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Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Despite enthusiasm for Multi-Agent LLM Systems (MAS), their performance gains on popular benchmarks are often minimal. This gap highlights a critical need for a principled understanding of why MAS fail. Addressing this question requires…

Hierarchical multi-agent systems (HMAS) organize collections of agents into layered structures that help manage complexity and scale. These hierarchies can simplify coordination, but they also can introduce trade-offs that are not always…

Multiagent Systems · Computer Science 2025-08-19 David J. Moore

Psychological support hotlines provide critical support for individuals experiencing mental health emergencies, yet current assessments largely rely on human operators whose judgments may vary with professional experience and are…

Computation and Language · Computer Science 2026-05-12 Terumi Chiba , Yang Luo , Ziyun Cui , Yongsheng Tong , Chao Zhang

Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling. We propose a multi-agent medical QA…

Computation and Language · Computer Science 2026-02-17 Naeimeh Nourmohammadi , Md Meem Hossain , The Anh Han , Safina Showkat Ara , Zia Ush Shamszaman

Large Language Model (LLM) agents have shown promising potential in automating Instructional Systems Design (ISD), a systematic approach to developing educational programs. However, evaluating these agents remains challenging due to the…

Software Engineering · Computer Science 2026-02-12 YoungHoon Jeon , Suwan Kim , Haein Son , Sookbun Lee , Yeil Jeong , Unggi Lee

Recent advances in Large Language Models (LLMs) have catalyzed the development of multi-agent systems (MAS) for complex reasoning tasks. However, existing MAS typically rely on pre-defined or pre-compiled communication topologies, which…

Machine Learning · Computer Science 2026-05-18 Xingjian Wu , Junkai Lu , Siyu Yan , Xiangfei Qiu , Jilin Hu , Chenjuan Guo , Bin Yang

Since the advent of Large Language Models (LLMs), various research based on such models have maintained significant academic attention and impact, especially in AI and robotics. In this paper, we propose a multi-agent framework with LLMs to…

Robotics · Computer Science 2025-05-12 Junhong Chen , Ziqi Yang , Haoyuan G Xu , Dandan Zhang , George Mylonas

Large Language Model-based Multi-Agent Systems (MASs) have emerged as a powerful paradigm for tackling complex tasks through collaborative intelligence. However, the topology of these systems--how agents in MASs should be configured,…

Multiagent Systems · Computer Science 2025-10-20 Jiaxi Yang , Mengqi Zhang , Yiqiao Jin , Hao Chen , Qingsong Wen , Lu Lin , Yi He , Srijan Kumar , Weijie Xu , James Evans , Jindong Wang

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Autonomous agent systems powered by Large Language Models (LLMs) have demonstrated promising capabilities in automating complex tasks. However, current evaluations largely rely on success rates without systematically analyzing the…

Artificial Intelligence · Computer Science 2025-08-19 Ruofan Lu , Yichen Li , Yintong Huo

Agentic AI systems are increasingly capable of autonomous data science workflows, yet clinical prediction tasks demand domain expertise that purely automated approaches struggle to provide. We investigate how human guidance of agentic AI…

Large language model (LLM)-based multi-agent systems have emerged as a powerful paradigm for enabling autonomous agents to solve complex tasks. As these systems scale in complexity, cost becomes an important consideration for practical…

Multiagent Systems · Computer Science 2025-11-27 Liming Yang , Junyu Luo , Xuanzhe Liu , Yiling Lou , Zhenpeng Chen

Recent advancements in Large Language Models (LLMs) and related technologies such as Retrieval-Augmented Generation (RAG) and Diagram of Thought (DoT) have enabled the creation of autonomous intelligent systems capable of performing cluster…

Artificial Intelligence · Computer Science 2024-11-11 Honghao Shi , Longkai Cheng , Wenli Wu , Yuhang Wang , Xuan Liu , Shaokai Nie , Weixv Wang , Xuebin Min , Chunlei Men , Yonghua Lin

Rapidly evolving cyberattacks demand incident response systems that can autonomously learn and adapt to changing threats. Prior work has extensively explored the reinforcement learning approach, which involves learning response strategies…

Cryptography and Security · Computer Science 2026-04-16 Yiran Gao , Kim Hammar , Tao Li

The rapid emergence of multi-agent AI systems (MAS), including LangChain, CrewAI, and AutoGen, has shaped how large language model (LLM) applications are developed and orchestrated. However, little is known about how these systems evolve…

Software Engineering · Computer Science 2026-01-13 Daniel Liu , Krishna Upadhyay , Vinaik Chhetri , A. B. Siddique , Umar Farooq

Large language model (LLM)-based multi-agent systems (MAS) show strong promise for complex reasoning, planning, and tool-augmented tasks, but designing effective MAS architectures remains labor-intensive, brittle, and hard to generalize.…

Machine Learning · Computer Science 2026-05-28 Yuntong Hu , Yuting Zhang , Matthew Trager , Yi Zhang , Shuo Yang , Wei Xia , Stefano Soatto

Shortcuts such as APIs and deep-links have emerged as efficient complements to flexible GUI operations, fostering a promising hybrid paradigm for MLLM-based mobile automation. However, systematic evaluation of GUI-shortcut hybrid agents…

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Large Language Model Powered Multi-Agent Systems (MASs) are increasingly employed to automate complex real-world problems, such as programming and scientific discovery. Despite their promising, MASs are not without their flaws. However,…

Software Engineering · Computer Science 2025-09-18 Yu Ge , Linna Xie , Zhong Li , Yu Pei , Tian Zhang
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