Related papers: Enzyme Active Bath Affects Protein Condensation
Active Brownian particles (ABPs) with pure repulsion is an ideal model to understand the effect of nonequilibrium on collective behaviors. It has long been established that activity can create effective attractions leading to…
1. Role of inter-domain water clusters in large-scale dynamics of proteins; 2. Description of large-scale dynamics of proteins based on generalized Stokes-Einstein and Eyring-Polany equation; 3. Dynamic model of protein-ligand complexes…
Dissipation is introduced to a strongly interacting ultracold bosonic gas in the Mott-insulator regime of a 3D spin-dependent optical lattice. A weakly interacting superfluid comprised of atoms in a state that does not experience the…
Characterizing the properties of an extended system driven by active reservoirs is a question of increasing importance. Here we address this question in two steps. We start by investigating the dynamics of a probe particle connected to an…
Low-density lipoproteins (LDLs) serve as nutrient reservoirs in egg yolk for embryonic development and as promising drug carriers. Both roles critically depend on their mobility in densely crowded biological environments. Under these…
We investigate dense suspensions of swimming bacteria prepared in a nutrient-exchange chamber. Near the pellet concentration, nonthermal fluctuations showed notable agreement between self and collective behaviors, a phenomenon not…
Enzymes have been recently found to exhibit enhanced diffusion due to their catalytic activities. A recent experiment [C. Riedel et al., Nature 517, 227 (2015)] has found evidence that suggests this phenomenon might be controlled by the…
The interplay between phase separation and wetting of multicomponent mixtures is ubiquitous in nature and technology and recently gained significant attention across scientific disciplines, due to the discovery of biomolecular condensates.…
In order to inquire the microscopic origin of observed multiple time scales in solvation dynamics we carry out several computer experiments. We perform atomistic molecular dynamics simulations on three protein-water systems namely,…
We study theoretically the thermodynamics, over a broad temperature range (5 C to 125 C), related to hydrated water upon protein unfolding. The hydration effect is modeled as interacting dipoles in an external field, mimicking the influence…
We follow the dynamics of an ensemble of interacting self-propelled semi-flexible polymers in contact with a thermal bath. We characterize structure and dynamics of the passive system and as a function of the motor activity. We find that…
Microphase separation is common in active biological systems as exemplified by the separation of RNA and DNA-rich phases in the cell nucleus driven by the transcriptional activity of polymerase enzymes acting similarly to amphiphiles in a…
Motility-induced phase separation (MIPS) is a central collective phenomenon in active matter, theoretically established in the overdamped regime. We discover that the dynamical origin of MIPS is fundamentally altered by inertia, which…
The behavior of proteins near interfaces is relevant for biological and medical purposes. Previous results in bulk show that, when the protein concentration increases, the proteins unfold and, at higher concentrations, aggregate. Here, we…
The interactions of a protein, its phase behavior, and ultimately, its ability to function, are all influenced by the interactions between the protein and its hydration waters. Here we study proteins with a variety of sizes, shapes,…
Enzymes are essential to maintain organisms alive. Some of the reactions they catalyze are associated with a change in reagents chirality, hence their activity can be tracked by using optical means. However, illumination affects enzyme…
Effects of substrate temperature, substrate wettability and particles concentration are experimentally investigated for evaporation of a sessile water droplet containing colloidal particles. Time-varying droplet shapes and temperature of…
Protein nanoparticles have been proven to be highly effective stabilizers of water-in-water emulsions obtained from a number of different types of aqueous two-phase systems (ATPS). The stabilizing efficiency of such particles is attributed…
The evaporation of particle-laden droplets on engineered surfaces underpins a wide range of technologies, from printed electronics to biosensing. While the influence of substrate topography on passive particle deposition is well…
Active matter systems such as eukaryotic cells and bacteria continuously transform chemical energy to motion. Hence living systems exert active stresses on the complex environments in which they reside. One recurring aspect of this…