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Molecular property prediction (MPP) is a fundamental but challenging task in the computer-aided drug discovery process. More and more recent works employ different graph-based models for MPP, which have made considerable progress in…

Machine Learning · Computer Science 2023-12-29 Bangyi Zhao , Weixia Xu , Jihong Guan , Shuigeng Zhou

Neural Radiance Fields (NeRF) enables 3D scene reconstruction from several 2D images but incurs high rendering latency via its point-sampling design. 3D Gaussian Splatting (3DGS) improves on NeRF with explicit scene representation and an…

Hardware Architecture · Computer Science 2026-04-07 Haomin Li , Bowen Zhu , Fangxin Liu , Zongwu Wang , Xinran Liang , Li Jiang , Haibing Guan

Deep generative models have been applied with increasing success to the generation of two dimensional molecules as SMILES strings and molecular graphs. In this work we describe for the first time a deep generative model that can generate 3D…

Chemical Physics · Physics 2020-11-24 Tomohide Masuda , Matthew Ragoza , David Ryan Koes

We propose "Generative Fusion Decoding" (GFD), a novel shallow fusion framework designed to integrate large language models (LLMs) into cross-modal text recognition systems for automatic speech recognition (ASR) and optical character…

Computation and Language · Computer Science 2025-06-12 Chan-Jan Hsu , Yi-Chang Chen , Feng-Ting Liao , Pei-Chen Ho , Yu-Hsiang Wang , Po-Chun Hsu , Da-shan Shiu

We introduce a new framework for molecular graph generation with 3D molecular generative models. Our Synthetic Coordinate Embedding (SyCo) framework maps molecular graphs to Euclidean point clouds via synthetic conformer coordinates and…

Machine Learning · Computer Science 2024-06-18 Mohamed Amine Ketata , Nicholas Gao , Johanna Sommer , Tom Wollschläger , Stephan Günnemann

Stochastic process-based molecular graph generators have become the state of the art for template-free single-step retrosynthesis. However, these models are typically trained only on product-reactant pairs, thereby acquiring…

Machine Learning · Computer Science 2026-05-26 Jiahai Huang , Anjie Qiao , Zhen Wang , Defu Lian , Yutong Lu

The crux of molecular property prediction is to generate meaningful representations of the molecules. One promising route is to exploit the molecular graph structure through Graph Neural Networks (GNNs). It is well known that both atoms and…

Quantitative Methods · Quantitative Biology 2020-06-15 Hehuan Ma , Yatao Bian , Yu Rong , Wenbing Huang , Tingyang Xu , Weiyang Xie , Geyan Ye , Junzhou Huang

Molecular property prediction with deep learning has gained much attention over the past years. Owing to the scarcity of labeled molecules, there has been growing interest in self-supervised learning methods that learn generalizable…

Machine Learning · Computer Science 2023-09-04 Peizhen Bai , Xianyuan Liu , Haiping Lu

High-fidelity reconstruction of deformable tissues from endoscopic videos remains challenging due to the limitations of existing methods in capturing subtle color variations and modeling global deformations. While 3D Gaussian Splatting…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Qun Ji , Peng Li , Mingqiang Wei

Disentangled representation is a powerful technique to tackle domain shift problem in medical image analysis in unsupervised domain adaptation setting.However, previous methods only focus on exacting domain-invariant feature and ignore…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Shuai Wang , Rui Li

In this work, we propose a simple transformer-based baseline for multimodal molecular representation learning, integrating three distinct modalities: SMILES strings, 2D graph representations, and 3D conformers of molecules. A key aspect of…

Machine Learning · Computer Science 2024-10-25 Andrei Manolache , Dragos Tantaru , Mathias Niepert

To learn accurate representations of molecules, it is essential to consider both chemical and geometric features. To encode geometric information, many descriptors have been proposed in constrained circumstances for specific types of…

Machine Learning · Computer Science 2023-07-25 Shuo Zhang , Yang Liu , Li Xie , Lei Xie

Complete reconstruction of surgical scenes is crucial for robot-assisted surgery (RAS). Deep depth estimation is promising but existing works struggle with depth discontinuities, resulting in noisy predictions at object boundaries and do…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Xu Wang , Shuai Zhang , Baoru Huang , Danail Stoyanov , Evangelos B. Mazomenos

Late gadolinium enhancement (LGE) cardiac MRI (CMR) is the clinical standard for diagnosis of myocardial scar. 3D isotropic LGE CMR provides improved coverage and resolution compared to 2D imaging. However, image acceleration is required…

Image and Video Processing · Electrical Eng. & Systems 2021-06-02 Burhaneddin Yaman , Chetan Shenoy , Zilin Deng , Steen Moeller , Hossam El-Rewaidy , Reza Nezafat , Mehmet Akçakaya

This paper addresses the challenges of designing mesh convolution neural networks for 3D mesh dense prediction. While deep learning has achieved remarkable success in image dense prediction tasks, directly applying or extending these…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Shi Hezi , Jiang Luo , Zheng Jianmin , Zeng Jun

Deep learning applied to the reconstruction of 3D shapes has seen growing interest. A popular approach to 3D reconstruction and generation in recent years has been the CNN encoder-decoder model usually applied in voxel space. However, this…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Mateusz Michalkiewicz , Eugene Belilovsky , Mahsa Baktashmotlagh , Anders Eriksson

Graph self-supervised learning (GSSL) has demonstrated strong potential for generating expressive graph embeddings without the need for human annotations, making it particularly valuable in domains with high labeling costs such as molecular…

Machine Learning · Computer Science 2026-02-25 Jiele Wu , Haozhe Ma , Zhihan Guo , Thanh Vinh Vo , Tze Yun Leong

Masked Generative Models (MGM)s demonstrate strong capabilities in generating high-fidelity images. However, they need many sampling steps to create high-quality generations, resulting in slow inference speed. In this work, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Pranav Subbaraman , Shufan Li , Siyan Zhao , Aditya Grover

Rapid advancements in machine learning (ML) are transforming materials science by significantly speeding up material property calculations. However, the proliferation of ML approaches has made it challenging for scientists to keep up with…

Machine Learning · Computer Science 2024-07-12 Ali Ramlaoui , Théo Saulus , Basile Terver , Victor Schmidt , David Rolnick , Fragkiskos D. Malliaros , Alexandre Duval

Graph generation techniques are increasingly being adopted for drug discovery. Previous graph generation approaches have utilized relatively small molecular building blocks such as atoms or simple cycles, limiting their effectiveness to…

Machine Learning · Computer Science 2020-04-21 Wengong Jin , Regina Barzilay , Tommi Jaakkola