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Related papers: CURE: Confidence-driven Unified Reasoning Ensemble…

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Clinicians often need to retrieve patient-specific information from electronic health records (EHRs), a task that is time-consuming and error-prone. We present a locally deployable Clinical Contextual Question Answering (CCQA) framework…

Computation and Language · Computer Science 2026-03-30 Mikko Saukkoriipi , Nicole Hernandez , Jaakko Sahlsten , Kimmo Kaski , Otso Arponen

Recent advancements in Large Language Models (LLMs) and Large Multi-modal Models (LMMs) have shown potential in various medical applications, such as Intelligent Medical Diagnosis. Although impressive results have been achieved, we find…

With the increasing use of large language models (LLMs) in medical decision-support, it is essential to evaluate not only their final answers but also the reliability of their reasoning. Two key risks are Chain-of-Thought (CoT) faithfulness…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Kaiyuan Ji , Yijin Guo , Zicheng Zhang , Xiangyang Zhu , Yuan Tian , Ning Liu , Guangtao Zhai

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Recent advances in large audio language models (LALMs) have primarily been assessed using a multiple-choice question answering (MCQA) framework. However, subtle changes, such as shifting the order of choices, result in substantially…

Computation and Language · Computer Science 2025-10-07 Fernando López , Santosh Kesiraju , Jordi Luque

Large Language Models (LLMs) demonstrate strong potential across a variety of tasks in communications and networking due to their advanced reasoning capabilities. However, because different LLMs have different model structures and are…

Networking and Internet Architecture · Computer Science 2025-05-07 Haoxiang Luo , Gang Sun , Yinqiu Liu , Dusit Niyato , Hongfang Yu , Mohammed Atiquzzaman , Schahram Dustdar

Large reasoning models excel in domains like mathematics where intermediate reasoning is straightforward to verify, but struggle to self-correct in medicine fields where evaluating intermediate reasoning is cumbersome and expensive. This…

Artificial Intelligence · Computer Science 2026-02-26 Zongxian Yang , Jiayu Qian , Zegao Peng , Haoyu Zhang , Yu-An Huang , KC Tan , Zhi-An Huang

Background: Despite the current ubiquity of Large Language Models (LLMs) across the medical domain, there is a surprising lack of studies which address their reasoning behaviour. We emphasise the importance of understanding reasoning…

Computation and Language · Computer Science 2025-07-29 Shamus Sim , Tyrone Chen

Large Language Models (LLMs), despite their remarkable capabilities, rely on singular, pre-dominant reasoning paradigms, hindering their performance on intricate problems that demand diverse cognitive strategies. To address this, we…

Computation and Language · Computer Science 2025-09-29 Zishan Ahmad , Saisubramaniam Gopalakrishnan

Despite the syntactic fluency of Large Language Models (LLMs), ensuring their logical correctness in high-stakes domains remains a fundamental challenge. We present a neurosymbolic framework that combines LLMs with SMT solvers to produce…

Computation and Language · Computer Science 2026-05-05 Vikash Singh , Darion Cassel , Nathaniel Weir , Nick Feng , Sam Bayless

While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

Machine Learning · Computer Science 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

Large Language Models (LLMs) hold significant promise for mathematics education, yet they often struggle with complex mathematical reasoning. While Retrieval-Augmented Generation (RAG) mitigates these issues by grounding LLMs in external…

Computation and Language · Computer Science 2025-12-02 Shiting Chen , Zijian Zhao , Jinsong Chen

As healthcare increasingly turns to AI for scalable and trustworthy clinical decision support, ensuring reliability in model reasoning remains a critical challenge. Individual large language models (LLMs) are susceptible to hallucinations…

Machine Learning · Computer Science 2025-12-05 Huascar Sanchez , Briland Hitaj , Jules Bergmann , Linda Briesemeister

Concept Bottleneck Models (CBMs) are a prominent framework for interpretable AI that map learned visual features to a set of meaningful concepts for task-specific downstream predictions. Their sequential structure enhances transparency by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Mohamed Harmanani , Bining Long , Zhuoxin Guo , Paul F. R. Wilson , Amirhossein Sabour , Minh Nguyen Nhat To , Gabor Fichtinger , Purang Abolmaesumi , Parvin Mousavi

The miscalibration of Large Reasoning Models (LRMs) undermines their reliability in high-stakes domains, necessitating methods to accurately estimate the confidence of their long-form, multi-step outputs. To address this gap, we introduce…

Computation and Language · Computer Science 2026-01-22 Reza Khanmohammadi , Erfan Miahi , Simerjot Kaur , Ivan Brugere , Charese H. Smiley , Kundan Thind , Mohammad M. Ghassemi

We introduce a novel approach for calibrating uncertainty quantification (UQ) tailored for multi-modal large language models (LLMs). Existing state-of-the-art UQ methods rely on consistency among multiple responses generated by the LLM on…

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

While large language models show promise in medical applications, achieving expert-level clinical reasoning remains challenging due to the need for both accurate answers and transparent reasoning processes. To address this challenge, we…

Machine Learning · Computer Science 2025-09-22 Chi Liu , Derek Li , Yan Shu , Robin Chen , Derek Duan , Teng Fang , Bryan Dai

Recent advances in Transformer-based large language models (LLMs) have led to significant performance improvements across many tasks. These gains come with a drastic increase in the models' size, potentially leading to slow and costly use…

Computation and Language · Computer Science 2022-10-26 Tal Schuster , Adam Fisch , Jai Gupta , Mostafa Dehghani , Dara Bahri , Vinh Q. Tran , Yi Tay , Donald Metzler
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