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The complete connectome of the Drosophila larva brain offers a unique opportunity to investigate whether biologically evolved circuits can support artificial intelligence. We convert this wiring diagram into a Biological Processing Unit…

Neural and Evolutionary Computing · Computer Science 2025-07-16 Siyu Yu , Zihan Qin , Tingshan Liu , Beiya Xu , R. Jacob Vogelstein , Jason Brown , Joshua T. Vogelstein

Precise engineering of materials and surfaces has been at the heart of some of the recent advances in optics and photonics. These advances around the engineering of materials with new functionalities have also opened up exciting avenues for…

Image and Video Processing · Electrical Eng. & Systems 2021-01-25 Onur Kulce , Deniz Mengu , Yair Rivenson , Aydogan Ozcan

Current computers operate at enormous speeds of ~10^13 bits/s, but their principle of sequential logic operation has remained unchanged since the 1950s. Though our brain is much slower on a per-neuron base (~10^3 firings/s), it is capable…

Emerging Technologies · Computer Science 2015-05-30 Anirban Bandyopadhyay , Ranjit Pati , Satyajit Sahu , Ferdinand Peper , Daisuke Fujita

Here, we introduce a new class of computer which does not use any circuit or logic gate. In fact, no program needs to be written: it learns by itself and writes its own program to solve a problem. Godels incompleteness argument is explored…

Emerging Technologies · Computer Science 2014-01-30 Subrata Ghosh , Krishna Aswani , Surabhi Singh , Satyajit Sahu , Daisuke Fujita , Anirban Bandyopadhyay

Several efforts are currently underway to decipher the connectome or parts thereof in a variety of organisms. Ascertaining the detailed physiological properties of all the neurons in these connectomes, however, is out of the scope of such…

Neurons and Cognition · Quantitative Biology 2014-04-03 Venkatakrishnan Ramaswamy , Arunava Banerjee

We investigate the logical reasoning capabilities of large language models (LLMs) and their scalability in complex non-monotonic reasoning. To this end, we introduce ZebraLogic, a comprehensive evaluation framework for assessing LLM…

Artificial Intelligence · Computer Science 2025-07-16 Bill Yuchen Lin , Ronan Le Bras , Kyle Richardson , Ashish Sabharwal , Radha Poovendran , Peter Clark , Yejin Choi

Neurons, as eukaryotic cells, have powerful internal computation capabilities. One neuron can have many distinct states, and brains can use this capability. Processes of neuron growth and maintenance use chemical signalling between cell…

Neurons and Cognition · Quantitative Biology 2025-12-10 Robert Worden

Translation is one of the most fundamental processes in the biological cell. Because of the central role that translation plays across all domains of life, the enzyme that carries out this process, the ribosome, is required to process…

Quantitative Methods · Quantitative Biology 2023-10-11 Daniel A. Inafuku , Kay L. Kirkpatrick , Onyema Osuagwu , Qier An , David A. Brewster , Mayisha Zeb Nakib

The Physarum network expands or retracts in response to environmental stimuli, demonstrating an intelligent adaptive capability to locate optimal paths for nutrient transport. The underlying physical mechanism governing this intelligence…

Biological Physics · Physics 2026-02-03 Bingyang Han , Luolan Chen , Tieyan Si

Life is confronted with computation problems in a variety of domains including animal behavior, single-cell behavior, and embryonic development. Yet we currently do not know of a naturally existing biological system that is capable of…

Other Quantitative Biology · Quantitative Biology 2022-03-10 Hessameddin Akhlaghpour

The black-box nature of Large Language Models necessitates novel evaluation frameworks that transcend surface-level performance metrics. This study investigates the internal neural representations of cognitive complexity using Bloom's…

Artificial Intelligence · Computer Science 2026-02-20 Bianca Raimondi , Maurizio Gabbrielli

Logical reasoning is central to complex human activities, such as thinking, debating, and planning; it is also a central component of many AI systems as well. In this paper, we investigate the extent to which encoder-only transformer…

Computation and Language · Computer Science 2024-07-02 Paulo Pirozelli , Marcos M. José , Paulo de Tarso P. Filho , Anarosa A. F. Brandão , Fabio G. Cozman

Large Language Models (LLMs) have demonstrated remarkable capabilities across various domains, including software development, education, and technical assistance. Among these, software development is one of the key areas where LLMs are…

Computation and Language · Computer Science 2026-01-07 Inpyo Song , Eunji Jeon , Jangwon Lee

Many dynamical systems found in biology, ranging from genetic circuits to the human brain to human social systems, are inherently computational. Although extensive research has explored their resulting functions and behaviors, the…

Neurons and Cognition · Quantitative Biology 2025-04-15 Junang Li , Andrew M. Leifer , David H. Wolpert

The cerebellum is implicated in nearly every domain of human cognition, yet our understanding of how this subcortical structure contributes to cognition remains elusive. Efforts on this front have tended to fall into one of two camps. On…

Neurons and Cognition · Quantitative Biology 2025-09-15 Jonathan Tsay , Richard Ivry

This paper describes a scalable active learning pipeline prototype for large-scale brain mapping that leverages high performance computing power. It enables high-throughput evaluation of algorithm results, which, after human review, are…

Multifunctionality describes the capacity for a neural network to perform multiple mutually exclusive tasks without altering its network connections; and is an emerging area of interest in the reservoir computing machine learning paradigm.…

Machine Learning · Computer Science 2023-06-06 Jacob Morra , Andrew Flynn , Andreas Amann , Mark Daley

This work examines the interconnections between logic, epistemology, and sciences within the Naturalist tradition. It presents a scheme that connects logic, mathematics, physics, chemistry, biology, and cognition, emphasizing…

Other Computer Science · Computer Science 2023-09-26 Gordana Dodig-Crnkovic

Collective movement occurs in living systems where the simple movements of individual members of a pop- ulation are combined to generate movement of the collective as a whole, displaying complex dynamics which cannot be found in the…

Emerging Technologies · Computer Science 2015-11-25 Jeff Jones

Weighted knowledge bases for description logics with typicality under a "concept-wise" multi-preferential semantics provide a logical interpretation of MultiLayer Perceptrons. In this context, Answer Set Programming (ASP) has been shown to…

Artificial Intelligence · Computer Science 2023-03-28 Mario Alviano , Laura Giordano , Daniele Theseider Dupré
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