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Related papers: CURE: Confidence-driven Unified Reasoning Ensemble…

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Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

Computation and Language · Computer Science 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

To facilitate robust and trustworthy deployment of large language models (LLMs), it is essential to quantify the reliability of their generations through uncertainty estimation. While recent efforts have made significant advancements by…

Computation and Language · Computer Science 2025-07-22 Rui Li , Jing Long , Muge Qi , Heming Xia , Lei Sha , Peiyi Wang , Zhifang Sui

Demand for mental health support through AI chatbots is surging, though current systems present several limitations, like sycophancy or overvalidation, and reinforcement of maladaptive beliefs. A core obstacle to the creation of better…

Computation and Language · Computer Science 2025-12-08 José Pombal , Maya D'Eon , Nuno M. Guerreiro , Pedro Henrique Martins , António Farinhas , Ricardo Rei

LLMs have demonstrated impressive performance in answering medical questions, such as achieving passing scores on medical licensing examinations. However, medical board exams or general clinical questions do not capture the complexity of…

Computation and Language · Computer Science 2026-02-19 Hanjie Chen , Zhouxiang Fang , Yash Singla , Mark Dredze

Large language models (LLMs) have recently shown strong progress on scientific reasoning, yet two major bottlenecks remain. First, explicit retrieval fragments reasoning, imposing a hidden "tool tax" of extra tokens and steps. Second,…

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Large language models (LLMs) deliver impressive capabilities but incur substantial inference latency and cost, which hinders their deployment in latency-sensitive and resource-constrained scenarios. Cloud-edge-device collaborative inference…

Artificial Intelligence · Computer Science 2026-03-24 Haoyu Qiao , Hao Zhang , Shanwen Mao , Siyao Cheng , Jie Liu

Although contemporary large language models (LMs) demonstrate impressive question-answering capabilities, their answers are typically the product of a single call to the model. This entails an unwelcome degree of opacity and compromises…

Artificial Intelligence · Computer Science 2022-08-31 Antonia Creswell , Murray Shanahan

Large language models (LLMs) often struggle with context fidelity, producing inconsistent answers when responding to questions based on provided information. Existing approaches either rely on expensive supervised fine-tuning to generate…

Computation and Language · Computer Science 2025-09-18 Suyuchen Wang , Jinlin Wang , Xinyu Wang , Shiqi Li , Xiangru Tang , Sirui Hong , Xiao-Wen Chang , Chenglin Wu , Bang Liu

Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

Model merging aggregates Large Language Models (LLMs) finetuned on different tasks into a stronger one. However, parameter conflicts between models leads to performance degradation in averaging. While model routing addresses this issue by…

Machine Learning · Computer Science 2025-02-12 Kunfeng Lai , Zhenheng Tang , Xinglin Pan , Peijie Dong , Xiang Liu , Haolan Chen , Li Shen , Bo Li , Xiaowen Chu

Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

Large language models (LLMs) have achieved strong performance on complex reasoning tasks using techniques such as chain-of-thought and self-consistency. However, ensemble-based approaches, especially self-consistency which relies on…

Artificial Intelligence · Computer Science 2025-12-23 Qinglin Zeng , Jing Yang , Keze Wang

Despite the impressive capabilities of Large Language Models (LLMs), existing Conversational Health Agents (CHAs) remain static and brittle, incapable of adaptive multi-turn reasoning, symptom clarification, or transparent decision-making.…

Computation and Language · Computer Science 2025-07-11 Xinyi Liu , Dachun Sun , Yi R. Fung , Dilek Hakkani-Tür , Tarek Abdelzaher

This study evaluates the capacity of large language models (LLMs) to generate structured clinical consultation templates for electronic consultation. Using 145 expert-crafted templates developed and routinely used by Stanford's eConsult…

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

Computation and Language · Computer Science 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

Large Language Models (LLMs) are widely used in critical fields such as healthcare, education, and finance due to their remarkable proficiency in various language-related tasks. However, LLMs are prone to generating factually incorrect…

Computation and Language · Computer Science 2023-11-27 Muneeswaran I , Shreya Saxena , Siva Prasad , M V Sai Prakash , Advaith Shankar , Varun V , Vishal Vaddina , Saisubramaniam Gopalakrishnan

Large language models (LLMs) are increasingly deployed and democratized on edge devices. To improve the efficiency of on-device deployment, small language models (SLMs) are often adopted due to their efficient decoding latency and reduced…

Computation and Language · Computer Science 2025-02-10 Yu-Neng Chuang , Leisheng Yu , Guanchu Wang , Lizhe Zhang , Zirui Liu , Xuanting Cai , Yang Sui , Vladimir Braverman , Xia Hu

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…