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Motivated by the observations of intracellular phase separations and the wetting of cell membranes by protein droplets, we study the nonequilibrium surface wetting by Monte Carlo simulations of a lattice gas model involving particle…

Biological Physics · Physics 2022-06-23 Kyosuke Adachi , Kyogo Kawaguchi

Bubble nucleation in liquid confined in nanochannel is studied using molecular dynamics simulations and compared against nucleation in the liquid over smooth (i.e. without confinement). Nucleation is achieved by heating part of a surface to…

Fluid Dynamics · Physics 2022-01-24 Manish Gupta , Shalabh C. Maroo

Hypotheses: Additives are commonly used to tune macromolecular conformational transitions. Among additives, trehalose is an excellent bioprotectant and among responsive polymers, PNIPAM is the most studied material. Nevertheless, their…

The understanding of dynamics and functioning of biological membranes and in particular of membrane embedded proteins is one of the most fundamental problems and challenges in modern biology and biophysics. In particular the impact of…

Biological Physics · Physics 2009-12-27 Maikel C. Rheinstadter

Phase separation in biomolecular mixtures can result from multiple physical interactions, which may act either complementarily or antagonistically. In the case of protein-nucleic acid mixtures, charge plays a key role but can have…

Soft Condensed Matter · Physics 2026-05-13 Gabrielle R. Abraham , Tianhao Li , Anna Nguyen , William M. Jacobs , Omar A. Saleh

We study capillary condensation in a bath consisting of active Brownian particles (ABPs) and the forces acting on the capillary close to the motility-induced phase separation (MIPS). The capillary is modelled as two parallel rods of high…

Soft Condensed Matter · Physics 2019-08-29 Milos Knezevic , Holger Stark

Artificial soft matter systems have appeared as important tools to harness mechanical motion for microscale manipulation. Typically, this motion is driven either by the external fields or by mutual interaction between the colloids. In the…

Soft Condensed Matter · Physics 2024-11-20 Rahul Chand , Ashutosh Shukla , Sneha Boby , G V Pavan Kumar

The properties of an active fluid, for example, a bacterial bath or a collection of microtubules and molecular motors, can be accessed through the dynamics of passive particle probes. Here, in the perspective of analyzing experimental…

Soft Condensed Matter · Physics 2024-03-19 Cristian Villalobos , María Luisa Cordero , Eric Clément , Rodrigo Soto

In this work we present the dielectric behavior of water with a novel flexible model that improved all three sites water models Different concentrations of the ionic liquid 1- butyl-3-methylimidazolium [bmim]…

The elucidation of entropic contribution to enzyme catalysis has been debated over decades. The recent experimentally measured activation enthalpy and entropy, for chorismate rearrangement reaction in PchB brings up a hotly debated issue…

Biomolecules · Quantitative Biology 2017-11-07 Liangxu Xie , Zhe-Ning Chen , Mingjun Yang

Liquid-liquid phase separation has recently emerged as an important topic in the context of cellular organization. Within this context, there are multiple poorly understood features; for instance hints of critical behavior in the plasma…

Statistical Mechanics · Physics 2024-06-25 Felix Herrmann , Burkhard Dünweg , Martin Girard

The solvent quality determines the collapsed or the expanded state of a polymer. For example, a polymer dissolved in a poor solvent collapses, whereas in a good solvent it opens up. While this standard understanding is generally valid,…

Soft Condensed Matter · Physics 2020-07-01 Yani Zhao , Manjesh K. Singh , Kurt Kremer , Robinson Cortes-Huerto , Debashish Mukherji

We present a joint experimental and computational study of the effect of bacterial motion on micron-scale colloids contained in a two-dimensional suspension of Bacillus subtilis. With respect to previous work using E. coli, here we…

Soft Condensed Matter · Physics 2011-09-20 Chantal Valeriani , Martin Li , John Novosel , Jochen Arlt , Davide Marenduzzo

Twenty years ago Poole et al. (Nature 360, 324, 1992) suggested that the anomalous properties of supercooled water may be caused by a critical point that terminates a line of liquid-liquid separation of lower-density and higher-density…

Chemical Physics · Physics 2017-08-14 V. Holten , M. A. Anisimov

We construct a Hamiltonian for a single domain protein where the contact enthalpy and the chain entropy decrease linearly with the number of native contacts. The hydration effect upon protein unfolding is included by modeling water as ideal…

Condensed Matter · Physics 2009-11-07 Audun Bakk , Johan S. Hoye , Alex Hansen

Biomolecules, such as proteins and RNAs, can phase separate in the cytoplasm of cells to form biomolecular condensates. Such condensates are liquid-like droplets that can wet biological surfaces such as membranes. Many molecules that…

Soft Condensed Matter · Physics 2024-09-04 Xueping Zhao , Susanne Liese , Alf Honigmann , Frank Jülicher , Christoph A. Weber

Many different processes take place to facilitate lubrication of the joints functioning in human locomotion system. The main purpose of this is to avoid destroying the articular cartilage. Viscoelastic properties of the joints system are…

Biological Physics · Physics 2019-11-22 Natalia Kruszewska , Piotr Bełdowski , Krzysztof Domino , Kanika D Lambert

Water dissociation is a rate limiting step in many industrially important chemical reactions. In this investigation, climbing image nudged elastic band (CINEB) method, within the framework of density functional theory, is used to report the…

Materials Science · Physics 2016-02-04 Vaibhav Kaware , Kavita Joshi

We numerically study the energy transfer in a multi-component $2d$ film, made of an active polar gel and a passive isotropic fluid in presence of surfactant favoring emulsification. We show that by confining the active behavior into the…

Soft Condensed Matter · Physics 2020-08-18 Livio Nicola Carenza , Luca Biferale , Giuseppe Gonnella

We study the kinetics of two-temperature induced phase separation (2-TIPS) in dilute binary mixtures of active ("hot") and passive ("cold") particles using molecular dynamics simulations and a coarse-grained hydrodynamic model. Following a…

Soft Condensed Matter · Physics 2025-12-23 Nayana Venkatareddy , Partha Sarathi Mondal , Shradha Mishra , Prabal K. Maiti