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In this research, we introduce an innovative three-network architecture that comprises an encoder-decoder framework with an attention mechanism. The architecture comprises a 1st-order-pre-trainer, a 2nd-order-improver, and a discriminator…

Computational Physics · Physics 2023-11-28 Jian-Nan Chen , Jun-Jie Zhang

This paper considers flow problems in multiscale heterogeneous porous media. The multiscale nature of the modeled process significantly complicates numerical simulations due to the need to compute huge and ill-conditioned sparse matrices,…

Numerical Analysis · Mathematics 2024-10-16 Djulustan Nikiforov , Leonardo A. Poveda , Dmitry Ammosov , Yesy Sarmiento , Juan Galvis

Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

Soft Condensed Matter · Physics 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

In this paper, a Feature-preserving Particle Generation (FPPG) method for arbitrary complex geometry is proposed. Instead of basing on implicit geometries, such as level-set, FPPG employs an explicit geometric representation for the…

Computational Physics · Physics 2025-01-07 Xingyue Yang , Zhenxiang Nie , Yuxin Dai , Zhe Ji

One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks - and how can…

Computational Engineering, Finance, and Science · Computer Science 2015-10-20 Dagmar Iber , Zahra Karimaddini , Erkan Ünal

Particle accelerator modeling is an important field of research and development, essential to investigating, designing and operating some of the most complex scientific devices ever built. Kinetic simulations of relativistic, charged…

Accelerator Physics · Physics 2024-05-02 Ryan T. Sandberg , Remi Lehe , Chad E. Mitchell , Marco Garten , Andrew Myers , Ji Qiang , Jean-Luc Vay , Axel Huebl

Angiogenesis, the development of new vasculature, is a critical process in the growth of new tumors. Driven by a goal to understand this aspect of cancer proliferation, I develop a discrete computationally optimized mathematical model of…

Cell Behavior · Quantitative Biology 2016-02-11 Dibya Jyoti Ghosh

Lightsheet microscopy is a powerful 3-D imaging technique that addresses limitations of traditional optical and confocal microscopy but suffers from a low penetration depth and reduced image quality at greater depths. Multiview lightsheet…

Image and Video Processing · Electrical Eng. & Systems 2025-03-21 Marek Wodzinski , Henning Müller

We present a computational framework for modeling large-scale particle-laden flows in complex domains with the goal of enabling simulations in medical-image derived patient specific geometries. The framework is based on a volume-filtered…

Fluid Dynamics · Physics 2023-11-28 Abhilash Reddy Malipeddi , C. Alberto Figueroa , Jesse Capecelatro

Among the approaches in three-dimensional (3D) single molecule localization microscopy, there are several point spread function (PSF) engineering approaches, in which depth information of molecules is encoded in 2D images. Usually,the…

Optics · Physics 2024-07-11 Hanzhe Wu , Danni Chen , YiHong Jiand Gan Xiang , Heng Li , Bin Yu , JunLe Qu

The Keller-Segel (KS) chemotaxis system is used to describe the overall behavior of a collection of cells under the influence of chemotaxis. However, solving the KS chemotaxis system and generating its aggregation patterns remain…

Numerical Analysis · Mathematics 2025-10-17 Yani Feng , Michael K. Ng , Zhiwen Zhang

In this paper, we propose a novel $hr$-adaptive finite element method, enhanced by neural networks, for parabolic equations. The main challenge of the conventional $h$-adaptive finite element method is interpolating the finite element…

Numerical Analysis · Mathematics 2025-10-22 Jiaxiong Hao , Yunqing Huang , Nianyu Yi , Peimeng Yin

Neural network quantum states (NQS) have emerged as a powerful and flexible framework for addressing quantum many-body problems. While successful for model Hamiltonians, their application to molecular systems remains challenging for several…

Chemical Physics · Physics 2025-07-28 Zibo Wu , Bohan Zhang , Wei-Hai Fang , Zhendong Li

Photoplethysmography (PPG) is a widely used non-invasive physiological sensing technique, suitable for various clinical applications. Such clinical applications are increasingly supported by machine learning methods, raising the question of…

Numerical simulation is indispensable in industrial design processes. It can replace expensive experiments and even reduce the need for prototypes. While products designed with the aid of numerical simulation undergo continuous improvement,…

Numerical Analysis · Mathematics 2020-06-04 Henning Wessels , Christian Weißenfels , Peter Wriggers

Recently, a fully implicit, energy- and charge-conserving particle-in-cell method has been proposed for multi-scale, full-f kinetic simulations [G. Chen, et al., J. Comput. Phys. 230,18 (2011)]. The method employs a Jacobian-free…

Plasma Physics · Physics 2015-06-03 Guangye Chen , Luis Chacón , Daniel C. Barnes

Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…

Traditional methods for biological shape inference, such as deep learning (DL) and active contour models, face important limitations in 3D. DL approaches require large annotated datasets, which are often impractical to obtain, while active…

Biological Physics · Physics 2025-08-04 Sacha Ichbiah , Anshuman Sinha , Fabrice Delbary , Hervé Turlier

High-fidelity modeling of plasma-based acceleration (PBA) requires the use of 3D fully nonlinear and kinetic descriptions based on the particle-in-cell (PIC) method. Three-dimensional PIC algorithms based on the quasi-static approximation…

Plasma Physics · Physics 2022-09-28 Fei Li , Weiming An , Frank S. Tsung , Viktor K. Decyk , Warren B. Mori

Particle-stabilised emulsions are a cornerstone of soft matter science due to their broad application and fundamental relevance. Computer simulations provide key insights into the formation and behaviour of these emulsions, yet current…

Soft Condensed Matter · Physics 2026-02-19 Elisabeth C. Eij , Joost de Graaf , Martin F. Haase , Jesse M. Steenhoff