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Brain network analysis provides an interpretable framework for characterizing brain organization and has been widely used for neurological disorder identification. Recent advances in self-supervised learning have motivated the development…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jiaxing Xu , Jingying Ma , Xin Lin , Yuxiao Liu , Kai He , Qika Lin , Yiping Ke , Yang Li , Dinggang Shen , Mengling Feng

Functional MRI (fMRI) is crucial for studying brain function and diagnosing neurological disorders. However, existing analysis methods suffer from reproducibility and transferability challenges due to complex preprocessing pipelines and…

While foundation models have achieved remarkable results across a diversity of domains, they still rely on human-generated data, such as text, as a fundamental source of knowledge. However, this data is ultimately the product of human…

Neurons and Cognition · Quantitative Biology 2026-01-21 Maël Donoso

Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features…

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Current fMRI foundation models primarily rely on a limited range of brain states and mismatched pretraining tasks, restricting their ability to learn generalized representations across diverse brain states. We present \textit{Brain-DiT}, a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Junfeng Xia , Wenhao Ye , Xuanye Pan , Xinke Shen , Mo Wang , Quanying Liu

Deep neural networks have been extensively studied for undersampled MRI reconstruction. While achieving state-of-the-art performance, they are trained and deployed specifically for one anatomy with limited generalization ability to another…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Xinwen Liu , Jing Wang , Feng Liu , S. Kevin Zhou

Brain-to-image decoding has been recently propelled by the progress in generative AI models and the availability of large ultra-high field functional Magnetic Resonance Imaging (fMRI). However, current approaches depend on complicated…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Marlène Careil , Yohann Benchetrit , Jean-Rémi King

In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears. However, clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Valentin Koch , Sophia J. Wagner , Salome Kazeminia , Ece Sancar , Matthias Hehr , Julia Schnabel , Tingying Peng , Carsten Marr

Retinal foundation models aim to learn generalizable representations from diverse retinal images, facilitating label-efficient model adaptation across various ophthalmic tasks. Despite their success, current retinal foundation models are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Kai Yu , Yang Zhou , Yang Bai , Zhi Da Soh , Xinxing Xu , Rick Siow Mong Goh , Ching-Yu Cheng , Yong Liu

The widespread use of Magnetic Resonance Imaging (MRI) in combination with deep learning shows promise for many high-impact automated diagnostic and prognostic tools. However, training new models requires large amounts of labeled data, a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Haoyu Dong , Yuwen Chen , Hanxue Gu , Nicholas Konz , Yaqian Chen , Qihang Li , Maciej A. Mazurowski

Synthetic neuroimaging data can mitigate critical limitations of real-world datasets, including the scarcity of rare phenotypes, domain shifts across scanners, and insufficient longitudinal coverage. However, existing generative models…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Fabian Bongratz , Yitong Li , Sama Elbaroudy , Christian Wachinger

Purpose: Depth estimation in robotic surgery is vital in 3D reconstruction, surgical navigation and augmented reality visualization. Although the foundation model exhibits outstanding performance in many vision tasks, including depth…

Computer Vision and Pattern Recognition · Computer Science 2024-01-15 Beilei Cui , Mobarakol Islam , Long Bai , Hongliang Ren

Artificial intelligence applied to retinal images offers significant potential for recognizing signs and symptoms of retinal conditions and expediting the diagnosis of eye diseases and systemic disorders. However, developing generalized…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Boa Jang , Youngbin Ahn , Eun Kyung Choe , Chang Ki Yoon , Hyuk Jin Choi , Young-Gon Kim

There is substantial interest in developing artificial intelligence systems to support radiologists across tasks ranging from segmentation to report generation. Existing computed tomography (CT) foundation models have largely focused on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Rubén Moreno-Aguado , Alba Magallón , Victor Moreno , Yingying Fang , Guang Yang

Medical image analysis frequently encounters data scarcity challenges. Transfer learning has been effective in addressing this issue while conserving computational resources. The recent advent of foundational models like the DINOv2, which…

Image and Video Processing · Electrical Eng. & Systems 2024-02-14 Yuning Huang , Jingchen Zou , Lanxi Meng , Xin Yue , Qing Zhao , Jianqiang Li , Changwei Song , Gabriel Jimenez , Shaowu Li , Guanghui Fu

An important task in image processing and neuroimaging is to extract quantitative information from the acquired images in order to make observations about the presence of disease or markers of development in populations. Having a…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , Andrew J. Plassard , Larry T. Davis , Allen T. Newton , Susan M Resnick , Bennett A. Landman

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Medical foundation models, pre-trained with large-scale clinical data, demonstrate strong performance in diverse clinically relevant applications. RETFound, trained on nearly one million retinal images, exemplifies this approach in…

Recent rapid progress in the field of computational pathology has been enabled by foundation models. These models are beginning to move beyond encoding image patches towards whole-slide understanding but their clinical utility remains…

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