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Accurate lesion segmentation in histopathology images is essential for diagnostic interpretation and quantitative analysis, yet it remains challenging due to the limited availability of costly pixel-level annotations. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Hangbei Cheng , Xiaorong Dong , Xueyu Liu , Jianan Zhang , Xuetao Ma , Mingqiang Wei , Liansheng Wang , Junxin Chen , Yongfei Wu

Fully supervised deep learning (DL) models for surgical video segmentation have been shown to struggle with non-adversarial, real-world corruptions of image quality including smoke, bleeding, and low illumination. Foundation models for…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Yiqing Shen , Hao Ding , Xinyuan Shao , Mathias Unberath

Volumetric medical image segmentation is pivotal in enhancing disease diagnosis, treatment planning, and advancing medical research. While existing volumetric foundation models for medical image segmentation, such as SAM-Med3D and SegVol,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Guoan Wang , Jin Ye , Junlong Cheng , Tianbin Li , Zhaolin Chen , Jianfei Cai , Junjun He , Bohan Zhuang

Foundation models like the segment anything model require high-quality manual prompts for medical image segmentation, which is time-consuming and requires expertise. SAM and its variants often fail to segment structures in ultrasound (US)…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Assefa Seyoum Wahd , Banafshe Felfeliyan , Yuyue Zhou , Shrimanti Ghosh , Adam McArthur , Jiechen Zhang , Jacob L. Jaremko , Abhilash Hareendranathan

The development of artificial intelligence models for macular edema (ME) analy-sis always relies on expert-annotated pixel-level image datasets which are expen-sive to collect prospectively. While anomaly-detection-based weakly-supervised…

Image and Video Processing · Electrical Eng. & Systems 2025-08-27 Yuhui Tao , Yizhe Zhang , Qiang Chen

The Segment Anything Model (SAM) is widely used for segmenting a diverse range of objects in natural images from simple user prompts like points or bounding boxes. However, SAM's performance decreases substantially when applied to…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Tristan Piater , Björn Barz , Alexander Freytag

We propose SAMed, a general solution for medical image segmentation. Different from the previous methods, SAMed is built upon the large-scale image segmentation model, Segment Anything Model (SAM), to explore the new research paradigm of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Kaidong Zhang , Dong Liu

Foundation segmentation models such as the Segment Anything Model (SAM) have demonstrated strong generalization across natural images; however, their robustness under clinically realistic medical imaging domain shifts remains insufficiently…

Image and Video Processing · Electrical Eng. & Systems 2026-04-29 Sanghati Basu

Semi-supervised learning has attracted much attention due to its less dependence on acquiring abundant annotations from experts compared to fully supervised methods, which is especially important for medical image segmentation which…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yichi Zhang , Jin Yang , Yuchen Liu , Yuan Cheng , Yuan Qi

Automated segmentation of the left ventricular endocardium in echocardiography videos is a key research area in cardiology. It aims to provide accurate assessment of cardiac structure and function through Ejection Fraction (EF) estimation.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Dongfang Wang , Jian Yang , Yizhe Zhang , Tao Zhou

Semantic segmentation of functional magnetic resonance imaging (fMRI) makes great sense for pathology diagnosis and decision system of medical robots. The multi-channel fMRI provides more information of the pathological features. But the…

Computer Vision and Pattern Recognition · Computer Science 2017-07-12 Lei Tai , Haoyang Ye , Qiong Ye , Ming Liu

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Adapter based fine-tuning has been studied for improving the performance of SAM on downstream tasks. However, there is still a significant performance gap between fine-tuned SAMs and domain-specific models. To reduce the gap, we propose…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Yang Yu , Chen Xu , Kai Wang

Segment Anything Model (SAM) has attracted significant attention due to its impressive zero-shot transfer performance and high versatility for numerous vision applications (like image editing with fine-grained control). Many of such…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Chaoning Zhang , Dongshen Han , Yu Qiao , Jung Uk Kim , Sung-Ho Bae , Seungkyu Lee , Choong Seon Hong

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Yunpeng Xiao , Youpeng Zhao , Ge Yang

The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

The Segment Anything Model (SAM) achieves remarkable promptable segmentation given high-quality prompts which, however, often require good skills to specify. To make SAM robust to casual prompts, this paper presents the first comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Qi Fan , Xin Tao , Lei Ke , Mingqiao Ye , Yuan Zhang , Pengfei Wan , Zhongyuan Wang , Yu-Wing Tai , Chi-Keung Tang

Segmenting objects with complex shapes, such as wires, bicycles, or structural grids, remains a significant challenge for current segmentation models, including the Segment Anything Model (SAM) and its high-quality variant SAM-HQ. These…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Luka Vetoshkin , Dmitry Yudin

Accurate segmentation of 3D medical images is critical for clinical applications like disease assessment and treatment planning. While the Segment Anything Model 2 (SAM2) has shown remarkable success in video object segmentation by…

Image and Video Processing · Electrical Eng. & Systems 2025-10-13 Yeqing Yang , Le Xu , Lixia Tian
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