English
Related papers

Related papers: AI Agents in Drug Discovery

200 papers

Computing has long served as a cornerstone of scientific discovery. Recently, a paradigm shift has emerged with the rise of large language models (LLMs), introducing autonomous systems, referred to as agents, that accelerate discovery…

The delivery of traditional substance education has remained problematic due to challenges in scalability, personalization, and the currency of information in a rapidly evolving substance use landscape. While artificial intelligence (AI)…

Computation and Language · Computer Science 2026-05-04 Kosar Haghani , Zahra Kolagar , Mohammed Atiquzzaman

Autonomous multi-agent AI systems are poised to transform various industries, particularly software development and knowledge work. Understanding current perceptions among professionals is crucial for anticipating adoption challenges,…

Computers and Society · Computer Science 2025-06-04 Nikola Balic

As the volume and complexity of nonclinical toxicology studies continue to increase, toxicologic pathology reporting faces persistent challenges, including fragmented sources of data (e.g., histopathology images, clinical pathology and…

Artificial intelligence (AI) has sparked immense interest in drug discovery, but most current approaches only digitize existing high-throughput experiments. They remain constrained by conventional pipelines. As a result, they do not address…

Computers and Society · Computer Science 2025-07-29 You Wu , Philip E. Bourne , Lei Xie

The study of cooperation within social dilemmas has long been a fundamental topic across various disciplines, including computer science and social science. Recent advancements in Artificial Intelligence (AI) have significantly reshaped…

Artificial Intelligence · Computer Science 2024-07-31 Chunjiang Mu , Hao Guo , Yang Chen , Chen Shen , Shuyue Hu , Zhen Wang

In this paper, we describe and benchmark a competitor-discovery component used within an agentic AI system for fast drug asset due diligence. A competitor-discovery AI agent, given an indication, retrieves all drugs comprising the…

Building agents, systems that perceive and act upon their environment with a degree of autonomy, has long been a focus of AI research. This pursuit has recently become vastly more practical with the emergence of large language models (LLMs)…

AI agents that leverage Large Language Models (LLMs) are increasingly becoming core building blocks of modern software systems. A wide range of frameworks is now available to support the specification of such applications. These frameworks…

Artificial Intelligence · Computer Science 2025-11-04 Fabiana Fournier , Lior Limonad , Yuval David

Large Language Models (LLMs) have emerged as powerful tools for accelerating scientific discovery, yet their static knowledge and hallucination issues hinder autonomous research applications. Recent advances integrate LLMs into agentic…

Artificial Intelligence · Computer Science 2025-12-23 Zeyu Xia , Jinzhe Ma , Congjie Zheng , Shufei Zhang , Yuqiang Li , Hang Su , P. Hu , Changshui Zhang , Xingao Gong , Wanli Ouyang , Lei Bai , Dongzhan Zhou , Mao Su

AI agents that combine large language models with non-AI system components are rapidly emerging in real-world applications, offering unprecedented automation and flexibility. However, this unprecedented flexibility introduces complex…

Cryptography and Security · Computer Science 2026-03-13 Juhee Kim , Xiaoyuan Liu , Zhun Wang , Shi Qiu , Bo Li , Wenbo Guo , Dawn Song

Large Language Model (LLM) agents, acting on their users' behalf to manipulate and analyze data, are likely to become the dominant workload for data systems in the future. When working with data, agents employ a high-throughput process of…

Artificial intelligence (AI) in the form of deep learning bears promise for drug discovery and chemical biology, $\textit{e.g.}$, to predict protein structure and molecular bioactivity, plan organic synthesis, and design molecules…

Biomolecules · Quantitative Biology 2022-12-29 Rıza Özçelik , Derek van Tilborg , José Jiménez-Luna , Francesca Grisoni

Traditional drug discovery is a long, expensive, and complex process. Advances in Artificial Intelligence (AI) and Machine Learning (ML) are beginning to change this narrative. Here, we provide a comprehensive overview of different AI and…

Artificial Intelligence · Computer Science 2024-11-12 Khartik Uppalapati , Eeshan Dandamudi , S. Nick Ice , Gaurav Chandra , Kirsten Bischof , Christian L. Lorson , Kamal Singh

The development of AI agents based on large, open-domain language models (LLMs) has paved the way for the development of general-purpose AI assistants that can support human in tasks such as writing, coding, graphic design, and scientific…

Artificial Intelligence · Computer Science 2025-06-03 Mustafa Mert Çelikok , Saptarashmi Bandyopadhyay , Robert Loftin

Trust in AI agents has been extensively studied in the literature, resulting in significant advancements in our understanding of this field. However, the rapid advancements in Large Language Models (LLMs) and the emergence of LLM-based AI…

Artificial Intelligence · Computer Science 2023-08-11 Sivan Schwartz , Avi Yaeli , Segev Shlomov

AI agents have been boosted by large language models. AI agents can function as intelligent assistants and complete tasks on behalf of their users with access to tools and the ability to execute commands in their environments. Through…

Cryptography and Security · Computer Science 2024-12-19 Yifeng He , Ethan Wang , Yuyang Rong , Zifei Cheng , Hao Chen

Drug discovery remains a formidable challenge: more than 90 percent of candidate molecules fail in clinical evaluation, and development costs often exceed one billion dollars per approved therapy. Disparate data streams, from genomics and…

Artificial Intelligence · Computer Science 2025-04-28 Kevin Song , Andrew Trotter , Jake Y. Chen

With recent advancements in multi-agent generative AI (Gen AI), technology organizations like Microsoft are adopting these complex tools, redefining AI agents as active collaborators in complex workflows rather than as passive tools. In…

Human-Computer Interaction · Computer Science 2025-10-09 Suchismita Naik , Austin L. Toombs , Amanda Snellinger , Scott Saponas , Amanda K. Hall

Large language models and autonomous AI agents have evolved rapidly, resulting in a diverse array of evaluation benchmarks, frameworks, and collaboration protocols. Driven by the growing need for standardized evaluation and integration, we…

Artificial Intelligence · Computer Science 2026-03-10 Mohamed Amine Ferrag , Norbert Tihanyi , Merouane Debbah