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The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Foundation models have transformed vision and language by learning general-purpose representations from large-scale unlabeled data, yet 3D medical imaging lacks analogous approaches. Existing self-supervised methods rely on low-level…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yunhe Gao , Yabin Zhang , Chong Wang , Jiaming Liu , Maya Varma , Jean-Benoit Delbrouck , Akshay Chaudhari , Curtis Langlotz

Vision foundation models (VFMs) trained on large-scale image datasets provide high-quality features that have significantly advanced 2D visual recognition. However, their potential in 3D scene segmentation remains largely untapped, despite…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Karim Knaebel , Kadir Yilmaz , Daan de Geus , Alexander Hermans , David Adrian , Timm Linder , Bastian Leibe

With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

Machine Learning · Computer Science 2026-03-10 Xinxu Wei , Rong Zhou , Lifang He , Yu Zhang

Unsupervised graph representation learning has recently gained interest in several application domains such as neuroscience, where modeling the diverse morphology of cell types in the brain is one of the key challenges. It is currently…

Machine Learning · Statistics 2023-07-12 Marissa A. Weis , Laura Hansel , Timo Lüddecke , Alexander S. Ecker

Reconstructing perceived images from human brain activity forms a crucial link between human and machine learning through Brain-Computer Interfaces. Early methods primarily focused on training separate models for each individual to account…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Zhibo Tian , Ruijie Quan , Fan Ma , Kun Zhan , Yi Yang

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Multi-modal MRIs are widely used in neuroimaging applications since different MR sequences provide complementary information about brain structures. Recent works have suggested that multi-modal deep learning analysis can benefit from…

Computer Vision and Pattern Recognition · Computer Science 2021-06-14 Jiahong Ouyang , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao , Greg Zaharchuk

The rapid growth of medical imaging has fueled the development of Foundation Models (FMs) to reduce the growing, unsustainable workload on radiologists. While recent FMs have shown the power of large-scale pre-training to CT and MRI…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Antoine Saporta , Baptiste Callard , Corentin Dancette , Julien Khlaut , Charles Corbière , Leo Butsanets , Amaury Prat , Pierre Manceron

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

Recent advances in self-supervised learning (SSL) have revolutionized computer vision through innovative architectures and learning objectives, yet they have not fully leveraged insights from biological visual processing systems. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Makoto Yamada , Kian Ming A. Chai , Ayoub Rhim , Satoki Ishikawa , Mohammad Sabokrou , Yao-Hung Hubert Tsai

In this work we investigate the viability of foundational AI/ML models for Synthetic Aperture Radar (SAR) object recognition tasks. We are inspired by the tremendous progress being made in the wider community, particularly in the natural…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Nathan Inkawhich

Human perception plays a vital role in forming beliefs and understanding reality. A deeper understanding of brain functionality will lead to the development of novel deep neural networks. In this work, we introduce a novel framework named…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Xuan-Bac Nguyen , Xin Li , Pawan Sinha , Samee U. Khan , Khoa Luu

Recent breakthroughs in artificial intelligence (AI) are reshaping the way we construct computational counterparts of the brain, giving rise to a new class of ``surrogate brains''. In contrast to conventional hypothesis-driven biophysical…

Neurons and Cognition · Quantitative Biology 2025-10-14 Yinuo Zhang , Demao Liu , Zhichao Liang , Jiani Cheng , Kexin Lou , Jinqiao Duan , Ting Gao , Bin Hu , Quanying Liu

Despite recent advances in medical image generation, existing methods struggle to produce anatomically plausible 3D structures. In synthetic brain magnetic resonance images (MRIs), characteristic fissures are often missing, and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Fabian Bongratz , Yitong Li , Sama Elbaroudy , Christian Wachinger

Ultrasound imaging is widely used in clinical diagnosis due to its non-invasive nature and real-time capabilities. However, traditional ultrasound diagnostics relies heavily on physician expertise and is often hampered by suboptimal image…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Yuncheng Jiang , Chun-Mei Feng , Jinke Ren , Jun Wei , Zixun Zhang , Yiwen Hu , Yunbi Liu , Rui Sun , Xuemei Tang , Juan Du , Xiang Wan , Yong Xu , Bo Du , Xin Gao , Guangyu Wang , Shaohua Zhou , Shuguang Cui , Zhen Li

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Brain computer interface (BCI) research, as well as increasing portions of the field of neuroscience, have found success deploying large-scale artificial intelligence (AI) pre-training methods in conjunction with vast public repositories of…

Neurons and Cognition · Quantitative Biology 2025-06-03 Mattson Ogg , Rahul Hingorani , Diego Luna , Griffin W. Milsap , William G. Coon , Clara A. Scholl

Foundation models, trained on vast amounts of data using self-supervised techniques, have emerged as a promising frontier for advancing artificial intelligence (AI) applications in medicine. This study evaluates three different…

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