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Sleep foundation models have recently demonstrated strong performance on in-domain polysomnography tasks, including sleep staging, apnea detection, and disease risk prediction. In this work, we investigate whether sleep biosignals can serve…

In the process of patient diagnosis, non-invasive measurements are widely used due to their low risks and quick results. Electrocardiogram (ECG), as a non-invasive method to collect heart activities, is used to diagnose cardiac conditions.…

Machine Learning · Computer Science 2025-12-11 Yuhao Xu , Jiaying Lu , Sirui Ding , Defu Cao , Xiao Hu , Carl Yang

Electrocardiogram (ECG) foundation models pretrained on typical diagnostic 10-second ECG segments, have demonstrated strong transferability across a range of clinical applications. However, many real-world applications produce recordings…

Electroencephalography (EEG) signals reflect activities on certain brain areas. Effective classification of time-varying EEG signals is still challenging. First, EEG signal processing and feature engineering are time-consuming and highly…

Human-Computer Interaction · Computer Science 2019-08-27 Xiang Zhang , Lina Yao , Xianzhi Wang , Wenjie Zhang , Shuai Zhang , Yunhao Liu

EEG foundation models are typically pretrained on narrow-source clinical archives and evaluated on benchmarks from the same ecosystem, leaving unclear whether representations encode neural physiology or recording-distribution artifacts. We…

Brain computer interface (BCI) research, as well as increasing portions of the field of neuroscience, have found success deploying large-scale artificial intelligence (AI) pre-training methods in conjunction with vast public repositories of…

Neurons and Cognition · Quantitative Biology 2025-06-03 Mattson Ogg , Rahul Hingorani , Diego Luna , Griffin W. Milsap , William G. Coon , Clara A. Scholl

Electroencephalography (EEG) has wide-ranging applications, from clinical diagnosis to brain-computer interfaces (BCIs). With the increasing volume and variety of EEG data, there has been growing interest in establishing foundation models…

Machine Learning · Computer Science 2025-10-21 Zitao Fang , Chenxuan Li , Hongting Zhou , Shuyang Yu , Guodong Du , Ashwaq Qasem , Yang Lu , Jing Li , Junsong Zhang , Sim Kuan Goh

Nowadays, machine and deep learning techniques are widely used in different areas, ranging from economics to biology. In general, these techniques can be used in two ways: trying to adapt well-known models and architectures to the available…

Machine Learning · Computer Science 2022-03-21 Danilo Avola , Marco Cascio , Luigi Cinque , Alessio Fagioli , Gian Luca Foresti , Marco Raoul Marini , Daniele Pannone

Electroencephalography (EEG) foundation models hold significant promise for universal Brain-Computer Interfaces (BCIs). However, existing approaches often rely on end-to-end fine-tuning and exhibit limited efficacy under frozen-probing…

Machine Learning · Computer Science 2026-03-20 Jiquan Wang , Sha Zhao , Yangxuan Zhou , Yiming Kang , Shijian Li , Gang Pan

Foundation models have transformed AI by reducing reliance on task-specific data through large-scale pretraining. While successful in language and vision, their adoption in EEG has lagged due to the heterogeneity of public datasets, which…

Multimodal language modeling has enabled breakthroughs for representation learning, yet remains unexplored in the realm of functional brain data for clinical phenotyping. This paper pioneers EEG-language models (ELMs) trained on clinical…

Signal Processing · Electrical Eng. & Systems 2025-08-12 Sam Gijsen , Kerstin Ritter

Electrocardiogram~(ECG), a key bioelectrical time-series signal, is crucial for assessing cardiac health and diagnosing various diseases. Given its time-series format, ECG data is often incorporated into pre-training datasets for…

Signal Processing · Electrical Eng. & Systems 2026-02-26 Zhijiang Tang , Jiaxin Qi , Yuhua Zheng , Jianqiang Huang

Electroencephalography (EEG) is a non-invasive technique to measure and record brain electrical activity, widely used in various BCI and healthcare applications. Early EEG decoding methods rely on supervised learning, limited by specific…

Signal Processing · Electrical Eng. & Systems 2025-11-07 Jiquan Wang , Sha Zhao , Zhiling Luo , Yangxuan Zhou , Haiteng Jiang , Shijian Li , Tao Li , Gang Pan

Foundation models (FMs) promise to extract unified representations that generalize across downstream tasks. They have emerged across fields, including electroencephalography (EEG), but it is less clear how effective they are in this…

We introduce a unified benchmarking framework focused on evaluating EEG-based foundation models in clinical applications. The benchmark spans 11 well-defined diagnostic tasks across 14 publicly available EEG datasets, including epilepsy,…

Machine Learning · Computer Science 2025-12-11 Ard Kastrati , Josua Bürki , Jonas Lauer , Cheng Xuan , Raffaele Iaquinto , Roger Wattenhofer

Electroencephalography foundation models (EEG-FMs) have advanced brain signal analysis, but the lack of standardized evaluation benchmarks impedes model comparison and scientific progress. Current evaluations rely on inconsistent protocols…

Signal Processing · Electrical Eng. & Systems 2026-02-16 Wei Xiong , Jiangtong Li , Jie Li , Kun Zhu , Changjun Jiang

Electroencephalography (EEG) is commonly used by physicians for the diagnosis of numerous neurological disorders. Due to the large volume of EEGs requiring interpretation and the specific expertise involved, artificial intelligence-based…

Foundation models pre-trained through masked reconstruction on large-scale EEG data have emerged as a promising paradigm for learning generalizable neural representations across diverse brain-computer interface applications. However, a…

Artificial Intelligence · Computer Science 2026-05-19 Yang Shao , Peiliang Gong , Qun Dai , Daoqiang Zhang

Large-scale foundation models for EEG signals offer a promising path to generalizable brain-computer interface (BCI) applications, but they often suffer from misalignment between pretraining objectives and downstream tasks, as well as…

Machine Learning · Computer Science 2025-10-03 Suli Wang , Yangshen Deng , Zhenghua Bao , Xinyu Zhan , Yiqun Duan

EEG foundation models, pre-trained on large-scale unlabelled EEG data, have emerged as a promising direction towards learning generalizable EEG representations. Despite showing positive results in data-rich regimes, they often fail to…