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The purpose of this study is to enable in-vivo three-dimensional (3-D) ultrasound localization microscopy (ULM) of posterior ocular microvasculature using a 256-channel system and a 1024-element matrix array, and to overcome limitations of…

There is currently no widely adopted standard for the optical characterisation of fluorescence microscopes. We used laser written fluorescence to generate two- and three-dimensional patterns to deliver a quick and quantitative measure of…

Aberration-corrected Scanning Transmission Electron Microscopy (STEM) has become an essential tool in understanding materials at the atomic scale. However, tuning the aberration corrector to produce a sub-{\AA}ngstr\"om probe is a complex…

The optical diffraction limit, formulated by Abbe 140 years ago, imposes a bound on imaging resolution in classical optics. Over the last twenty years, many theoretical schemes have been presented for overcoming the diffraction barrier in…

Quantum Physics · Physics 2013-07-12 O. Schwartz , J. M. Levitt , R. Tenne , S. Itzhakov , Z. Deutsch , D. Oron

Plenoptic cameras use arrays of micro-lenses to capture multiple views of the same scene in a single compound image. They enable refocusing on different planes and depth estimation. However, until now, all types of plenoptic computational…

Optics · Physics 2020-01-29 K. M. Sowa , M. P. Kujda , P. Korecki

We report the experimental super-resolution of pairs of point-like fluorescent sources using a modified image inversion interferometer microscope. The technique is inspired by recent developments in the application of quantum parameter…

A new method for solving small X-ray structures with up to couple of hundreds of atoms in the unit cell has been developed. The method works by locating atoms one-by-one via global minimization of a newly defined single-atom R1 factor in…

Data Analysis, Statistics and Probability · Physics 2024-03-21 Xiaodong Zhang

Fundamental understanding of biological pathways requires minimally invasive nanoscopic optical resolution imaging. Many approaches to high-resolution imaging rely on localization of single emitters, such as fluorescent molecule or quantum…

Quantum Physics · Physics 2022-04-05 Shuo Li , Wenchao Li , Vladislav V. Yakovlev , Allison Kealy , Andrew D. Greentree

The size- and fluorescence-based sorting of micro- and nano-scale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here we demonstrate…

Soft Condensed Matter · Physics 2015-02-16 Sukumar Rajauria , Christopher Axline , Claudia Gottstein , Andrew N. Cleland

In x-ray microscopy, traditional raster-scanning techniques are used to acquire a microscopic image in a series of step-scans. Alternatively, scanning the x-ray probe along a continuous path, called a fly-scan, reduces scan time and…

Image and Video Processing · Electrical Eng. & Systems 2025-09-23 Yu Lu , Thomas F. Lynn , Ming Du , Zichao Di , Sven Leyffer

This Point spread function (PSF) plays a crucial role in many computational imaging applications, such as shape from focus/defocus, depth estimation, and fluorescence microscopy. However, the mathematical model of the defocus process is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Renzhi He , Yan Zhuang , Boya Fu , Fei Liu

Microscopy enables direct observation of cellular morphology in 3D, with transmitted-light methods offering low-cost, minimally invasive imaging and fluorescence microscopy providing specificity and contrast. Virtual staining combines these…

Ghost imaging needs massive measurements to obtain an image with good visibility and the imaging speed is usually very low. In order to realize real-time high-resolution ghost imaging of a target which is located in a scenario with a large…

Image and Video Processing · Electrical Eng. & Systems 2019-05-22 Cheng Zhou , Tian Tian , Chao Gao , Wenli Gong , Lijun Song

Nanophotonics offers a promising range of applications spanning from the development of efficient solar cells to quantum communications and biosensing. However, the ability to efficiently couple fluorescent emitters with nanostructured…

We report both sub-diffraction-limited quantum metrology and quantum enhanced spatial resolution for the first time in a biological context. Nanoparticles are tracked with quantum correlated light as they diffuse through an extended region…

Interference of light fields plays an important role in various high-precision measurement schemes. It has been shown that super resolving phase measurements beyond the standard coherent state limit can be obtained either by using maximally…

Quantum Physics · Physics 2013-10-08 Emanuele Distante , Miroslav Jezek , Ulrik L. Andersen

Multi-photon microscopy is a powerful tool in biomolecular research. Less complex and more cost effective excitation light sources will make this technique accessible to a broader community. Especially semiconductor diode seeded fiber…

Molecular and atomic imaging required the development of electron and scanning probe microscopies to surpass the physical limits dictated by diffraction. Nano-infrared experiments and pico-cavity tip-enhanced Raman spectroscopy imaging…

High-precision optical phase stabilization in quantum networks is fundamentally constrained by the strict photon-flux and duty-cycle limits required to avoid disturbing fragile quantum states. This challenge becomes especially critical when…

Polarized light microscopy using path-entangled $N$-photon states (i.e., the N00N states) has been demonstrated to surpass the shot-noise limit at very low light illumination. However, the microscopy images suffer from divergence of phase…

Quantum Physics · Physics 2017-01-27 G. R. Jin , W. Yang , C. P. Sun
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