Related papers: CURE: Confidence-driven Unified Reasoning Ensemble…

Empowered by vast internal knowledge reservoir, the new generation of large language models (LLMs) demonstrate untapped potential to tackle medical tasks. However, there is insufficient effort made towards summoning up a synergic effect…

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Biomedical question answering often requires decisions from retrieved literature whose relevance, quality, and support for candidate answers are uneven. Most retrieval-augmented large language model (LLM) methods feed this literature to the…

Large language models (LLMs) achieve strong reasoning performance through chain-of-thought (CoT) reasoning, yet often generate unnecessarily long reasoning paths that incur high inference cost. Recent self-consistency-based approaches…

While large language models (LLMs) have shown to perform well on monolingual mathematical and commonsense reasoning, they remain unreliable for multilingual medical reasoning applications, hindering their deployment in multilingual…

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Trustworthiness in healthcare question-answering (QA) systems is important for ensuring patient safety, clinical effectiveness, and user confidence. As large language models (LLMs) become increasingly integrated into medical settings, the…

Medical question-answering (QA) is a critical task for evaluating how effectively large language models (LLMs) encode clinical knowledge and assessing their potential applications in medicine. Despite showing promise on multiple-choice…

Multimodal large language models (MLLMs) demonstrate considerable potential in clinical diagnostics, a domain that inherently requires synthesizing complex visual and textual data alongside consulting authoritative medical literature.…

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

The deployment of Large Language Models in Medical Question Answering is severely hampered by ambiguous user queries, a significant safety risk that demonstrably reduces answer accuracy in high-stakes healthcare settings. In this paper, we…

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Large Language Models (LLMs) have shown significant advances in text generation but often lack the reliability needed for autonomous deployment in high-stakes domains like healthcare, law, and finance. Existing approaches rely on external…

Large Language Models (LLMs) have achieved high accuracy on medical question-answer (QA) benchmarks, yet their capacity for flexible clinical reasoning has been debated. Here, we asked whether advances in reasoning LLMs improve their…

We introduce a new approach in which several advanced large language models-specifically GPT-4-0125-preview, Meta-LLAMA-3-70B-Instruct, Claude-3-Opus, and Gemini-1.5-Flash-collaborate to both produce and answer intricate, doctoral-level…

Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

Large language models (LLMs) achieve strong average performance yet remain unreliable at the instance level, with frequent hallucinations, brittle failures, and poorly calibrated confidence. We study reliability through the lens of…

Medical Question-Answering (QA) encompasses a broad spectrum of tasks, including multiple choice questions (MCQ), open-ended text generation, and complex computational reasoning. Despite this variety, a unified framework for delivering…

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that…