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Biomedical question-answering (QA) systems require effective retrieval and generation components to ensure accuracy, efficiency, and scalability. This study systematically examines a Retrieval-Augmented Generation (RAG) system for…

Information Retrieval · Computer Science 2026-01-14 Linus Stuhlmann , Michael Alexander Saxer , Jonathan Fürst

Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…

Computation and Language · Computer Science 2026-03-25 Wenhao Wu , Zhentao Tang , Yafu Li , Shixiong Kai , Mingxuan Yuan , Chunlin Chen , Zhi Wang

Retrieval-augmented generation (RAG) effectively addresses issues of static knowledge and hallucination in large language models. Existing studies mostly focus on question scenarios with clear user intents and concise answers. However, it…

Computation and Language · Computer Science 2025-02-18 Shuting Wang , Xin Yu , Mang Wang , Weipeng Chen , Yutao Zhu , Zhicheng Dou

Retrieval-Augmented Generation (RAG) has emerged as a prominent method for incorporating domain knowledge into Large Language Models (LLMs). While RAG enhances response relevance by incorporating retrieved domain knowledge in the context,…

Computation and Language · Computer Science 2025-03-28 Kushagra Bhushan , Yatin Nandwani , Dinesh Khandelwal , Sonam Gupta , Gaurav Pandey , Dinesh Raghu , Sachindra Joshi

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

In recent years, large language models (LLMs) have made remarkable achievements in various domains. However, the untimeliness and cost of knowledge updates coupled with hallucination issues of LLMs have curtailed their applications in…

Machine Learning · Computer Science 2024-05-31 Chunjing Gan , Dan Yang , Binbin Hu , Hanxiao Zhang , Siyuan Li , Ziqi Liu , Yue Shen , Lin Ju , Zhiqiang Zhang , Jinjie Gu , Lei Liang , Jun Zhou

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Retrieval-Augmented Generation (RAG) has been shown to enhance the factual accuracy of Large Language Models (LLMs), but existing methods often suffer from limited reasoning capabilities in effectively using the retrieved evidence,…

Computation and Language · Computer Science 2024-10-03 Shayekh Bin Islam , Md Asib Rahman , K S M Tozammel Hossain , Enamul Hoque , Shafiq Joty , Md Rizwan Parvez

With the rapid development of large-scale language models, Retrieval-Augmented Generation (RAG) has been widely adopted. However, existing RAG paradigms are inevitably influenced by erroneous retrieval information, thereby reducing the…

Information Retrieval · Computer Science 2024-05-30 Ridong Wu , Shuhong Chen , Xiangbiao Su , Yuankai Zhu , Yifei Liao , Jianming Wu

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

Information Retrieval · Computer Science 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai

Retrieval-Augmented Generation (RAG) has shown substantial promise in improving factual accuracy by grounding model responses with external knowledge relevant to queries. However, most existing approaches are limited to a text-only corpus,…

Computation and Language · Computer Science 2026-05-19 Woongyeong Yeo , Kangsan Kim , Soyeong Jeong , Jinheon Baek , Sung Ju Hwang

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by integrating them with an external knowledge base to improve the answer relevance and accuracy. In real-world scenarios, beyond pure text, a substantial amount of…

Computation and Language · Computer Science 2025-10-07 Jiaru Zou , Dongqi Fu , Sirui Chen , Xinrui He , Zihao Li , Yada Zhu , Jiawei Han , Jingrui He

Retrieval-Augmented Generation (RAG) has emerged as a widely adopted approach for enhancing LLMs in scenarios that demand extensive factual knowledge. However, current RAG evaluations concentrate primarily on correctness, which may not…

Computation and Language · Computer Science 2026-03-23 Vinh Nguyen , Cuong Dang , Jiahao Zhang , Hoa Tran , Minh Tran , Trinh Chau , Thai Le , Lu Cheng , Suhang Wang

Retrieval-Augmented Generation (RAG) integrates non-parametric knowledge into Large Language Models (LLMs), typically from unstructured texts and structured graphs. While recent progress has advanced text-based RAG to multi-turn reasoning…

Computation and Language · Computer Science 2025-12-11 Yucan Guo , Miao Su , Saiping Guan , Zihao Sun , Xiaolong Jin , Jiafeng Guo , Xueqi Cheng

Retrieval-augmented generation (RAG) is a popular technique for using large language models (LLMs) to build customer-support, question-answering solutions. In this paper, we share our team's practical experience building and maintaining…

Information Retrieval · Computer Science 2024-10-18 Sarah Packowski , Inge Halilovic , Jenifer Schlotfeldt , Trish Smith

Large Language Models (LLMs) excel at reasoning and generation but are inherently limited by static pretraining data, resulting in factual inaccuracies and weak adaptability to new information. Retrieval-Augmented Generation (RAG) addresses…

Computation and Language · Computer Science 2025-11-03 Qi Luo , Xiaonan Li , Yuxin Wang , Tingshuo Fan , Yuan Li , Xinchi Chen , Xipeng Qiu

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

Computation and Language · Computer Science 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

As one of the most advanced techniques in AI, Retrieval-Augmented Generation (RAG) can offer reliable and up-to-date external knowledge, providing huge convenience for numerous tasks. Particularly in the era of AI-Generated Content (AIGC),…

Computation and Language · Computer Science 2024-06-18 Wenqi Fan , Yujuan Ding , Liangbo Ning , Shijie Wang , Hengyun Li , Dawei Yin , Tat-Seng Chua , Qing Li

Deploying Large Language Models (LLMs) for healthcare question answering requires robust methods to ensure accuracy and reliability. This work introduces Query-Based Retrieval Augmented Generation (QB-RAG), a framework for enhancing…

Machine Learning · Computer Science 2025-07-31 Eric Yang , Jonathan Amar , Jong Ha Lee , Bhawesh Kumar , Yugang Jia

Although Large Language Models (LLMs) demonstrate significant capabilities, their reliance on parametric knowledge often leads to inaccuracies. Retrieval Augmented Generation (RAG) mitigates this by incorporating external knowledge, but…

Artificial Intelligence · Computer Science 2025-11-04 Hailong Yin , Bin Zhu , Jingjing Chen , Chong-Wah Ngo