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Long-term bone healing/adaptation after a dental implant treatment starts with diffusion of mesenchymal stem cells to the fracture callus and their subsequent differentiation. The healing phase is followed by the bone-remodeling phase. In…

Tissues and Organs · Quantitative Biology 2020-11-25 Soroush Irandoust , Sinan Muftu

The purpose of this study is to propose a modified micromorphic continuum model for granular materials based on a micromechanics approach. In this model, Cauchy stress and the couple stress are symmetric conjugated with the symmetric strain…

Geophysics · Physics 2019-07-12 Chenxi Xiu , Xihua Chu

Bone tissue mechanical properties and trabecular microarchitecture are the main factors that determine the biomechanical properties of cancellous bone. Artificial cancellous microstructures, typically described by a reduced number of…

Medical Physics · Physics 2017-07-07 Lucas Colabella , Adrián Cisilino , Guillaume Haiat , Piotr Kowalczyk

The cornea provides the largest refractive power for the human visual system. Its stiffness, along with intraocular pressure (IOP), are linked to several pathologies, including keratoconus and glaucoma. Although mechanical tests can…

We present a fully automated learning-based approach for segmenting knee cartilage in the presence of osteoarthritis (OA). The algorithm employs a hierarchical set of two random forest classifiers. The first is a neighborhood approximation…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Ipek Oguz , Honghai Zhang , Milan Sonka

Ultrasound velocity measurements of magnesium chromite spinel MgCr$_2$O$_4$ reveal elastic anomalies in the paramagnetic phase that are characterized as due to geometrical frustration. The temperature dependence of the tetragonal shear…

Strongly Correlated Electrons · Physics 2012-10-24 Tadataka Watanabe , Shin-Ichi Ishikawa , Haruki Suzuki , Yusuke Kousaka , Keisuke Tomiyasu

A network of semiflexible biopolymers, known as the cytoskeleton, and molecular motors play fundamental mechanical roles in cellular activities. The cytoskeletal response to forces generated by molecular motors is profoundly linked to…

Soft Condensed Matter · Physics 2022-05-25 N. Honda , K. Shiraki , F. van Esterik , S. Inokuchi , H. Ebata , D. Mizuno

Obstructive sleep apnea (OSA) is a complex disease with complex etiology, which requires multidisciplinary cooperation in diagnosis and treatment. Mandibular retrognathia is strongly associated with OSA. Orthodontists can either correct the…

Tissues and Organs · Quantitative Biology 2023-11-03 Menghan Zhang , Yuehua Liu

This paper presents an analytical study about the behavior of arbitrary shaped and sized non-cohesive two-dimensional granular materials. Several mechanical properties and relations are unraveled by connecting micro and macro scales in an…

Geophysics · Physics 2013-02-06 Alex X. Jerves , José E. Andrade

The purpose of this study was to report numerical validation of a 3D finite element model of contracting muscle. The model was based on continuum theory for fibre-reinforced composite materials. Here we simulated contractions for an…

Quantitative Methods · Quantitative Biology 2015-04-03 Hadi Rahemi , Nilima Nigam , James M. Wakeling

Tetrachiral materials are characterized by a cellular microstructure made by a periodic pattern of stiff rings and flexible ligaments. Their mechanical behaviour can be described by a planar lattice of rigid massive bodies and elastic…

Materials Science · Physics 2018-03-05 Marco Lepidi , Andrea Bacigalupo

Soft tissues - such as ligaments and tendons - primarily consist of solid (collagen, predominantly) and liquid phases. Understanding the interaction between such components and how they change under physiological loading sets the basis for…

We consider the estimation of a structural function which models a non-parametric relationship between a response and an endogenous regressor given an instrument in presence of dependence in the data generating process. Assuming an…

Statistics Theory · Mathematics 2016-04-08 Nicolas Asin , Jan Johannes

A stochastic discrete slip approach is proposed to model plastic deformation in submicron domains. The model is applied to the study of submicron pillar ($D~\leq~1\mu m$) compression experiments on tungsten (W), a prototypical metal for…

Materials Science · Physics 2024-04-17 Carlos J. Ruestes , Javier Segurado

Mechanical metamaterials are artifical composites that exhibit a wide range of advanced functionalities such as negative Poisson's ratio, shape-shifting, topological protection, multistability, and enhanced energy dissipation. To date, most…

Soft Condensed Matter · Physics 2020-06-11 Aleksi Bossart , David M. J. Dykstra , Jop van der Laan , Corentin Coulais

This paper presents a framework for modeling failure in quasi-brittle geomaterials under different loading conditions. A micromechanics-based model is proposed in which the field variables are linked to physical mechanisms at the microcrack…

Materials Science · Physics 2021-11-12 Jacinto Ulloa , Jef Wambacq , Roberto Alessi , Esteban Samaniego , Geert Degrande , Stijn François

Bone adapts in response to its mechanical environment. This evolution of bone density is one of the most important mechanisms for developing fracture resistance. A finite element framework for simulating bone adaptation, commonly called…

Computational Engineering, Finance, and Science · Computer Science 2020-01-06 Karol Lewandowski , Łukasz Kaczmarczyk , Ignatios Athanasiadis , John F. Marshall , Chris J. Pearce

In this contribution a magnetoactive elastomer (MAE) of mixed content, i.e., a polymer matrix filled with a mixture of magnetically soft and magnetically hard spherical particles, is considered. The object we focus at is an elementary unit…

Soft Condensed Matter · Physics 2022-10-26 Oleg V. Stolbov , Pedro A. Sánchez , Sofia S. Kantorovich , Yuriy L. Raikher

Collagen is a key structural protein in the human body, which undergoes mineralization during the formation of hard tissues. Earlier studies have described the mechanical behavior of bone at different scales highlighting material features…

Applied Physics · Physics 2021-07-02 Mario Milazzo , Gang Seob Jung , Serena Danti , Markus J. Buehler

Many emerging applications in microscale engineering rely on the fabrication of three-dimensional architectures in inorganic materials. Small-scale additive manufacturing (AM) aspires to provide flexible and facile access to these…