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Reconstructing a map of neuronal connectivity is a critical challenge in contemporary neuroscience. Recent advances in high-throughput serial section electron microscopy (EM) have produced massive 3D image volumes of nanoscale brain tissue…
Background: Apparent Diffusion Coefficient (ADC) values and Total Diffusion Volume (TDV) from Whole-body diffusion-weighted MRI (WB-DWI) are recognized cancer imaging biomarkers. However, manual disease delineation for ADC and TDV…
The segmentation of the retinal vasculature from eye fundus images represents one of the most fundamental tasks in retinal image analysis. Over recent years, increasingly complex approaches based on sophisticated Convolutional Neural…
Segmentation of abdominal computed tomography(CT) provides spatial context, morphological properties, and a framework for tissue-specific radiomics to guide quantitative Radiological assessment. A 2015 MICCAI challenge spurred substantial…
Shape graphs are complex geometrical structures commonly found in biological and anatomical systems. A shape graph is a collection of nodes, some connected by curvilinear edges with arbitrary shapes. Their high complexity stems from the…
Cardiac structure segmentation plays an important role in medical analysis procedures. Images' blurred boundaries issue always limits the segmentation performance. To address this difficult problem, we presented a novel network structure…
Labelling tissue components in histology whole slide images (WSIs) is prohibitively labour-intensive: a single slide may contain tens of thousands of structures--cells, nuclei, and other morphologically distinct objects--each requiring…
Brain surface analysis is essential to neuroscience, however, the complex geometry of the brain cortex hinders computational methods for this task. The difficulty arises from a discrepancy between 3D imaging data, which is represented in…
Gliomas are brain tumors composed of different highly heterogeneous histological subregions. Image analysis techniques to identify relevant tumor substructures have high potential for improving patient diagnosis, treatment and prognosis.…
To develop and validate a fully automated, deep-learning pipeline for measuring glenoid bone loss on 3D CT scans using linear-based, en-face view, and best-circle method. Shoulder CT scans of 81 patients were retrospectively collected…
In the brain, the structure of a network of neurons defines how these neurons implement the computations that underlie the mind and the behavior of animals and humans. Provided that we can describe the network of neurons as a graph, we can…
Segmentation of the coronary artery is an important task for the quantitative analysis of coronary computed tomography angiography (CCTA) images and is being stimulated by the field of deep learning. However, the complex structures with…
Computer aided diagnosis (CAD) systems are designed to assist clinicians in various tasks, including highlighting abnormal regions in a medical image. A common approach consists in training a voxel-level binary classifier on a set of…
When the blood supply to the brain is obstructed by a clot, oxygen delivery to brain tissues becomes insufficient, leading to cellular necrosis. In healthcare settings, accurately identifying and delineating ischemic lesion boundaries is…
Accurate and efficient registration of whole slide images (WSIs) is essential for high-resolution, nuclei-level analysis in multi-stained tissue slides. We propose a novel coarse-to-fine framework CORE for accurate nuclei-level registration…
Magnetic resonance (MR) imaging is essential for evaluating central nervous system (CNS) tumors, guiding surgical planning, treatment decisions, and assessing postoperative outcomes and complication risks. While recent work has advanced…
The skeleton of a digital image is a compact representation of its topology, geometry, and scale. It has utility in many computer vision applications, such as image description, segmentation, and registration. However, skeletonization has…
Scoliosis is a congenital disease in which the spine is deformed from its normal shape. Measurement of scoliosis requires labeling and identification of vertebrae in the spine. Spine radiographs are the most cost-effective and accessible…
Due to imaging artifacts and low signal-to-noise ratio in ultrasound images, automatic bone surface segmentation networks often produce fragmented predictions that can hinder the success of ultrasound-guided computer-assisted surgical…
Carotid artery vessel wall thickness measurement is an essential step in the monitoring of patients with atherosclerosis. This requires accurate segmentation of the vessel wall, i.e., the region between an artery's lumen and outer wall, in…