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Related papers: AI Agents in Drug Discovery

200 papers

The era of intelligent agents is upon us, driven by revolutionary advancements in large language models. Large Language Model (LLM) agents, with goal-driven behaviors and dynamic adaptation capabilities, potentially represent a critical…

Generative artificial intelligence (AI) agents are increasingly embedded in collaborative learning environments, yet their impact on the processes of argumentative knowledge construction remains insufficiently understood. Emerging…

Human-Computer Interaction · Computer Science 2025-12-11 Lixiang Yan , Yueqiao Jin , Linxuan Zhao , Roberto Martinez-Maldonado , Xinyu Li , Xiu Guan , Wenxin Guo , Xibin Han , Dragan Gašević

The endowment of AI with reasoning capabilities and some degree of agency is widely viewed as a path toward more capable and generalizable systems. Our position is that the current development of agentic AI requires a more holistic,…

Advanced scientific user facilities, such as next generation X-ray light sources and self-driving laboratories, are revolutionizing scientific discovery by automating routine tasks and enabling rapid experimentation and characterizations.…

Instrumentation and Detectors · Physics 2025-09-03 Aikaterini Vriza , Michael H. Prince , Tao Zhou , Henry Chan , Mathew J. Cherukara

Agentic Al systems are increasingly deployed as personal assistants and are likely to become a common object of digital investigations. However, little is known about how their internal state and actions can be reconstructed during forensic…

Cryptography and Security · Computer Science 2026-04-08 Jan Gruber , Jan-Niclas Hilgert

Autonomous agents powered by Large Language Models are transforming AI, creating an imperative for the visualization field to embrace agentic frameworks. However, our field's focus on a human in the sensemaking loop raises critical…

Human-Computer Interaction · Computer Science 2025-09-17 Vaishali Dhanoa , Anton Wolter , Gabriela Molina León , Hans-Jörg Schulz , Niklas Elmqvist

Next-generation instruments for ground-based gamma-ray astronomy are marked by a substantial increase in complexity, featuring dozens of telescopes. This leap in scale introduces significant challenges in managing system operations and…

Instrumentation and Methods for Astrophysics · Physics 2025-03-04 D. Kostunin , V. Sotnikov , S. Golovachev , A. Strube

In recent years, agentic artificial intelligence (AI) systems are becoming increasingly widespread. These systems allow agents to use various tools, such as web browsers, compilers, and more. However, despite their popularity, agentic AI…

The rapid advancement of intelligent agents and Large Language Models (LLMs) is reshaping the pervasive computing field. Their ability to perceive, reason, and act through natural language understanding enables autonomous problem-solving in…

Artificial Intelligence · Computer Science 2025-12-19 Gianni Molinari , Fabio Ciravegna

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

Artificial Intelligence · Computer Science 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Large language models (LLMs) have emerged as powerful tools in chemistry, significantly impacting molecule design, property prediction, and synthesis optimization. This review highlights LLM capabilities in these domains and their potential…

Machine Learning · Computer Science 2024-11-18 Mayk Caldas Ramos , Christopher J. Collison , Andrew D. White

In computational biophysics, where molecular data is expanding rapidly and system complexity is increasing exponentially, large language models (LLMs) and agent-based systems are fundamentally reshaping the field. This perspective article…

This paper presents an integrative review and experimental validation of artificial intelligence (AI) agents applied to music analysis and education. We synthesize the historical evolution from rule-based models to contemporary approaches…

Artificial Intelligence · Computer Science 2025-11-19 Antonio Manuel Martínez-Heredia , Dolores Godrid Rodríguez , Andrés Ortiz García

Agents and agent systems are becoming more and more important in the development of a variety of fields such as ubiquitous computing, ambient intelligence, autonomous computing, intelligent systems and intelligent robotics. The need for…

Artificial Intelligence · Computer Science 2009-02-23 Mark Burgin , Gordana Dodig-Crnkovic

The substantial data volumes encountered in modern particle physics and other domains of fundamental physics research allow (and require) the use of increasingly complex data analysis tools and workflows. While the use of machine learning…

High Energy Physics - Phenomenology · Physics 2026-02-18 Sascha Diefenbacher , Anna Hallin , Gregor Kasieczka , Michael Krämer , Anne Lauscher , Tim Lukas

Drug discovery is a long, expensive, and complex process, relying heavily on human medicinal chemists, who can spend years searching the vast space of potential therapies. Recent advances in artificial intelligence for chemistry have sought…

Computation and Language · Computer Science 2025-10-14 Reza Averly , Frazier N. Baker , Ian A. Watson , Xia Ning

AI agents that take actions in their environment autonomously over extended time horizons require robust governance interventions to curb their potentially consequential risks. Prior proposals for governing AI agents primarily target…

Computers and Society · Computer Science 2025-12-02 K. J. Kevin Feng , Tae Soo Kim , Rock Yuren Pang , Faria Huq , Tal August , Amy X. Zhang

Agentic AI systems powered by large language models (LLMs) and endowed with planning, tool use, memory, and autonomy, are emerging as powerful, flexible platforms for automation. Their ability to autonomously execute tasks across web,…

Artificial Intelligence · Computer Science 2026-04-07 Anshuman Chhabra , Shrestha Datta , Shahriar Kabir Nahin , Prasant Mohapatra

Agentic AI systems -- Large Language Models (LLMs) augmented with planning, tool use, memory, and long-horizon interactions -- can execute complex tasks autonomously, but their multi-step trajectories introduce new failure modes that…

Artificial Intelligence · Computer Science 2026-05-26 Jinhu Qi , Muzhi Li , Jiahong Liu , Yuqin Shu , Dianzhi Yu , Shicheng Ma , Wenqian Cui , Yiyang Zhao , Yiyi Chen , Ruoxi Jiang , Irwin King , Zenglin Xu
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