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Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Artificial Intelligence · Computer Science 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

We study and quantify the problem of forgetting when fine-tuning pre-trained large language models (LLMs) on a downstream task. We find that parameter-efficient fine-tuning (PEFT) strategies, such as Low-Rank Adapters (LoRA), still suffer…

Computation and Language · Computer Science 2024-01-12 Damjan Kalajdzievski

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

Lemmatization of standard languages is concerned with (i) abstracting over morphological differences and (ii) resolving token-lemma ambiguities of inflected words in order to map them to a dictionary headword. In the present paper we aim to…

Computation and Language · Computer Science 2019-03-19 Enrique Manjavacas , Ákos Kádár , Mike Kestemont

Large Language Models (LLMs) like GPT-4o can help automate text classification tasks at low cost and scale. However, there are major concerns about the validity and reliability of LLM outputs. By contrast, human coding is generally more…

Computation and Language · Computer Science 2025-01-17 Conrad Borchers , Danielle R. Thomas , Jionghao Lin , Ralph Abboud , Kenneth R. Koedinger

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Motivation: A perennial challenge for biomedical researchers and clinical practitioners is to stay abreast with the rapid growth of publications and medical notes. Natural language processing (NLP) has emerged as a promising direction for…

Computation and Language · Computer Science 2021-12-16 Robert Tinn , Hao Cheng , Yu Gu , Naoto Usuyama , Xiaodong Liu , Tristan Naumann , Jianfeng Gao , Hoifung Poon

The integration of large language models (LLMs) into automated algorithm design has shown promising potential. A prevalent approach embeds LLMs within search routines to iteratively generate and refine candidate algorithms. However, most…

Machine Learning · Computer Science 2026-05-20 Fei Liu , Rui Zhang , Xi Lin , Zhichao Lu , Qingfu Zhang

Instruction tuning is a pivotal technique for aligning large language models (LLMs) with human intentions, safety constraints, and domain-specific requirements. This survey provides a comprehensive overview of the full pipeline,…

Computation and Language · Computer Science 2025-11-20 Xudong Han , Junjie Yang , Tianyang Wang , Ziqian Bi , Xinyuan Song , Junfeng Hao , Junhao Song

Tools to explore scientific literature are essential for scientists, especially in biomedicine, where about a million new papers are published every year. Many such tools provide users the ability to search for specific entities (e.g.…

Computation and Language · Computer Science 2021-07-05 Sunil Mohan , Rico Angell , Nick Monath , Andrew McCallum

Temporal Logic (TL) can be used to rigorously specify complex high-level specification for systems in many engineering applications. The translation between natural language (NL) and TL has been under-explored due to the lack of dataset and…

Computation and Language · Computer Science 2024-03-25 Yongchao Chen , Rujul Gandhi , Yang Zhang , Chuchu Fan

Generalized Entity Matching (GEM), which aims at judging whether two records represented in different formats refer to the same real-world entity, is an essential task in data management. The prompt tuning paradigm for pre-trained language…

Computation and Language · Computer Science 2024-05-09 Yikuan Xia , Jiazun Chen , Xinchi Li , Jun Gao

The large language model (LLM) is typically integrated into the mainstream optimization protocol. No work has questioned whether maintaining the model integrity is \textit{indispensable} for promising performance. In this work, we introduce…

Computation and Language · Computer Science 2026-03-17 Mingyuan Zhang , Yue Bai , Huan Wang , Yizhou Wang , Qihua Dong , Yitian Zhang , Yun Fu

Large Language Models (LLMs) exhibit a significant "embodiment gap", where their text-based representations fail to align with human sensorimotor experiences. This study systematically investigates whether and how task-specific fine-tuning…

Computation and Language · Computer Science 2026-03-05 Minghua Wu , Javier Conde , Pedro Reviriego , Marc Brysbaert

Pharmaceutical three-dimensional (3D) printing is an advanced fabrication technology with the potential to enable truly personalised dosage forms. Recent studies have integrated artificial intelligence (AI) to accelerate formulation and…

Artificial Intelligence · Computer Science 2026-05-19 Adeshola Okubena , Yusuf Ali Mohammed , Moe Elbadawi

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

Computation and Language · Computer Science 2024-07-12 Masoud Monajatipoor , Jiaxin Yang , Joel Stremmel , Melika Emami , Fazlolah Mohaghegh , Mozhdeh Rouhsedaghat , Kai-Wei Chang

Large language models (LLMs) have shown strong performance on clinical de-identification, the task of identifying sensitive identifiers to protect privacy. However, previous work has not examined their generalizability between formats,…

Computation and Language · Computer Science 2026-02-19 Noopur Zambare , Kiana Aghakasiri , Carissa Lin , Carrie Ye , J. Ross Mitchell , Mohamed Abdalla

Instruction-tuned Large Language Models (LLMs) can perform a wide range of tasks given natural language instructions to do so, but they are sensitive to how such instructions are phrased. This issue is especially concerning in healthcare,…

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler