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This report examines the fine-tuning of Large Language Models (LLMs), integrating theoretical insights with practical applications. It outlines the historical evolution of LLMs from traditional Natural Language Processing (NLP) models to…

Machine Learning · Computer Science 2024-10-31 Venkatesh Balavadhani Parthasarathy , Ahtsham Zafar , Aafaq Khan , Arsalan Shahid

One of the challenges with finetuning pretrained language models (PLMs) is that their tokenizer is optimized for the language(s) it was pretrained on, but brittle when it comes to previously unseen variations in the data. This can for…

Computation and Language · Computer Science 2023-04-21 Verena Blaschke , Hinrich Schütze , Barbara Plank

Recently, large language model (LLM) based artificial intelligence (AI) systems have demonstrated remarkable capabilities in natural language understanding and generation. However, these models face a significant challenge when it comes to…

Large language models have demonstrated remarkable capabilities in biomedical natural language processing, yet their rapid growth in size and computational requirements present a major barrier to adoption in healthcare settings where data…

Computation and Language · Computer Science 2025-09-08 Zaifu Zhan , Shuang Zhou , Min Zeng , Kai Yu , Meijia Song , Xiaoyi Chen , Jun Wang , Yu Hou , Rui Zhang

Large Language Models (LLMs) have become increasingly central to recommendation scenarios due to their remarkable natural language understanding and generation capabilities. Although significant research has explored the use of LLMs for…

Information Retrieval · Computer Science 2025-05-16 Dario Di Palma , Felice Antonio Merra , Maurizio Sfilio , Vito Walter Anelli , Fedelucio Narducci , Tommaso Di Noia

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

In this study, we investigated the ability of the large language model (LLM) to enhance healthcare data interoperability. We leveraged the LLM to convert clinical texts into their corresponding FHIR resources. Our experiments, conducted on…

Computation and Language · Computer Science 2023-10-23 Yikuan Li , Hanyin Wang , Halid Yerebakan , Yoshihisa Shinagawa , Yuan Luo

Cutting edge techniques developed in the general NLP domain are often subsequently applied to the high-value, data-rich biomedical domain. The past few years have seen generative language models (LMs), instruction finetuning, and few-shot…

Computation and Language · Computer Science 2025-07-28 Aviv Brokman , Ramakanth Kavuluru

Large Language Models (LLMs), such as GPT3.5, have exhibited remarkable proficiency in comprehending and generating natural language. On the other hand, medical assistants hold the potential to offer substantial benefits for individuals.…

Computation and Language · Computer Science 2024-04-05 Kai Zhang , Yangyang Kang , Fubang Zhao , Xiaozhong Liu

Artificial intelligence (AI) is widely deployed to solve problems related to marketing attribution and budget optimization. However, AI models can be quite complex, and it can be difficult to understand model workings and insights without…

Computation and Language · Computer Science 2024-04-23 Yilin Gao , Sai Kumar Arava , Yancheng Li , James W. Snyder

Large language models (LLMs) have shown remarkable performance on a variety of NLP tasks, and are being rapidly adopted in a wide range of use cases. It is therefore of vital importance to holistically evaluate the factuality of their…

Computation and Language · Computer Science 2024-04-26 Jiaqing Yuan , Lin Pan , Chung-Wei Hang , Jiang Guo , Jiarong Jiang , Bonan Min , Patrick Ng , Zhiguo Wang

Clinician notes are a rich source of patient information but often contain inconsistencies due to varied writing styles, colloquialisms, abbreviations, medical jargon, grammatical errors, and non-standard formatting. These inconsistencies…

Computation and Language · Computer Science 2025-01-03 Daniel B. Hier , Michael D. Carrithers , Thanh Son Do , Tayo Obafemi-Ajayi

Scientific metadata are often incomplete and noncompliant with community standards, limiting dataset findability, interoperability, and reuse. When reporting guidelines exist, they typically lack machine-actionable representations.…

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

Language models have become increasingly popular in recent years for tasks like information retrieval. As use-cases become oriented toward specific domains, fine-tuning becomes default for standard performance. To fine-tune these models for…

Computation and Language · Computer Science 2023-01-02 Pranjali Awasthi , David Recio-Mitter , Yosuke Kyle Sugi

Large language models (LLMs) have shown great capabilities in various tasks but also exhibited memorization of training data, raising tremendous privacy and copyright concerns. While prior works have studied memorization during…

Artificial Intelligence · Computer Science 2024-02-26 Shenglai Zeng , Yaxin Li , Jie Ren , Yiding Liu , Han Xu , Pengfei He , Yue Xing , Shuaiqiang Wang , Jiliang Tang , Dawei Yin

Large language models (LLMs) such as ChatGPT are fine-tuned on large and diverse instruction-following corpora, and can generalize to new tasks. However, those instruction-tuned LLMs often perform poorly in specialized medical natural…

Computation and Language · Computer Science 2025-03-11 Yujuan Velvin Fu , Giridhar Kaushik Ramachandran , Namu Park , Kevin Lybarger , Fei Xia , Ozlem Uzuner , Meliha Yetisgen

Current approaches to data discovery match keywords between metadata and queries. This matching requires researchers to know the exact wording that other researchers previously used, creating a challenging process that could lead to missing…

Human-Computer Interaction · Computer Science 2025-10-03 Maura E Halstead , Mark A. Green , Caroline Jay , Richard Kingston , David Topping , Alexander Singleton

We investigate the effectiveness of fine-tuning large language models (LLMs) on small medical datasets for text classification and named entity recognition tasks. Using a German cardiology report dataset and the i2b2 Smoking Challenge…

Computation and Language · Computer Science 2025-03-28 Noah Losch , Lucas Plagwitz , Antonius Büscher , Julian Varghese

Research scientists increasingly rely on implementing software to support their research. While previous research has examined the impact of identifier names on program comprehension in traditional programming environments, limited work has…

Software Engineering · Computer Science 2025-07-23 Gunnar Larsen , Carol Wong , Anthony Peruma