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Large Language Model-based Multi-Agent Systems (LLM-MAS) have revolutionized complex problem-solving capability by enabling sophisticated agent collaboration through message-based communications. While the communication framework is crucial…

Cryptography and Security · Computer Science 2025-06-03 Pengfei He , Yupin Lin , Shen Dong , Han Xu , Yue Xing , Hui Liu

Large Language Models (LLMs) have demonstrated remarkable capabilities in various reasoning and generation tasks. However, their proficiency in complex causal reasoning, discovery, and estimation remains an area of active development, often…

Artificial Intelligence · Computer Science 2025-09-03 Adib Bazgir , Amir Habibdoust , Yuwen Zhang , Xing Song

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

Multi-agent systems (MAS) powered by Large Language Models (LLMs) have been demonstrated to push the boundaries of LLM capabilities, yet they often incur significant costs and face challenges in dynamic LLM selection. Current LLM routing…

Machine Learning · Computer Science 2025-02-18 Yanwei Yue , Guibin Zhang , Boyang Liu , Guancheng Wan , Kun Wang , Dawei Cheng , Yiyan Qi

Understanding how humans collaborate and communicate in teams is essential for improving human-agent teaming and AI-assisted decision-making. However, relying solely on data from large-scale user studies is impractical due to logistical,…

With the rapid progress of large language models (LLMs), LLM-powered multi-agent systems (MAS) are drawing increasing interest across academia and industry. However, many current MAS frameworks struggle with reliability and scalability,…

Multiagent Systems · Computer Science 2025-11-04 Yang Li , Siqi Ping , Xiyu Chen , Xiaojian Qi , Zigan Wang , Ye Luo , Xiaowei Zhang

Large language model-based multi-agent systems have recently gained significant attention due to their potential for complex, collaborative, and intelligent problem-solving capabilities. Existing surveys typically categorize LLM-based…

Multiagent Systems · Computer Science 2026-05-27 Bingyu Yan , Zhibo Zhou , Litian Zhang , Lian Zhang , Ziyi Zhou , Dezhuang Miao , Zhoujun Li , Chaozhuo Li , Xiaoming Zhang

Agent-based modeling approaches represent the state-of-art in modeling travel demand and transportation system dynamics and are valuable tools for transportation planning. However, established agent-based approaches in transportation rely…

Multiagent Systems · Computer Science 2025-04-01 Tianming Liu , Jirong Yang , Yafeng Yin

In autonomic computing, self-adaptation has been proposed as a fundamental paradigm to manage the complexity of multiagent systems (MASs). This achieved by extending a system with support to monitor and adapt itself to achieve specific…

Multiagent Systems · Computer Science 2023-07-13 Nathalia Nascimento , Paulo Alencar , Donald Cowan

Large language model-based multi-agent systems have shown great abilities across various tasks due to the collaboration of expert agents, each focusing on a specific domain. However, the impact of clumsy or even malicious agents--those who…

Artificial Intelligence · Computer Science 2025-05-30 Jen-tse Huang , Jiaxu Zhou , Tailin Jin , Xuhui Zhou , Zixi Chen , Wenxuan Wang , Youliang Yuan , Michael R. Lyu , Maarten Sap

Mass casualty incidents (MCIs) overwhelm healthcare systems and demand rapid, accurate patient-hospital allocation decisions under extreme pressure. Here, we developed and validated a deep reinforcement learning-based decision-support AI…

Machine Learning · Computer Science 2025-09-11 Zhaoxun "Lorenz" Liu , Wagner H. Souza , Jay Han , Amin Madani

Multi-agent systems (MAS) built on large language models (LLMs) offer a promising path toward solving complex, real-world tasks that single-agent systems often struggle to manage. While recent advancements in test-time scaling (TTS) have…

Artificial Intelligence · Computer Science 2025-08-20 Can Jin , Hongwu Peng , Qixin Zhang , Yujin Tang , Dimitris N. Metaxas , Tong Che

Large language models (LLMs) have revolutionized medical reasoning tasks, yet single-agent systems often falter on complex, interdisciplinary problems requiring robust handling of uncertainty and conflicting evidence. Multi-agent systems…

Artificial Intelligence · Computer Science 2026-05-29 Xiaoyang Wang , Christopher C. Yang

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

The emergence of Large Language Models (LLMs) is rapidly accelerating the development of autonomous multi-agent systems (MAS), paving the way for the Internet of Agents. However, traditional centralized MAS architectures present significant…

Multiagent Systems · Computer Science 2025-12-03 Yepeng Ding , Ahmed Twabi , Junwei Yu , Lingfeng Zhang , Tohru Kondo , Hiroyuki Sato

The fast development of Artificial Intelligence (AI) agents provides a promising way for the realization of intelligent and customized wireless networks. In this paper, we propose a Wireless Multi-Agent System (WMAS), which can provide…

Multiagent Systems · Computer Science 2025-08-04 Jingchen Peng , Dingli Yuan , Boxiang Ren , Jie Fan , Hao Wu , Lu Yang

While Large Language Model (LLM) multi-agent systems (MAS) offer a transformative approach to simulating human behavior in complex systems, it remains largely unexplored whether these simulations can replicate realistic structural and…

Social and Information Networks · Computer Science 2026-05-14 Siqi Miao , Ziyang Chen , Yuhong Luo , Hans Hao-Hsun Hsu , Mufei Li , Kaiqing Zhang , Pan Li
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