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Neural networks achieve state-of-the-art performance in many supervised learning tasks when the training data distribution matches the test data distribution. However, their performance drops significantly under domain (covariate) shift, a…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Kerem Cekmeceli , Meva Himmetoglu , Guney I. Tombak , Anna Susmelj , Ertunc Erdil , Ender Konukoglu

The scarcity of annotated medical images is a major bottleneck in developing learning models for medical image analysis. Hence, recent studies have focused on pretrained models with fewer annotation requirements that can be fine-tuned for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jonghun Kim , Mansu Kim , Hyunjin Park

Magnetic Resonance Imaging (MRI) typically recruits multiple sequences (defined here as "modalities"). As each modality is designed to offer different anatomical and functional clinical information, there are evident disparities in the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Chengjia Wang , Guang Yang , Giorgos Papanastasiou

Radiological analysis increasingly benefits from pretrained visual representations that can support heterogeneous downstream tasks across imaging modalities. In this work, we introduce OmniRad, a self-supervised radiological foundation…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Luca Zedda , Andrea Loddo , Cecilia Di Ruberto

Skin diseases impose a substantial burden on global healthcare systems, driven by their high prevalence (affecting up to 70% of the population), complex diagnostic processes, and a critical shortage of dermatologists in resource-limited…

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

The release of large datasets and developments in AI have led to dramatic improvements in decoding methods that reconstruct seen images from human brain activity. We evaluate the prospect of further improving recent decoding methods by…

Neurons and Cognition · Quantitative Biology 2023-12-14 Reese Kneeland , Jordyn Ojeda , Ghislain St-Yves , Thomas Naselaris

Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yongrui Yu , Yannian Gu , Shaoting Zhang , Xiaofan Zhang

Magnetic Resonance Imaging (MRI) is widely used in clinical practice, but suffered from prolonged acquisition time. Although deep learning methods have been proposed to accelerate acquisition and demonstrate promising performance, they rely…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Hao Zhang , Qi Wang , Jian Sun , Zhijie Wen , Jun Shi , Shihui Ying

The human brain has immense learning capabilities at extreme energy efficiencies and scale that no artificial system has been able to match. For decades, reverse engineering the brain has been one of the top priorities of science and…

Medical image segmentation is crucial for clinical decision-making, but the scarcity of annotated data presents significant challenges. Few-shot segmentation (FSS) methods show promise but often require training on the target domain and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Lin Zhao , Xiao Chen , Eric Z. Chen , Yikang Liu , Terrence Chen , Shanhui Sun

Predicting future brain state from a baseline magnetic resonance image (MRI) is a central challenge in neuroimaging and has important implications for studying neurodegenerative diseases such as Alzheimer's disease (AD). Most existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Ali Farki , Elaheh Moradi , Deepika Koundal , Jussi Tohka

Research studies have shown no qualms about using data driven deep learning models for downstream tasks in medical image analysis, e.g., anatomy segmentation and lesion detection, disease diagnosis and prognosis, and treatment planning.…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Jiahao Huang , Yingying Fang , Yang Nan , Huanjun Wu , Yinzhe Wu , Zhifan Gao , Yang Li , Zidong Wang , Pietro Lio , Daniel Rueckert , Yonina C. Eldar , Guang Yang

Multi-modal image registration plays a critical role in precision medicine but faces challenges from non-linear intensity relationships and local optima. While deep learning models enable rapid inference, they often suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

As large language models (LLMs) continue to revolutionize AI research, there is a growing interest in building large-scale brain foundation models to advance neuroscience. While most existing brain foundation models are pre-trained on…

Neurons and Cognition · Quantitative Biology 2026-02-11 Xinxu Wei , Kanhao Zhao , Yong Jiao , Lifang He , Yu Zhang

Brain lesion segmentation plays an essential role in neurological research and diagnosis. As brain lesions can be caused by various pathological alterations, different types of brain lesions tend to manifest with different characteristics…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Xinru Zhang , Ni Ou , Berke Doga Basaran , Marco Visentin , Mengyun Qiao , Renyang Gu , Cheng Ouyang , Yaou Liu , Paul M. Matthew , Chuyang Ye , Wenjia Bai

To make sense of their surroundings, intelligent systems must transform complex sensory inputs to structured codes that are reduced to task-relevant information such as object category. Biological agents achieve this in a largely autonomous…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Robin Weiler , Matthias Brucklacher , Cyriel M. A. Pennartz , Sander M. Bohté

Deep learning has revolutionized medical image registration by achieving unprecedented speeds, yet its clinical application is hindered by a limited ability to generalize beyond the training domain, a critical weakness given the typically…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Fengting Zhang , Yue He , Qinghao Liu , Yaonan Wang , Xiang Chen , Hang Zhang

Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Zahra Karimaghaloo , Dumitru Fetco , Haz-Edine Assemlal , Hassan Rivaz , Douglas L. Arnold