liu , Jon E. Nesvold , Hanna Raaum , Elakkyen Murugesu , Martin Røvang , Bradley J Maclntosh , Atle Bjørnerud , Karoline Skogen

MOTIVATION: Microarray technology makes it possible to measure thousands of variables and to compare their values under hundreds of conditions. Once microarray data are quantified, normalized and classified, the analysis phase is…

Quantitative Methods · Quantitative Biology 2007-09-11 Claude Pasquier , Fabrice Girardot , Karim Jevardat De Fombelle , Richard Christen
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