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In this study, the performance of existing U-shaped neural network architectures was enhanced for medical image segmentation by adding Transformer. Although Transformer architectures are powerful at extracting global information, its…

Image and Video Processing · Electrical Eng. & Systems 2024-04-12 Songkai Sun , Qingshan She , Yuliang Ma , Rihui Li , Yingchun Zhang

While modern segmentation models often prioritize performance over practicality, we advocate a design philosophy prioritizing simplicity and efficiency, and attempted high performance segmentation model design. This paper presents…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Xiang Yu , Yayan Chen , Guannan He , Qing Zeng , Yue Qin , Meiling Liang , Dandan Luo , Yimei Liao , Zeyu Ren , Cheng Kang , Delong Yang , Bocheng Liang , Bin Pu , Ying Yuan , Shengli Li

Foundation models promise to unify multiple clinical tasks within a single framework, but recent ultrasound studies report that unified models can underperform task-specific baselines. We hypothesize that this degradation arises not from…

Image and Video Processing · Electrical Eng. & Systems 2026-05-25 Fangyijie Wang , Tanya Akumu , Vien Ngoc Dang , Amelia Jiménez-Sánchez , Jieyun Bai , Guénolé Silvestre , Karim Lekadir , Kathleen M. Curran

Vision-Language Foundation Models (VLFMs) exhibit remarkable generalization, yet their direct application to medical ultrasound is severely hindered by a profound modality gap. The unique acoustic physics of ultrasound, characterized by…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Jingguo Qu , Xinyang Han , Jia Ai , Juan Wu , Tong Zhao , Tonghuan Xiao , Sheng Ning , Yuqi Yang , Jing Qin , Ann Dorothy King , Winnie Chiu-Wing Chu , Jing Cai , Michael Tin-Cheung Ying

Light sheet fluorescence microscopy (LSM) enables high-resolution, three-dimensional (3D) imaging of biological specimens, providing rich volumetric data for studying cellular organization, pathology, and vascular networks. However, the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Adina Scheinfeld , Haotan Zhang , Shang Mu , Rudolf L. M. van Herten , Lucas Stoffl , Ali Erturk , Zhuhao Wu , Johannes C. Paetzold

Revealing novel insights from the relationship between molecular measurements and pathology remains a very impactful application of machine learning in biomedicine. Data in this domain typically contain only a few observations but thousands…

Machine Learning · Computer Science 2026-03-31 Christopher Kolberg , Jules Kreuer , Jonas Huurdeman , Sofiane Ouaari , Katharina Eggensperger , Nico Pfeifer

In recent years, the advent of foundation models (FM) for digital pathology has relied heavily on scaling the pre-training datasets and the model size, yielding large and powerful models. While it resulted in improving the performance on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Alexandre Filiot , Nicolas Dop , Oussama Tchita , Auriane Riou , Rémy Dubois , Thomas Peeters , Daria Valter , Marin Scalbert , Charlie Saillard , Geneviève Robin , Antoine Olivier

During raw-data acquisition in CT imaging, diverse factors can degrade the collected sinograms, with undersampling and noise leading to severe artifacts and noise in reconstructed images and compromising diagnostic accuracy. Conventional…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xingyu Ai , Shaoyu Wang , Zhiyuan Jia , Ao Xu , Hongming Shan , Jianhua Ma , Qiegen Liu

Generative models have achieved remarkable progress with the emergence of flow matching (FM). It has demonstrated strong generative capabilities and attracted significant attention as a simulation-free flow-based framework capable of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Huynh Trinh Ngoc , Hoang Anh Nguyen Kim , Toan Nguyen Hai , Long Tran Quoc

Despite significant strides in medical foundation models, the ultrasound domain lacks a comprehensive solution capable of bridging low-level Ultrasound Grounded Perception (e.g., segmentation, localization) and high-level Ultrasound…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Dengbo Chen , Ziwei Zhao , Kexin Zhang , Shishuang Zhao , Junjie Hou , Yaqian Wang , Nianxi Liao , Anlan Sun , Fei Gao , Jia Ding , Yuhang Liu , Dong Wang

Accurate medical image segmentation is essential for clinical diagnosis and treatment planning. While recent interactive foundation models (e.g., nnInteractive) enhance generalization through large-scale multimodal pretraining, they still…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Ziyu Zhang , Yi Yu , Simeng Zhu , Ahmed Aly , Yunhe Gao , Ning Gu , Yuan Xue

Most state-of-the-art techniques for medical image segmentation rely on deep-learning models. These models, however, are often trained on narrowly-defined tasks in a supervised fashion, which requires expensive labeled datasets. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Heejong Kim , Victor Ion Butoi , Adrian V. Dalca , Daniel J. A. Margolis , Mert R. Sabuncu

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation),…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Weiming Chen , Xitong Ling , Xidong Wang , Zhenyang Cai , Yijia Guo , Mingxi Fu , Ziyi Zeng , Minxi Ouyang , Jiawen Li , Yizhi Wang , Tian Guan , Benyou Wang , Yonghong He

Purpose: Prenatal ultrasound is a key tool in evaluating fetal structural development and detecting abnormalities, contributing to reduced perinatal complications and improved neonatal survival. Accurate identification of standard fetal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Shengjun Zhu , Siyu Liu , Runqing Xiong , Liping Zheng , Duo Ma , Rongshang Chen , Jiaxin Cai

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Instead of building…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed

Medical foundation models show promise to learn broadly generalizable features from large, diverse datasets. This could be the base for reliable cross-modality generalization and rapid adaptation to new, task-specific goals, with only a few…

While foundation models in radiology are expected to be applied to various clinical tasks, computational cost constraints remain a major challenge when training on 3D-CT volumetric data. In this study, we propose TotalFM, a radiological…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Kohei Yamamoto , Tomohiro Kikuchi

Current state-of-the-art medical image segmentation methods prioritize accuracy but often at the expense of increased computational demands and larger model sizes. Applying these large-scale models to the relatively limited scale of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jiahui Zhong , Wenhong Tian , Yuanlun Xie , Zhijia Liu , Jie Ou , Taoran Tian , Lei Zhang

Medical Image Foundation Models have proven to be powerful tools for mask prediction across various datasets. However, accurately assessing the uncertainty of their predictions remains a significant challenge. To address this, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Xin Wang , Xiaoyu Liu , Peng Huang , Pu Huang , Shu Hu , Hongtu Zhu

Cytology is essential for cancer diagnostics and screening due to its minimally invasive nature. However, the development of robust deep learning models for digital cytology is challenging due to the heterogeneity in staining and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Vedrana Ivezić , Ashwath Radhachandran , Ekaterina Redekop , Shreeram Athreya , Dongwoo Lee , Vivek Sant , Corey Arnold , William Speier