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Modeling medical vessel-like anatomy is challenging due to its intricate topology and sensitivity to dataset shifts. Consequently, task-specific models often suffer from topological inconsistencies, including artificial disconnections and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Yaoyu Liu , Minghui Zhang , Xin You , Hanxiao Zhang , Yun Gu

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

Recently segment anything model (SAM) has shown powerful segmentation capability and has drawn great attention in computer vision fields. Massive following works have developed various applications based on the pre-trained SAM and achieved…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Han Shu , Wenshuo Li , Yehui Tang , Yiman Zhang , Yihao Chen , Houqiang Li , Yunhe Wang , Xinghao Chen

The development of radiology foundation models (RFMs) is hindered by a reliance on brute-force scaling. Existing approaches often directly translate methods for natural images, which prioritize scale over precision and hence lead to brittle…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yingtai Li , Shuai Ming , Mingyue Zhao , Haoran Lai , Rongsheng Wang , Rui Zhou , Rundong Wang , Yujia Li , Wei Wei , Shaohua Kevin Zhou

Deploying medical image segmentation models in routine clinical workflows is often constrained by on-premises infrastructure, where computational resources are fixed and cloud-based inference may be restricted by governance and security…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Qizhen Lan , Aaron Choi , Jun Ma , Bo Wang , Zhaogming Zhao , Xiaoqian Jiang , Yu-Chun Hsu

Foundation models have revolutionized computational pathology by achieving remarkable success in high-level diagnostic tasks, yet the critical challenge of low-level image enhancement remains largely unaddressed. Real-world pathology images…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Ziyi Liu , Zhe Xu , Jiabo Ma , Wenqaing Li , Junlin Hou , Fuxiang Huang , Xi Wang , Ronald Cheong Kin Chan , Terence Tsz Wai Wong , Hao Chen

Foundational models have emerged as powerful tools for addressing various tasks in clinical settings. However, their potential development to breast ultrasound analysis remains untapped. In this paper, we present BUSGen, the first…

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma

Current multi-modal image fusion methods typically rely on task-specific models, leading to high training costs and limited scalability. While generative methods provide a unified modeling perspective, they often suffer from slow inference…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Huayi Zhu , Xiu Shu , Youqiang Xiong , Qiao Liu , Rui Chen , Di Yuan , Xiaojun Chang , Zhenyu He

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Large Vision-Language Foundation Models (VLFM), such as CLIP, ALIGN and Florence, are trained on large-scale datasets of image-caption pairs and achieve superior transferability and robustness on downstream tasks, but they are difficult to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Ximeng Sun , Pengchuan Zhang , Peizhao Zhang , Hardik Shah , Kate Saenko , Xide Xia

Recent advances have been made in applying convolutional neural networks to achieve more precise prediction results for medical image segmentation problems. However, the success of existing methods has highly relied on huge computational…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Dian Qin , Jiajun Bu , Zhe Liu , Xin Shen , Sheng Zhou , Jingjun Gu , Zhijua Wang , Lei Wu , Huifen Dai

Masked image modeling (MIM) performs strongly in pre-training large vision Transformers (ViTs). However, small models that are critical for real-world applications cannot or only marginally benefit from this pre-training approach. In this…

Computer Vision and Pattern Recognition · Computer Science 2023-01-04 Sucheng Ren , Fangyun Wei , Zheng Zhang , Han Hu

With access to large-scale, unlabeled medical datasets, researchers are confronted with two questions: Should they attempt to pretrain a custom foundation model on this medical data, or use transfer-learning from an existing generalist…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Jakob Ambsdorf , Asbjørn Munk , Sebastian Llambias , Anders Nymark Christensen , Kamil Mikolaj , Randall Balestriero , Martin Tolsgaard , Aasa Feragen , Mads Nielsen

The integration of AI-assisted biomedical image analysis into clinical practice demands AI-generated findings that are not only accurate but also interpretable to clinicians. However, existing biomedical AI models generally lack the ability…

Despite the promise of foundation models in medical AI, current systems remain limited - they are modality-specific and lack transparent reasoning processes, hindering clinical adoption. To address this gap, we present EVLF-FM, a multimodal…

Cryo-electron microscopy (cryo-EM) is a powerful technique in structural biology and drug discovery, enabling the study of biomolecules at high resolution. Significant advancements by structural biologists using cryo-EM have led to the…

Biomolecules · Quantitative Biology 2024-12-05 Yi Zhou , Yilai Li , Jing Yuan , Quanquan Gu

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Continual learning offers…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed