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We study epidemic processes using a metapopulation approach on the line featuring random transport rates between arbitrarily distant sites. An average transport network is found using a recently developed variant of the effective medium…

Physics and Society · Physics 2018-10-17 Flavio Iannelli , Igor M. Sokolov , Felix Thiel

In order to survive, reproduce and (in multicellular organisms) differentiate, cells must control the concentrations of the myriad different proteins that are encoded in the genome. The precision of this control is limited by the inevitable…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Aleksandra M. Walczak , William Bialek

Cells offer numerous inspiring examples where proteins and membranes combine to form complex structures that are key to intracellular compartmentalization, cargo transport, and specialization of cell morphology. Despite this wealth of…

The Ribosome Flow Model (RFM) describes the unidirectional movement of interacting particles along a one-dimensional chain of sites. As a site becomes fuller, the effective entry rate into this site decreases. The RFM has been used to model…

Networking and Internet Architecture · Computer Science 2015-08-26 Yoram Zarai , Oz Mendel , Michael Margaliot

In biological cells and novel diagnostic devices biochemical receptors need to be sensitive to extremely small concentration changes of signaling molecules. The accuracy of such molecular signaling is ultimately limited by the counting…

Subcellular Processes · Quantitative Biology 2023-04-06 Aljaz Godec , Ralf Metzler

Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this…

Optics · Physics 2007-05-23 Laurent Cognet , Laurent Groc , Brahim Lounis , Daniel Choquet

In recent years, extracellular vesicles such have become promising carriers as the next-generation drug delivery platforms. Effective loading of exogenous cargos without compromising the extracellular vesicle membrane is a major challenge.…

Biomolecules · Quantitative Biology 2023-04-14 Khayrul Islam , Meghdad Razizadeh , Yaling Liu

Diffusion of transported particles in the intracellular medium is described by means of a generalized diffusion equation containing forces due to the cytoskeleton network and to the protein motors. We find that the enhanced diffusion…

Soft Condensed Matter · Physics 2009-02-05 I. Santamaria-Holek , M. H. Vainstein , J. M. Rubi , F. A. Oliveira

Flux of rigid or soft particles (such as drops, vesicles, red blood cells, etc.) in a channel is a complex function of particle concentration, which depends on the details of induced dissipation and suspension structure due to hydrodynamic…

Opals are structures composed of the closed packing of spheres in the size range of nano-to-micro meter. They are sintered to create small necks at the points of contact. We have solved the diffusion problem in such structures. The relation…

Materials Science · Physics 2009-10-31 J. O. Sofo , G. D. Mahan

Endocytosis is an essential biological process for the trafficking of macromolecules (cargo) and membrane proteins in cells. In yeast cells, this involves the invagination of a tubular structure on the membrane and the formation of…

Soft Condensed Matter · Physics 2022-11-18 Ke Xiao , Chen-Xu Wu , Rui Ma

Random networks offer fertile ground for achieving complexity and criticality, both crucial for an unconventional computing paradigm inspired by biological brains' features. In this work, we focus on characterizing and modeling different…

Materials Science · Physics 2025-01-28 J. I. Diaz Schneider , C. P. Quinteros , P. E. Levy , E. D. Martínez

Passive particle transport through narrow channels is well studied, while for active particle systems, it is not well understood. Here, we demonstrate the active control of the transport through a nanopore via mean-field analysis and…

Soft Condensed Matter · Physics 2021-07-21 Cheng Lian , Wei Zhong

Nucleon-nucleon (NN) cross sections are evaluated in neutron-rich matter using a scaling model according to nucleon effective masses. It is found that the in-medium NN cross sections are not only reduced but also have a different isospin…

Nuclear Theory · Physics 2008-11-26 Bao-An Li , Lie-Wen Chen

Magnetic reconnection is a fundamental plasma process that alters the magnetic field topology and releases magnetic energy. Most numerical simulations and spacecraft observations assume a two-dimensional diffusion region, with the electron…

Space Physics · Physics 2026-04-24 Xinmin Li , Chuanfei Dong , Hantao Ji , Chi Zhang , Liang Wang , Barbara Giles , Hongyang Zhou , Rui Chen , Yi Qi

Protein aggregation on the plasma membrane (PM) is of critical importance to many cellular processes such as cell adhesion, endocytosis, fibrillar conformation, and vesicle transport. Lateral diffusion of protein aggregates or clusters on…

Subcellular Processes · Quantitative Biology 2019-08-15 L. M. Stolerman , M. Getz , S. G. Llewellyn Smith , M. Holst , P. Rangamani

This paper proposes an effective phase diffusion method to analyze chemical exchange in nuclear magnetic resonance (NMR). The chemical exchange involves spin jumps around different sites where the spin angular frequencies vary, which leads…

Chemical Physics · Physics 2023-07-19 Guoxing Lin

The binding of proteins onto DNA contributes to the shaping and packaging of genome as well as to the expression of specific genetic messages. With a view to understanding the interplay between the presence of proteins and the deformation…

Biological Physics · Physics 2014-05-30 Nicolas Clauvelin , Wilma K. Olson

Molecular communication between biological entities is a new paradigm in communications. Recently, we studied molecular communication between two nodes formed from synthetic bacteria. Due to high randomness in behavior of bacteria, we used…

Emerging Technologies · Computer Science 2014-10-07 Arash Einolghozati , Mohsen Sardari , Faramarz Fekri

The recent improvements in cryo-electron microscopy (cryo-EM) in the past few years are now allowing to observe molecular complexes at atomic resolution. As a consequence, numerous structures derived from cryo-EM are now available in the…

Biomolecules · Quantitative Biology 2020-05-04 Mikael Trellet , Gydo van Zundert , Alexandre M. J. J. Bonvin