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At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care…

While large language models (LLMs) have shown promise in diagnostic dialogue, their capabilities for effective management reasoning - including disease progression, therapeutic response, and safe medication prescription - remain…

Large language models (LLMs) have shown remarkable progress in encoding clinical knowledge and responding to complex medical queries with appropriate clinical reasoning. However, their applicability in subspecialist or complex medical…

Recent work has demonstrated the promise of conversational AI systems for diagnostic dialogue. However, real-world assurance of patient safety means that providing individual diagnoses and treatment plans is considered a regulated activity…

The scarcity of subspecialist medical expertise, particularly in rare, complex and life-threatening diseases, poses a significant challenge for healthcare delivery. This issue is particularly acute in cardiology where timely, accurate…

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

Artificial Intelligence · Computer Science 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Artificial intelligence (AI) has demonstrated strong potential in clinical diagnostics, often achieving accuracy comparable to or exceeding that of human experts. A key challenge, however, is that AI reasoning frequently diverges from…

Artificial Intelligence · Computer Science 2026-05-25 Belona Sonna , Alban Grastien

Artificial intelligence has shown promise in medical imaging, yet most existing systems lack flexibility, interpretability, and adaptability - challenges especially pronounced in ophthalmology, where diverse imaging modalities are…

We present PULSE, a medical reasoning agent that combines a domain-tuned large language model with scientific literature retrieval to support diagnostic decision-making in complex real-world cases. To evaluate its capabilities, we curated a…

Computation and Language · Computer Science 2026-03-19 Zhongzhen Huang , Yan Ling , Hong Chen , Ye Feng , Li Wu , Linjie Mu , Shaoting Zhang , Xiaofan Zhang , Kun Qian , Xiaomu Li

Clinician skepticism toward opaque AI hinders adoption in high-stakes healthcare. We present AICare, an interactive and interpretable AI copilot for collaborative clinical decision-making. By analyzing longitudinal electronic health…

Human-Computer Interaction · Computer Science 2026-02-03 Yinghao Zhu , Dehao Sui , Zixiang Wang , Xuning Hu , Lei Gu , Yifan Qi , Tianchen Wu , Ling Wang , Yuan Wei , Wen Tang , Zhihan Cui , Yasha Wang , Lequan Yu , Ewen M Harrison , Junyi Gao , Liantao Ma

Bias in medical artificial intelligence is conventionally viewed as a defect requiring elimination. However, human reasoning inherently incorporates biases shaped by education, culture, and experience, suggesting their presence may be…

Artificial Intelligence · Computer Science 2026-03-05 Farhad Abtahi , Mehdi Astaraki , Fernando Seoane

Human-AI complementarity is the claim that a human supported by an AI system can outperform either alone in a decision-making process. Since its introduction in the humanAI interaction literature, it has gained traction by generalizing the…

Artificial Intelligence · Computer Science 2026-04-23 Andrea Ferrario , Alessandro Facchini , Juan M. Durán

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

This study investigates clinicians' perceptions and attitudes toward an assistive artificial intelligence (AI) system that employs a speech-based explainable ML algorithm for detecting depression. The AI system detects depression from…

Human-Computer Interaction · Computer Science 2024-10-25 Kexin Feng , Theodora Chaspari

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Artificial intelligence (AI) has gained significant attention in healthcare consultation due to its potential to improve clinical workflow and enhance medical communication. However, owing to the complex nature of medical information, large…

Computation and Language · Computer Science 2024-03-05 Xiaolan Chen , Ziwei Zhao , Weiyi Zhang , Pusheng Xu , Le Gao , Mingpu Xu , Yue Wu , Yinwen Li , Danli Shi , Mingguang He

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas
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