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We present a novel mathematical model that simulates myocardial blood perfusion by embedding multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, reduced valve…

Computational Engineering, Finance, and Science · Computer Science 2023-03-27 Alberto Zingaro , Christian Vergara , Luca Dede' , Francesco Regazzoni , Alfio Quarteroni

A network-based approach is presented to investigate the cerebrovascular flow patterns during atrial fibrillation (AF) with respect to normal sinus rhythm (NSR). AF, the most common cardiac arrhythmia with faster and irregular beating, has…

Data Analysis, Statistics and Probability · Physics 2017-09-27 Stefania Scarsoglio , Fabio Cazzato , Luca Ridolfi

The four essential chambers of one's heart that lie in the thoracic cavity are crucial for one's survival, yet ironically prove to be the most vulnerable. Cardiovascular disease (CVD) also commonly referred to as heart disease has steadily…

Machine Learning · Computer Science 2021-11-17 Aaditya Surya

This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…

Computational Physics · Physics 2025-05-30 Olaf Dössel , Axel Loewe

Computational models are continuously integrated in the clinical space, where they support clinicians in disease diagnosis, prognosis, and prevention strategies. While assisting in clinical space, these computational models frequently use…

Medical Physics · Physics 2026-04-30 Muhammad Usman , Peter N. Castillo , Akil Narayan , Lucas H. Timmins

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

Fluid Dynamics · Physics 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

The complexity of the cardiovascular system needs to be accurately reproduced in order to promptly acknowledge health conditions; to this aim, advanced multifidelity and multiphysics numerical models are crucial. On one side, Full Order…

Computational models in cardiac electrophysiology are notorious for long runtimes, restricting the numbers of nodes and mesh elements in the numerical discretisations used for their solution. This makes it particularly challenging to…

Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Patryk Rygiel , Julian Suk , Kak Khee Yeung , Christoph Brune , Jelmer M. Wolterink

Vascular calcification is implicated as an important factor in major adverse cardiovascular events (MACE), including heart attack and stroke. A controversy remains over how to integrate the diverse forms of vascular calcification into…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Mehdi Ramezanpour , Anne M. Robertson , Yasutaka Tobe , Xiaowei Jia , Juan R. Cebral

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Ehab Abdelmaguid , Jolene Huang , Sanjay Kenchareddy , Disha Singla , Laura Wilke , Mai H. Nguyen , Ilkay Altintas

Despite the significant role of turbomachinery in fluid-based energy transfer, precise simulation of rotating solid objects with complex geometry is a challenging task. In the present study, the volume penalization method (VPM) is combined…

Fluid Dynamics · Physics 2026-01-16 Ming Liu , Yosuke Hasegawa

The introduction of computational models in cardiovascular sciences has been progressively bringing new and unique tools for the investigation of the physiopathology. Together with the dramatic improvement of imaging and measuring devices…

In today's world, a massive amount of data is available in almost every sector. This data has become an asset as we can use this enormous amount of data to find information. Mainly health care industry contains many data consisting of…

Machine Learning · Computer Science 2022-03-10 Hafsa Binte Kibria , Abdul Matin

This study presents a novel methodology for stratifying post-myocardial infarction patients at risk of ventricular arrhythmias using patient-specific 3D cardiac models derived from late gadolinium enhancement cardiovascular magnetic…

Computational Engineering, Finance, and Science · Computer Science 2024-09-11 Dolors Serra , Pau Romero , Paula Franco , Ignacio Bernat , Miguel Lozano , Ignacio Garcia-Fernandez , David Soto , Antonio Berruezo , Oscar Camara , Rafael Sebastian

Numerical model of the peripheral circulation and dynamical model of the large vessels and the heart are discussed in this paper. They combined together into the global model of blood circulation. Some results of numerical simulations…

Biological Physics · Physics 2007-12-31 S. S. Simakov , A. S. Kholodov , A. V. Evdokimov , Y. A. Kholodov

Atrial fibrillation (AF) is the most common abnormal heart rhythm and the single biggest cause of stroke. Ablation, destroying regions of the atria, is applied largely empirically and can be curative but with a disappointing clinical…

Medical Physics · Physics 2015-06-19 Kim Christensen , Kishan A. Manani , Nicholas S. Peters

Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically…

Medical Physics · Physics 2025-11-06 Yaqi Li , Justin D. Weigand , Charles Puelz , Mette S. Olufsen , Alyssa Taylor-LaPole

Atrial fibrillation (AF) is the most common cardiac arrhythmia in human beings, and is associated with significant morbidity and mortality. The current standard of care includes interventional catheter ablation in selected patients, but the…