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Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Systems and Control · Electrical Eng. & Systems 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

Parkinsons disease (PD) alters cortical neural dynamics, yet reliable non-invasive electrophysiological biomarkers remain elusive. This study examined whether interpretable EEG features capturing complementary aspects of neural dynamics can…

Neurons and Cognition · Quantitative Biology 2026-04-14 Antonios G. Dougalis

Electropermeabilization is a clinical technique in cancer treatment to locally stimulate the cell metabolism. It is based on electrical fields that change the properties of the cell membrane. With that, cancer treatment can reach the cell…

Analysis of PDEs · Mathematics 2016-03-03 Habib Ammari , Thomas Widlak , Wenlong Zhang

For decades, focal non-invasive neuromodulation of deep brain regions has not been possible because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic…

Neurons and Cognition · Quantitative Biology 2025-12-17 Pierre Vassiliadis , Elena Beanato , Maximilian J. Wessel , Friedhelm C. Hummel

Transcranial magnetic stimulation (TMS) is a noninvasive medical procedure that can modulate brain activity, and it is widely used in neuroscience and neurology research. Compared to manual operators, robots may improve the outcome of TMS…

Extracellular electrical potentials (EEP) recorded from the brain are an active manifestation of all cellular processes that propagate within a volume of brain tissue. A standard approach for their quantification are power spectral analyses…

Neurons and Cognition · Quantitative Biology 2020-11-17 Shailaja Akella , Ali Mohebi , Kiersten Riels , Andreas Keil , Karim Oweiss , Jose C. Principe

Transcranial direct current stimulation (tDCS) is known to have a modulatory effect on neural tissue and that it is polarity specific. It is also shown that tDCS demonstrated the lasting effect in therapeutic applications. The main aim of…

Neurons and Cognition · Quantitative Biology 2018-12-05 Milena Cukic , Miodrag Stokic , Slavoljub Radenkovic , Milos Ljubisavljevic , Dragoljub Donald Pokrajac

Electroencephalography (EEG) monitors ---by either intrusive or noninvasive electrodes--- time and frequency variations and spectral content of voltage fluctuations or waves, known as brain rhythms, which in some way uncover activity during…

Neurons and Cognition · Quantitative Biology 2019-03-13 Javier A. Galadí , Joaquín J. Torres , J. Marro

Learning universal representations from electroencephalogram (EEG) signals is a cutting-edge approach in the field of neuroinformatics and brain-computer interfaces (BCIs). Conventionally, EEG is treated as a multivariate temporal signal,…

Machine Learning · Computer Science 2026-05-20 Xinyang Tian , Ruitao Liu , Ziyi Ye , Siyang Xue , Xin Wang , Xuesong Chen

Proton minibeam (pMB) radiotherapy, delivers highly heterogeneous dose distributions alternating high-dose peaks and low-dose valleys. This aims to widen the therapeutic window by improving normal tissue sparing while maintaining the same…

For whole-body (WB) kinetic modeling based on a typical PET scanner, a multi-pass multi-bed scanning protocol is necessary given the limited axial field-of-view. Such a protocol introduces loss of early-dynamics in time-activity curves…

Medical Physics · Physics 2024-05-14 Kyung-Nam Lee , Arman Rahmim , Carlos Uribe

During brain function, groups of neurons fire synchronously. When these groups are large enough, the resulting electrical signals can be measured on the scalp using Electroencephalography (EEG). The amplitude of these signals can be…

Neurons and Cognition · Quantitative Biology 2025-02-05 Jesus Acosta-Elias , Santiago Mendez-Moreno , Omar Vital-Ochoa , Ricardo Espinosa-Tanguma

Pain is a complex and pervasive condition that affects a significant portion of the population. Accurate and consistent assessment is essential for individuals suffering from pain, as well as for developing effective management strategies…

Artificial Intelligence · Computer Science 2025-09-17 Stefanos Gkikas , Ioannis Kyprakis , Manolis Tsiknakis

Autonomous implantable bioelectronics rely on wireless connectivity, necessitating highly efficient electromagnetic (EM) radiation systems. However, limitations in power, safety, and data transmission currently impede the advancement of…

Biological Physics · Physics 2026-02-17 Mingxiang Gao , Denys Nikolayev , Zvonimir Sipus , Anja K. Skrivervik

Electromagnetic stimulation of the human brain is a key tool for the neurophysiological characterization and diagnosis of several neurological disorders. Transcranial magnetic stimulation (TMS) is one procedure that is commonly used…

Machine Learning · Computer Science 2020-02-04 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Recent advances in biosensors technology and mobile electroencephalographic (EEG) interfaces have opened new application fields for cognitive monitoring. A computable biomarker for the assessment of spontaneous aesthetic brain responses…

Neurons and Cognition · Quantitative Biology 2016-09-26 Dimitrios A. Adamos , Stavros I. Dimitriadis , Nikolaos A. Laskaris

A core goal of functional neuroimaging is to study how the environment is processed in the brain. The mainstream paradigm involves concurrently measuring a broad spectrum of brain responses to a small set of environmental features…

Neurons and Cognition · Quantitative Biology 2021-06-14 Pedro F. da Costa , Rianne Haartsen , Elena Throm , Luke Mason , Anna Gui , Robert Leech , Emily J. H. Jones

The electrocardiogram (ECG) follows a characteristic shape, which has led to the development of several mathematical models for extracting clinically important information. Our main objective is to resolve limitations of previous…

Signal Processing · Electrical Eng. & Systems 2021-09-28 Carl Böck , Péter Kovács , Pablo Laguna , Jens Meier , Mario Huemer

EEG microstate analysis segments continuous brain electrical activity into brief, quasi-stable topographic configurations that reflect discrete functional brain states. Conventional approaches such as Modified K-Means operate directly in…

Machine Learning · Computer Science 2026-05-15 Saheed Faremi , Andrea Visentin , Luca Longo

Electroencephalographic neurofeedback (EEG-NF) has been proposed as a promising technique to modulate brain activity through real-time EEG-based feedback. Alpha neurofeedback in particular is believed to induce rapid self-regulation of…

Neurons and Cognition · Quantitative Biology 2025-09-15 Jacob Maaz , Laurent Waroquier , Alexandra Dia , Véronique Paban , Arnaud Rey