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Quantifying the uncertainty of predictions is a core problem in modern statistics. Methods for predictive inference have been developed under a variety of assumptions, often -- for instance, in standard conformal prediction -- relying on…

Methodology · Statistics 2024-09-13 Edgar Dobriban , Mengxin Yu

Prediction algorithms, such as deep neural networks (DNNs), are used in many domain sciences to directly estimate internal parameters of interest in simulator-based models, especially in settings where the observations include images or…

Machine Learning · Statistics 2023-11-14 Luca Masserano , Tommaso Dorigo , Rafael Izbicki , Mikael Kuusela , Ann B. Lee

Simulation-based inference (SBI) is transforming experimental sciences by enabling parameter estimation in complex non-linear models from simulated data. A persistent challenge, however, is model misspecification: simulators are only…

Machine Learning · Statistics 2025-10-20 Pierre-Louis Ruhlmann , Pedro L. C. Rodrigues , Michael Arbel , Florence Forbes

Recursive Bayesian inference (RBI) provides optimal Bayesian latent variable estimates in real-time settings with streaming noisy observations. Active RBI attempts to effectively select queries that lead to more informative observations to…

Machine Learning · Computer Science 2021-03-11 Yeganeh M. Marghi , Aziz Kocanaogullari , Murat Akcakaya , Deniz Erdogmus

Statistical shape modeling (SSM) enables population-based quantitative analysis of anatomical shapes, informing clinical diagnosis. Deep learning approaches predict correspondence-based SSM directly from unsegmented 3D images but require…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Jadie Adams , Shireen Elhabian

NeuroAI is an emerging field at the intersection of neuroscience and artificial intelligence, where insights from brain function guide the design of intelligent systems. A central area within this field is synthetic biological intelligence…

Neurons and Cognition · Quantitative Biology 2025-10-10 Dhruvik Patel , Md Sayed Tanveer , Jesus Gonzalez-Ferrer , Alon Loeffler , Brett J. Kagan , Mohammed A. Mostajo-Radji , Ge Wang

The human brain utilizes spikes for information transmission and dynamically reorganizes its network structure to boost energy efficiency and cognitive capabilities throughout its lifespan. Drawing inspiration from this spike-based…

Human-Computer Interaction · Computer Science 2025-02-20 Jiangrong Shen , Qi Xu , Gang Pan , Badong Chen

Bayesian optimal experimental design (BOED) seeks to maximize the expected information gain (EIG) of experiments. This requires a likelihood estimate, which in many settings is intractable. Simulation-based inference (SBI) provides powerful…

Machine Learning · Computer Science 2026-02-09 Samuel Klein , Willie Neiswanger , Daniel Ratner , Michael Kagan , Sean Gasiorowski

Neural networks are being extensively used for modelling data, especially in the case where no likelihood can be formulated. Although in the case of X-ray spectral fitting, the likelihood is known, we aim to investigate the neural networks…

Instrumentation and Methods for Astrophysics · Physics 2024-02-22 Didier Barret , Simon Dupourqué

Humans often juggle multiple, sometimes conflicting objectives and shift their priorities as circumstances change, rather than following a fixed objective function. In contrast, most computational decision-making and multi-objective RL…

Artificial Intelligence · Computer Science 2026-03-25 Xianwei Cao , Dou Quan , Zhenliang Zhang , Shuang Wang

Physics-informed deep learning approaches have been developed to solve forward and inverse stochastic differential equation (SDE) problems with high-dimensional stochastic space. However, the existing deep learning models have difficulties…

Computational Physics · Physics 2026-03-05 Shaoqian Zhou , Wen You , Ling Guo , Xuhui Meng

Spatiotemporal learning is challenging due to the intricate interplay between spatial and temporal dependencies, the high dimensionality of the data, and scalability constraints. These challenges are further amplified in scientific domains,…

Machine Learning · Computer Science 2025-04-17 David Keetae Park , Xihaier Luo , Guang Zhao , Seungjun Lee , Miruna Oprescu , Shinjae Yoo

We present a new distribution-free conformal prediction algorithm for sequential data (e.g., time series), called the \textit{sequential predictive conformal inference} (\texttt{SPCI}). We specifically account for the nature that time…

Machine Learning · Statistics 2023-05-31 Chen Xu , Yao Xie

Seismic full-waveform inversion (FWI), which uses iterative methods to estimate high-resolution subsurface models from seismograms, is a powerful imaging technique in exploration geophysics. In recent years, the computational cost of FWI…

Geophysics · Physics 2023-11-28 Shihang Feng , Youzuo Lin , Brendt Wohlberg

We introduce \textit{OneFlowSBI}, a unified framework for simulation-based inference that learns a single flow-matching generative model over the joint distribution of parameters and observations. Leveraging a query-aware masking…

I propose a novel framework that integrates stochastic differential equations (SDEs) with deep generative models to improve uncertainty quantification in machine learning applications involving structured and temporal data. This approach,…

Machine Learning · Statistics 2026-01-09 James Rice

We develop the framework of Linear Simulation-based Inference (LSBI), an application of simulation-based inference where the likelihood is approximated by a Gaussian linear function of its parameters. We obtain analytical expressions for…

Instrumentation and Methods for Astrophysics · Physics 2025-01-08 Nicolas Mediato-Diaz , Will Handley

Simulation Based Inference (SBI) is shown to yield more accurate resonance parameter estimates than traditional chi-squared minimization in certain cases of model misspecification, demonstrated through a case study of pi-pi scattering and…

High Energy Physics - Phenomenology · Physics 2025-07-28 Daniel Sadasivan , Isaac Cordero , Andrew Graham , Cecilia Marsh , Daniel Kupcho , Melana Mourad , Maxim Mai

Flow and diffusion generative models have established themselves as widely adopted density estimators for simulation-based inference (SBI), extending naturally from neural posterior estimation to likelihood and joint density estimation.…

Machine Learning · Computer Science 2026-05-28 Aurelio Amerio

Statistical inference in physics is often based on samples from a generator (sometimes referred to as a ``forward model") that emulate experimental data and depend on parameters of the underlying theory. Modern machine learning has…

High Energy Physics - Phenomenology · Physics 2025-06-03 Chi Lung Cheng , Ranit Das , Runze Li , Radha Mastandrea , Vinicius Mikuni , Benjamin Nachman , David Shih , Gup Singh
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