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Medical large language models (LLMs) research often makes bold claims, from encoding clinical knowledge to reasoning like a physician. These claims are usually backed by evaluation on competitive benchmarks; a tradition inherited from…
Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…
Critical appraisal of scientific literature is an essential skill in the biomedical field. While large language models (LLMs) can offer promising support in this task, their reliability remains limited, particularly for critical reasoning…
Despite impressive performance on standard benchmarks, multimodal large language models (MLLMs) face critical challenges in real-world clinical environments where medical images inevitably suffer various quality degradations. Existing…
Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…
Multimodal large language models (LLMs) are increasingly used to generate dermatology diagnostic narratives directly from images. However, reliable evaluation remains the primary bottleneck for responsible clinical deployment. We introduce…
Multimodal Large Language Models (MLLMs) increasingly support dynamic image resolutions. However, current evaluation paradigms primarily assess semantic performance, overlooking the critical question of resolution robustness - whether…
While Large Language Models (LLMs) achieve superhuman performance on standardized medical licensing exams, these static benchmarks have become saturated and increasingly disconnected from the functional requirements of clinical workflows.…
General Multimodal Large Language Models (MLLMs) often underperform in capturing domain-specific nuances in medical diagnosis, trailing behind fully supervised baselines. Although fine-tuning provides a remedy, the high costs of expert…
Medical large language models (LLMs) achieve impressive performance on standardized benchmarks, yet these evaluations fail to capture the complexity of real clinical encounters where patients exhibit memory gaps, limited health literacy,…
There is growing interest in using machine learning (ML) to support clinical diagnosis, but most approaches rely on static, fully observed datasets and fail to reflect the sequential, resource-aware reasoning clinicians use in practice.…
The emergence of large language models (LLMs) has significantly influenced numerous fields, including healthcare, by enhancing the capabilities of automated systems to process and generate human-like text. However, despite their…
Current medical AI systems often fail to replicate real-world clinical reasoning, as they are predominantly trained and evaluated on static text and question-answer tasks. These tuning methods and benchmarks overlook critical aspects like…
Large language models (LLMs) hold promise in clinical decision support but face major challenges in safety evaluation and effectiveness validation. We developed the Clinical Safety-Effectiveness Dual-Track Benchmark (CSEDB), a…
Traditional benchmarks for large language models (LLMs) typically rely on static evaluations through storytelling or opinion expression, which fail to capture the dynamic requirements of real-time information processing in contemporary…
LLMs have demonstrated impressive performance in answering medical questions, such as achieving passing scores on medical licensing examinations. However, medical board exams or general clinical questions do not capture the complexity of…
Can the rapid advances in code generation, function calling, and data analysis using large language models (LLMs) help automate the search and verification of hypotheses purely from a set of provided datasets? To evaluate this question, we…
Medical Large language models achieve strong scores on standard benchmarks; however, the transfer of those results to safe and reliable performance in clinical workflows remains a challenge. This survey reframes evaluation through a…
Medical document analysis plays a crucial role in extracting essential clinical insights from unstructured healthcare records, supporting critical tasks such as differential diagnosis. Determining the most probable condition among…
An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…