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Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

With the proliferation of large language models (LLMs) in the medical domain, there is increasing demand for improved evaluation techniques to assess their capabilities. However, traditional metrics like F1 and ROUGE, which rely on token…

Computation and Language · Computer Science 2025-05-20 Xiechi Zhang , Zetian Ouyang , Linlin Wang , Gerard de Melo , Zhu Cao , Xiaoling Wang , Ya Zhang , Yanfeng Wang , Liang He

Large language models (LLMs) show increasing promise in medical applications, but their ability to detect and correct errors in clinical texts -- a prerequisite for safe deployment -- remains under-evaluated, particularly beyond English. We…

Computation and Language · Computer Science 2025-11-04 Naoto Iwase , Hiroki Okuyama , Junichiro Iwasawa

Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…

Artificial Intelligence · Computer Science 2025-06-26 Weijieying Ren , Tianxiang Zhao , Lei Wang , Tianchun Wang , Vasant Honavar

Large Language Models (LLMs) have achieved rapid progress in Chinese language understanding, yet accurately evaluating their capabilities remains challenged by benchmark saturation and prohibitive computational costs. While static…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Rui Fang , Jian Li , Wei Chen , Bin Hu , Ying-Cong Chen , Xin Tang , Liang Diao

Large language models (LLMs) have achieved remarkable performance in various evaluation benchmarks. However, concerns are raised about potential data contamination in their considerable volume of training corpus. Moreover, the static nature…

Artificial Intelligence · Computer Science 2024-03-15 Kaijie Zhu , Jiaao Chen , Jindong Wang , Neil Zhenqiang Gong , Diyi Yang , Xing Xie

Large Language Models (LLMs) are increasingly applied to medicine, yet their adoption is limited by concerns over reliability and safety. Existing evaluations either test factual medical knowledge in isolation or assess patient-level…

Computation and Language · Computer Science 2026-05-08 Zhan Qu , Michael Färber

Ensuring the safety and reliability of large language models (LLMs) in clinical practice is critical to prevent patient harm. However, LLMs are advancing so rapidly that static benchmarks quickly become obsolete or prone to overfitting,…

Evaluating large language models (LLMs) today rests on fixed benchmarks that apply the same set of items to any model, producing ceiling and floor effects that mask capability gaps. We argue that the most informative evaluation signal lies…

Artificial Intelligence · Computer Science 2026-05-27 Haoxiang Wang , Da Yu , Huishuai Zhang

Automatically generated radiology reports often receive high scores from existing evaluation metrics but fail to earn clinicians' trust. This gap reveals fundamental flaws in how current metrics assess the quality of generated reports. We…

Computation and Language · Computer Science 2025-10-02 Ruochen Li , Jun Li , Bailiang Jian , Kun Yuan , Youxiang Zhu

Interactive medical consultation requires an agent to proactively elicit missing clinical evidence under uncertainty. Yet existing evaluations largely remain static or outcome-centric, neglecting the evidence-gathering process. In this…

Computation and Language · Computer Science 2026-01-28 Zhuohan Long , Zhijie Bao , Zhongyu Wei

Existing evaluation of Large Language Models (LLMs) on static benchmarks is vulnerable to data contamination and leaderboard overfitting, critical issues that obscure true model capabilities. To address this, we introduce LLMEval-Fair, a…

Large language models (LLMs) have emerged as powerful tools for analyzing complex datasets. Recent studies demonstrate their potential to generate useful, personalized responses when provided with patient-specific health information that…

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

Recent advances in large language models (LLMs) have demonstrated impressive reasoning capacities that mirror human-like thinking. However, whether LLMs possess genuine fluid intelligence (i.e., the ability to reason abstractly and…

Artificial Intelligence · Computer Science 2025-09-30 Yue Yang , MingKang Chen , Qihua Liu , Mengkang Hu , Qiguang Chen , Gengrui Zhang , Shuyue Hu , Guangtao Zhai , Yu Qiao , Yu Wang , Wenqi Shao , Ping Luo

This paper presents a benchmark self-evolving framework to dynamically evaluate rapidly advancing Large Language Models (LLMs), aiming for a more accurate assessment of their capabilities and limitations. We utilize a multi-agent system to…

Computation and Language · Computer Science 2024-02-20 Siyuan Wang , Zhuohan Long , Zhihao Fan , Zhongyu Wei , Xuanjing Huang

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

Artificial Intelligence · Computer Science 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

Language models (LMs) are increasingly being integrated into a wide range of applications, yet the modern evaluation paradigm does not sufficiently reflect how they are actually being used. Current evaluations rely on benchmarks that often…

Computation and Language · Computer Science 2025-04-15 Aryan Shrivastava , Paula Akemi Aoyagui

Multimodal large language models (MLLMs) have shown great potential in medical applications, yet existing benchmarks inadequately capture real-world clinical complexity. We introduce MEDSYN, a multilingual, multimodal benchmark of highly…

Computation and Language · Computer Science 2026-04-20 Boqi Chen , Xudong Liu , Jiachuan Peng , Marianne Frey-Marti , Bang Zheng , Kyle Lam , Lin Li , Jianing Qiu