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Feedback-rich neural architectures can regenerate earlier representations and inject temporal context, making them a natural setting for strictly local synaptic plasticity. Existing literature raises doubt about whether a minimal,…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Josh Li , Fow-sen Choa

Backpropagation has long been criticized for being biologically implausible due to its reliance on concepts that are not viable in natural learning processes. Two core issues are the weight transport and update locking problems caused by…

Machine Learning · Computer Science 2026-01-14 Katharina Flügel , Daniel Coquelin , Marie Weiel , Charlotte Debus , Achim Streit , Markus Götz

While error backpropagation (BP) has dominated the training of nearly all modern neural networks for a long time, it suffers from several biological plausibility issues such as the symmetric weight requirement and synchronous updates.…

Neurons and Cognition · Quantitative Biology 2023-04-05 Huzi Cheng , Joshua W. Brown

The brain processes information through many layers of neurons. This deep architecture is representationally powerful, but it complicates learning by making it hard to identify the responsible neurons when a mistake is made. In machine…

Neurons and Cognition · Quantitative Biology 2014-11-04 Timothy P. Lillicrap , Daniel Cownden , Douglas B. Tweed , Colin J. Akerman

Training deep neural networks typically relies on backpropagating high dimensional error signals a computationally intensive process with little evidence supporting its implementation in the brain. However, since most tasks involve…

Machine Learning · Computer Science 2026-01-15 Maher Hanut , Jonathan Kadmon

The backpropagation algorithm has experienced remarkable success in training large-scale artificial neural networks; however, its biological plausibility has been strongly criticized, and it remains an open question whether the brain…

Neural and Evolutionary Computing · Computer Science 2026-03-27 Bariscan Bozkurt , Cengiz Pehlevan , Alper T Erdogan

The Backpropagation algorithm relies on the abstraction of using a neural model that gets rid of the notion of time, since the input is mapped instantaneously to the output. In this paper, we claim that this abstraction of ignoring time,…

Machine Learning · Computer Science 2020-06-19 Alessandro Betti , Marco Gori

Supervised learning in deep neural networks is commonly performed using error backpropagation. However, the sequential propagation of errors during the backward pass limits its scalability and applicability to low-powered neuromorphic…

Machine Learning · Computer Science 2023-08-22 Florian Bacho , Dominique Chu

We describe a mechanism for biological learning and adaptation based on two simple principles: (I) Neuronal activity propagates only through the network's strongest synaptic connections (extremal dynamics), and (II) The strengths of active…

Disordered Systems and Neural Networks · Physics 2009-10-31 Per Bak , Dante R Chialvo

With an ever-growing number of parameters defining increasingly complex networks, Deep Learning has led to several breakthroughs surpassing human performance. As a result, data movement for these millions of model parameters causes a…

Neural and Evolutionary Computing · Computer Science 2023-04-12 Christopher Wolters , Brady Taylor , Edward Hanson , Xiaoxuan Yang , Ulf Schlichtmann , Yiran Chen

Error backpropagation is a highly effective mechanism for learning high-quality hierarchical features in deep networks. Updating the features or weights in one layer, however, requires waiting for the propagation of error signals from…

Neural and Evolutionary Computing · Computer Science 2017-11-21 Hesham Mostafa , Vishwajith Ramesh , Gert Cauwenberghs

Neuroscientists have long criticised deep learning algorithms as incompatible with current knowledge of neurobiology. We explore more biologically plausible versions of deep representation learning, focusing here mostly on unsupervised…

Machine Learning · Computer Science 2016-08-10 Yoshua Bengio , Dong-Hyun Lee , Jorg Bornschein , Thomas Mesnard , Zhouhan Lin

The backpropagation algorithm has long been the canonical training method for neural networks. Modern paradigms are implicitly optimized for it, and numerous guidelines exist to ensure its proper use. Recently, synthetic gradients methods…

Machine Learning · Statistics 2019-06-12 Julien Launay , Iacopo Poli , Florent Krzakala

In both machine learning and in computational neuroscience, plasticity in functional neural networks is frequently expressed as gradient descent on a cost. Often, this imposes symmetry constraints that are difficult to reconcile with local…

Neurons and Cognition · Quantitative Biology 2026-04-09 Timo Gierlich , Andreas Baumbach , Akos F. Kungl , Kevin Max , Mihai A. Petrovici

Standard approaches to controlling dynamical systems involve biologically implausible steps such as backpropagation of errors or intermediate model-based system representations. Recent advances in machine learning have shown that…

Statistical Mechanics · Physics 2025-07-11 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

"Forward-only" algorithms, which train neural networks while avoiding a backward pass, have recently gained attention as a way of solving the biologically unrealistic aspects of backpropagation. Here, we first address compelling challenges…

The backpropagation algorithm is often debated for its biological plausibility. However, various learning methods for neural architecture have been proposed in search of more biologically plausible learning. Most of them have tried to solve…

Neural and Evolutionary Computing · Computer Science 2020-11-25 Shashi Kant Gupta

The brain prepares for learning even before interacting with the environment, by refining and optimizing its structures through spontaneous neural activity that resembles random noise. However, the mechanism of such a process has yet to be…

Machine Learning · Computer Science 2025-05-12 Jeonghwan Cheon , Sang Wan Lee , Se-Bum Paik

Backpropagation is a cornerstone algorithm in training neural networks for supervised learning, which uses a gradient descent method to update network weights by minimizing the discrepancy between actual and desired outputs. Despite its…

Supervised learning in artificial neural networks typically relies on backpropagation, where the weights are updated based on the error-function gradients and sequentially propagated from the output layer to the input layer. Although this…

Neural and Evolutionary Computing · Computer Science 2023-06-06 Giorgia Dellaferrera , Gabriel Kreiman