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A supply chain is a system which moves products from a supplier to customers. The supply chains are ubiquitous. They play a key role in all economic activities. Inspired by biological principles of nutrients' distribution in protoplasmic…

Neural and Evolutionary Computing · Computer Science 2014-03-24 Xiaoge Zhang , Andrew Adamatzky , Xin-She Yang , Hai Yang , Sankaran Mahadevan , Yong Deng

Plasmodium stage of Physarum polycephalum behaves as a distributed dynamical pattern formation mechanism who's foraging and migration is influenced by local stimuli from a wide range of attractants and repellents. Complex protoplasmic tube…

Biological Physics · Physics 2012-04-10 Soichiro Tsuda , Jeff Jones , Andrew Adamatzky , Jonathan Mills

Acellular slime mould Physarum polycephalum is a popular now user-friendly living substrate for designing of future and emergent sensing and computing devices. P. polycephalum exhibits regular patterns of oscillations of its surface…

Emerging Technologies · Computer Science 2013-12-17 Andrew Adamatzky

Active fluid transport is a hallmark of many biological transport networks. While animal circulatory systems generally rely on a single heart to drive flows, other organisms employ decentralized local pumps to distribute fluids and…

Biological Physics · Physics 2024-01-04 Adam B. Dionne , Katharine E. Jensen , Henrik Ronellenfitsch

We experimentally derived a unique one-to-one mapping between a range of selected bioactive chemicals and patterns of oscillations of the slime mould's extacellular electrical potential.

Emerging Technologies · Computer Science 2013-12-17 James G. H. Whiting , Ben P. J. de Lacy Costello , Andrew Adamatzky

A dynamic self-organized morphology is the hallmark of network-shaped organisms like slime moulds and fungi. Organisms continuously re-organize their flexible, undifferentiated body plans to forage for food. Among these organisms the slime…

Biological Physics · Physics 2019-03-27 Karen Alim

Living substrates are capable for nontrivial mappings of electrical signals due to the substrate nonlinear electrical characteristics. This property can be used to realise Boolean functions. Input logical values are represented by amplitude…

Emerging Technologies · Computer Science 2021-08-12 Nic Roberts , Andrew Adamatzky

While vision-language models (VLMs) have demonstrated promising capabilities in reasoning and planning for embodied agents, their ability to comprehend physical phenomena, particularly within structured 3D environments, remains severely…

Biological information processing manifests a huge variety in its complexity and capability among different organisms, which presumably stems from the evolutionary optimization under limited computational resources. Starting from the…

Biological Physics · Physics 2025-10-21 Takehiro Tottori , Tetsuya J. Kobayashi

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

In this paper the authors extend [1] and provide more details of how the brain may act like a quantum computer. In particular, positing the difference between voltages on two axons as the environment for ions undergoing spatial…

Neurons and Cognition · Quantitative Biology 2022-11-15 Aman Chawla , Salvatore Domenic Morgera

In this work we study and expand a model describing the dynamics of a unicellular slime mold, Physarum Polycephalum (PP), which was proposed to simulate the ability of PP to find the shortest path connecting two food sources in a maze. The…

Numerical Analysis · Mathematics 2020-09-29 Enrico Facca , Franco Cardin , Mario Putti

We investigate flow-driven amoeboid motility as exhibited by microplasmodia of Physarum polycephalum. A poroelastic two-phase model with rigid boundaries is extended to the case of free boundaries and substrate friction. The cytoskeleton is…

Soft Condensed Matter · Physics 2018-11-14 Dirk Alexander Kulawiak , Jakob Löber , Markus Bär , Harald Engel

Optimization of fluid transport in the slime mold Physarum polycephalum has been the subject of several modeling efforts in recent literature. Existing models assume that the tube adaptation mechanism in P. polycephalum's tubular network is…

Tissues and Organs · Quantitative Biology 2019-07-01 Vincenzo Bonifaci

Neuromorphic networks of artificial neurons and synapses can solve computational hard problems with energy efficiencies unattainable for von Neumann architectures. For image processing, silicon neuromorphic processors outperform graphic…

Emerging Technologies · Computer Science 2018-11-08 Wei Yi , Kenneth K. Tsang , Stephen K. Lam , Xiwei Bai , Jack A. Crowell , Elias A. Flores

The enormous energy demand of artificial intelligence is driving the development of alternative hardware for deep learning. Physical neural networks try to exploit physical systems to perform machine learning more efficiently. In…

Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division. These flows are driven by organized contractions of the actomyosin cortex. In order to…

Adaptation and Self-Organizing Systems · Physics 2022-07-29 Busson Valentin , Saiseau Raphaël , Durand Marc

The ultimate limits of computation are not just logical, but physical. We investigate the physical resources -- time, energy, entropy, and free energy -- required to perform computational work. We apply the resulting measures of physical…

Quantum Physics · Physics 2025-06-23 Michele Reilly , Seth Lloyd

Living organisms survive and multiply even though they have uncertain and incomplete information about their environment and imperfect models to predict the consequences of their actions. Bayesian models have been proposed to face this…

Emerging Technologies · Computer Science 2015-11-13 Jacques Droulez , David Colliaux , Audrey Houillon , Pierre Bessière

Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a…

Quantitative Methods · Quantitative Biology 2017-10-25 Felix Bäuerle , Mirna Kramar , Karen Alim