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Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access external knowledge sources, but the effectiveness of RAG relies on the coordination between the retriever and the generator. Since these components are…

Computation and Language · Computer Science 2025-09-24 Junlin Wang , Zehao Wu , Shaowei Lu , Yanlan Li , Xinghao Huang

Retrieval-Augmented Generation (RAG) mitigates hallucination in Large Language Models (LLMs) by incorporating external data, with Knowledge Graphs (KGs) offering crucial information for question answering. Traditional Knowledge Graph…

Computation and Language · Computer Science 2025-09-08 Yushi Sun , Kai Sun , Yifan Ethan Xu , Xiao Yang , Xin Luna Dong , Nan Tang , Lei Chen

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

We propose XRAG, a novel benchmark designed to evaluate the generation abilities of LLMs in cross-lingual Retrieval-Augmented Generation (RAG) settings where the user language does not match the retrieval results. XRAG is constructed from…

Computation and Language · Computer Science 2025-05-16 Wei Liu , Sony Trenous , Leonardo F. R. Ribeiro , Bill Byrne , Felix Hieber

Retrieval-Augmented Generation (RAG) has emerged as a critical technique for enhancing large language model (LLM) capabilities. However, practitioners face significant challenges when making RAG deployment decisions. While existing research…

Software Engineering · Computer Science 2025-07-22 Shengming Zhao , Yuchen Shao , Yuheng Huang , Jiayang Song , Zhijie Wang , Chengcheng Wan , Lei Ma

Large language models (LLMs) often need to incorporate external knowledge to solve theme-specific problems. Retrieval-augmented generation (RAG) has shown its high promise, empowering LLMs to generate more qualified responses with retrieved…

Machine Learning · Computer Science 2025-08-05 Jimeng Shi , Sizhe Zhou , Bowen Jin , Wei Hu , Runchu Tian , Shaowen Wang , Giri Narasimhan , Jiawei Han

Retrieval-Augmented Generation (RAG) plays a crucial role in grounding Large Language Models by leveraging external knowledge, whereas the effectiveness is often compromised by the retrieval of contextually flawed or incomplete information.…

Artificial Intelligence · Computer Science 2025-11-13 Yaoze Zhang , Rong Wu , Pinlong Cai , Xiaoman Wang , Guohang Yan , Song Mao , Ding Wang , Botian Shi

In domains such as materials science, biomedicine, and finance, high-stakes deployment of large language models (LLMs) requires injecting private, domain-specific knowledge that is proprietary, fast-evolving, and under-represented in public…

Computation and Language · Computer Science 2026-04-15 Rongji Li , Jian Xu , Yi Chen , Xueqing Chen , Yisheng Yang , Jiayi Wang , Xingyu Chen , Chunyu Xie , Dawei Leng , Xu-Yao Zhang

Retrieval-Augmented Generation (RAG), which integrates external knowledge into Large Language Models (LLMs), has proven effective in enabling LLMs to produce more accurate and reliable responses. However, it remains a significant challenge…

Computation and Language · Computer Science 2025-02-11 Yan Weng , Fengbin Zhu , Tong Ye , Haoyan Liu , Fuli Feng , Tat-Seng Chua

Large language models (LLMs) have become a disruptive force in the industry, introducing unprecedented capabilities in natural language processing, logical reasoning and so on. However, the challenges of knowledge updates and hallucination…

Machine Learning · Computer Science 2025-04-22 Chunjing Gan , Dan Yang , Binbin Hu , Ziqi Liu , Yue Shen , Zhiqiang Zhang , Jian Wang , Jun Zhou

Proprietary corporate documents contain rich domain-specific knowledge, but their overwhelming volume and disorganized structure make it difficult even for employees to access the right information when needed. For example, in the…

Artificial Intelligence · Computer Science 2025-08-28 Nayoung Choi , Grace Byun , Andrew Chung , Ellie S. Paek , Shinsun Lee , Jinho D. Choi

Retrieval-Augmented Generation (RAG) methods augment the input of Large Language Models (LLMs) with relevant retrieved passages, reducing factual errors in knowledge-intensive tasks. However, contemporary RAG approaches suffer from…

Computation and Language · Computer Science 2024-05-24 Dian Jiao , Li Cai , Jingsheng Huang , Wenqiao Zhang , Siliang Tang , Yueting Zhuang

The integration of external knowledge through Retrieval-Augmented Generation (RAG) has become foundational in enhancing large language models (LLMs) for knowledge-intensive tasks. However, existing RAG paradigms often overlook the cognitive…

Artificial Intelligence · Computer Science 2025-09-24 Yu Wang , Shiwan Zhao , Zhihu Wang , Ming Fan , Xicheng Zhang , Yubo Zhang , Zhengfan Wang , Heyuan Huang , Ting Liu

Retrieval-augmented generation (RAG) has become a cornerstone of contemporary NLP, enhancing large language models (LLMs) by allowing them to access richer factual contexts through in-context retrieval. While effective in monolingual…

Computation and Language · Computer Science 2026-03-31 Leonardo Ranaldi , Barry Haddow , Alexandra Birch

Retrieval-Augmented Generation (RAG) enhances Large Language Model (LLM) output by providing prior knowledge as context to input. This is beneficial for knowledge-intensive and expert reliant tasks, including legal question-answering, which…

Large Language Models (LLMs) have shown remarkable reasoning capabilities, while their practical applications are limited by severe factual hallucinations due to limitations in the timeliness, accuracy, and comprehensiveness of their…

Artificial Intelligence · Computer Science 2025-06-10 Xinyan Guan , Jiali Zeng , Fandong Meng , Chunlei Xin , Yaojie Lu , Hongyu Lin , Xianpei Han , Le Sun , Jie Zhou

Retrieval-augmented generation (RAG) is a paradigm that augments large language models (LLMs) with external knowledge to tackle knowledge-intensive question answering. While several benchmarks evaluate Multimodal LLMs (MLLMs) under…

Computation and Language · Computer Science 2025-08-18 Yin Wu , Quanyu Long , Jing Li , Jianfei Yu , Wenya Wang

Retrieval-augmented generation (RAG) frameworks enable large language models (LLMs) to retrieve relevant information from a knowledge base and incorporate it into the context for generating responses. This mitigates hallucinations and…

Computation and Language · Computer Science 2024-04-09 Pouria Rouzrokh , Shahriar Faghani , Cooper U. Gamble , Moein Shariatnia , Bradley J. Erickson

Retrieval-augmented generation (RAG) methods can enhance the performance of LLMs by incorporating retrieved knowledge chunks into the generation process. In general, the retrieval and generation steps usually have different requirements for…

Information Retrieval · Computer Science 2025-04-16 Peiru Yang , Xintian Li , Zhiyang Hu , Jiapeng Wang , Jinhua Yin , Huili Wang , Lizhi He , Shuai Yang , Shangguang Wang , Yongfeng Huang , Tao Qi
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