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In this work we propose a ResNet-based universal method for speckle reduction in optical coherence tomography (OCT) images. The proposed model contains 3 main modules: Convolution-BN-ReLU, Branch and Residual module. Unlike traditional…

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Optical coherence Doppler tomography (ODT) is an emerging blood flow imaging technique. The fundamental unit of ODT is the 1D depth-resolved trace named raw A-scans (or A-line). A 2D ODT image (B-scan) is formed by reconstructing a…

Medical image quality assessment (MIQA) is a vital prerequisite in various medical image analysis applications. Most existing MIQA algorithms are fully supervised that request a large amount of annotated data. However, annotating medical…

Image denoising of low-dose computed tomography (LDCT) is an important problem for clinical diagnosis with reduced radiation exposure. Previous methods are mostly trained with pairs of synthetic or misaligned LDCT and normal-dose CT (NDCT)…

This paper introduces an universal and structure-preserving regularization term, called quantile sparse image (QuaSI) prior. The prior is suitable for denoising images from various medical imaging modalities. We demonstrate its…

Layer segmentation is important to quantitative analysis of retinal optical coherence tomography (OCT). Recently, deep learning based methods have been developed to automate this task and yield remarkable performance. However, due to the…

Anterior segment optical coherence tomography (AS-OCT) is a non-invasive imaging technique that is highly valuable for ophthalmic diagnosis. However, speckles in AS-OCT images can often degrade the image quality and affect clinical…

For optical coherence tomography angiography (OCTA) images, a limited scanning rate leads to a trade-off between field-of-view (FOV) and imaging resolution. Although larger FOV images may reveal more parafoveal vascular lesions, their…

Image harmonization aims to improve the quality of image compositing by matching the "appearance" (\eg, color tone, brightness and contrast) between foreground and background images. However, collecting large-scale annotated datasets for…

To develop a new method to quantify nonperfused retinal capillaries (NPCs) by using co-registered optical coherence tomography (OCT) and OCT angiography (OCTA), and to evaluate NPCs in eyes with age-related macular degeneration (AMD) and…

Clinical measurement of a patient's axial eye length is emerging as a crucial approach to track progression and monitor management of myopia. However, the preferred method for such measurements is swept-source OCT, whose cost prohibits…

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality that allows micron-level resolution to visualize the retinal microvasculature. The retinal vessel segmentation in OCTA images is still an open problem,…

Recently, patch deformation-based methods have demonstrated significant effectiveness in multi-view stereo due to their incorporation of deformable and expandable perception for reconstructing textureless areas. However, these methods…

Retinal Optical Coherence Tomography (OCT), a noninvasive cross-sectional scan of the eye with qualitative 3D visualization of the retinal anatomy is use to study the retinal structure and the presence of pathogens. The advent of the…

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

Optical coherence tomography (OCT) has seen widespread success as an in vivo clinical diagnostic 3D imaging modality, impacting areas including ophthalmology, cardiology, and gastroenterology. Despite its many advantages, such as high…

Self-supervised video denoising aims to remove noise from videos without relying on ground truth data, leveraging the video itself to recover clean frames. Existing methods often rely on simplistic feature stacking or apply optical flow…

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography (SD-OCT) with axial resolution of 5.9 $\mu$m at a center wavelength of 1370 nm. Current supercontinuum-based SD-OCT…